Etoposide
CHEBI:CHEBI_4911
Chemical Information
- Molecular Formula
- C29H32O13
- Molecular Mass
- 588.55660
- Charge
- 0
- SMILES
- [H][C@]12COC(=O)[C@]1([H])[C@H](c1cc(OC)c(O)c(OC)c1)c1cc3OCOc3cc1[C@H]2O[C@@H]1O[C@@H]2CO[C@@H](C)O[C@H]2[C@H](O)[C@H]1O
- InChI
- InChI=1S/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1
- InChIKey
- VJJPUSNTGOMMGY-MRVIYFEKSA-N
Alternative Names
- (-)-etoposide
- (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside
- 4-demethylepipodophyllotoxin beta-D-ethylideneglucoside
- 4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside)
- 9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-one
- Eposin
- Etopophos
- etoposide
- Etoposide
- Etoposido
- etoposidum
- Lastet
- Toposar
- trans-Etoposide
- Vepesid
- VP-16
Treatment Applications
-
obsolete esophageal metastasisView Disease →
DOID:1105
-
esophagus lymphomaView Disease →
DOID:1106
-
benign peritoneal mesotheliomaView Disease →
DOID:1789
-
esophagus leiomyosarcomaView Disease →
DOID:5276
-
esophagus liposarcomaView Disease →
DOID:5694
Drug Classification
-
beta-D-glucosideView Class →
CHEBI:22798
-
furonaphthodioxoleView Class →
CHEBI:50307
-
t230640
-
t230933
-
t231014
-
t231782
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 4179
- oboInOwl#hasDbXref
- Wikipedia:Etoposide
- core#notation
- CHEBI:4911
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_50305
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 4179
- oboInOwl#hasDbXref
- Wikipedia:Etoposide
- oboInOwl#id
- CHEBI:4911
- generic_name
- ETOPOSIDE
- brand_name
- ETOPOPHOS
- brand_name_base
- ETOPOPHOS
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- listing_expiration_date
- 20241231
- dosage_form
- INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
- labeler_name
- Catalent Germany Eberbach GmBH
- marketing_start_date
- 20010718
- product_ndc
- 63323-104
- application_number
- ANDA074983
- spl_id
- d672a555-bb0e-4a82-ac5e-5c9393b59c28
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_59517
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- core#notation
- CHEBI:4911
- rxcui
- 1734340
- route
- INTRAVENOUS
- active_ingredient_strength
- 4 kg/4kg
- package_marketing_start_date
- 20010718
- manufacturer_name
- Mylan Pharmaceuticals Inc.
- pharm_class_epc
- Topoisomerase Inhibitor [EPC]
- pharm_class
- Topoisomerase Inhibitors [MoA]
- pharm_class_moa
- Topoisomerase Inhibitors [MoA]
- active_ingredient_name
- ETOPOSIDE PHOSPHATE
- package_ndc
- 63323-104-50
- package_description
- 1 VIAL, MULTI-DOSE in 1 CARTON (63323-104-50) / 50 mL in 1 VIAL, MULTI-DOSE
- unii
- 528XYJ8L1N
- spl_set_id
- fe870629-104d-4d67-a7c6-f53bc588121e
- nui
- N0000000176
- upc
- 0363323104504
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_4786
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_113878
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect26396
- owl#annotatedSource
- t231853
- owl#someValuesFrom
- t711669