fluticasone
CHEBI:CHEBI_5134
Definition
A trifluorinated corticosteroid used in the form of its propionate ester for treatment of allergic rhinitis.
Chemical Information
- Molecular Formula
- C22H27F3O4S
- Molecular Mass
- 444.50800
- Charge
- 0
- SMILES
- [H][C@@]12C[C@@H](C)[C@](O)(C(=O)SCF)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C
- InChI
- InChI=1S/C22H27F3O4S/c1-11-6-13-14-8-16(24)15-7-12(26)4-5-19(15,2)21(14,25)17(27)9-20(13,3)22(11,29)18(28)30-10-23/h4-5,7,11,13-14,16-17,27,29H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1
- InChIKey
- MGNNYOODZCAHBA-GQKYHHCASA-N
Alternative Names
- fluticasona
- fluticasone
- fluticasonum
- S-(fluoromethyl) (6alpha,11beta,16alpha,17alpha)-6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carbothioate
Treatment Applications
-
acid anhydride respiratory allergyView Disease →
DOID:0040081
-
common coldView Disease →
DOID:10459
-
atrophic rhinitisView Disease →
DOID:4731
-
chronic rhinitisView Disease →
DOID:8252
Drug Classification
-
17alpha-hydroxy steroidView Class →
CHEBI:35342
-
3-oxo-Delta(4) steroidView Class →
CHEBI:47909
-
11beta-hydroxy steroidView Class →
CHEBI:35346
-
thioesterView Class →
CHEBI:51277
-
fluorinated steroidView Class →
CHEBI:50830
-
corticosteroidView Class →
CHEBI:50858
-
t241386
-
t241587
-
t241672
-
t241749
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 41126
- oboInOwl#hasDbXref
- Wikipedia:Fluticasone
- core#notation
- CHEBI:5134
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- brand_name_base
- Equate Allergy Relief
- product_ndc
- 76162-656
- brand_name
- RUGBY FLUTICASONE PROPIONATE NASAL
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 41126
- oboInOwl#hasDbXref
- Wikipedia:Fluticasone
- oboInOwl#id
- CHEBI:5134
- generic_name
- fluticasone furoate and vilanterol
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_50857
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#has_parent_hydride
- http://purl.obolibrary.org/obo/CHEBI_35509
- BFO_0000053
- http://purl.obolibrary.org/obo/DRON_00000060
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- labeler_name
- Quality Home Products
- dosage_form
- INJECTION, POWDER, FOR SUSPENSION
- application_number
- ANDA091553
- marketing_start_date
- 19990617
- spl_id
- 060fe06e-9de8-b5f2-e063-6394a90a6fd1
- package_marketing_start_date
- 20171120
- route
- NASAL
- package_ndc
- 62991-2698-4
- manufacturer_name
- Quality Home Products
- rxcui
- 2045382
- has_treatment
- http://purl.obolibrary.org/obo/DOID_11558
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_113110
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect27898
- owl#annotatedSource
- t242269
- owl#someValuesFrom
- t3201488
- listing_expiration_date
- 20241231
- package_description
- 1 POUCH in 1 CARTON (59310-520-08) / 1 INHALER in 1 POUCH / 60 POWDER, METERED in 1 INHALER
- active_ingredient_name
- UMECLIDINIUM BROMIDE
- active_ingredient_strength
- 93 ug/1
- spl_set_id
- 45ffaf45-8b88-44ba-804b-c2b563589898
- core#notation
- CHEBI:5134
- brand_name_suffix
- Nasal Alergy
- pharm_class
- Cholinergic Antagonists [MoA]
- upc
- 0645981000320
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- unii
- 7AN603V4JV