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levoleucovorin

CHEBI:CHEBI_63606

Definition

The pharmacologically active (6S)-stereoisomer of 5-formyltetrahydrofolic acid.

Chemical Information

Molecular Formula
C20H23N7O7
Molecular Mass
473.43930
Charge
0
SMILES
[H]C(=O)N1[C@@H](CNc2ccc(cc2)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CNc2nc(N)[nH]c(=O)c12
InChI
InChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/t12-,13-/m0/s1
InChIKey
VVIAGPKUTFNRDU-STQMWFEESA-N

Alternative Names

  • (6S)-5-Formyl-5,6,7,8-tetrahydrofolic acid
  • (6S)-Folinic acid
  • (6S)-Leucovorin
  • (S)-Leucovorin
  • Citrovorum factor
  • L-Folinic acid
  • Levofolene
  • Levofolinic acid
  • levoleucovorin
  • N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
  • N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
877015
oboInOwl#hasDbXref
Reaxys:101690
core#notation
CHEBI:63606

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
877015
oboInOwl#hasDbXref
Reaxys:101690
oboInOwl#id
CHEBI:63606
core#notation
CHEBI:63606
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35610
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_57457
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_57457
owl#someValuesFrom
t2991188
owl#annotatedSource
t262984