Discuss This Drug

Sotalol

CHEBI:CHEBI_63622

Definition

A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.

Chemical Information

Molecular Formula
C12H20N2O3S
Molecular Mass
272.36400
Charge
0
SMILES
CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1
InChI
InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3
InChIKey
ZBMZVLHSJCTVON-UHFFFAOYSA-N

Alternative Names

  • 4'-(1-hydroxy-2-(isopropylamino)ethyl)methane sulfonanilide
  • beta-cardone
  • N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide
  • sotalol
  • Sotalol
  • sotalolum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:63622
DRON_00010000
9947
oboInOwl#hasDbXref
Wikipedia:Sotalol

Additional References

Wikipedia:Sotalol

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

rxcui
1593731
manufacturer_name
Upsher-Smith Laboratories, Inc.
package_marketing_start_date
20190415
unii
HEC37C70XX
spl_set_id
0fd4afc7-dbf8-46be-9657-aa83bbb2c026
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
SOLUTION
labeler_name
Skyepharma Production SAS
marketing_start_date
19961205
application_number
ANDA077616
product_ndc
60505-0159
package_description
1 kg in 1 DRUM (12828-0071-2)
package_ndc
76385-114-50
listing_expiration_date
20241231
route
INTRAVENOUS
spl_id
f4a2f8f9-7dc8-395b-e053-2995a90a6f00
core#notation
CHEBI:63622
brand_name_suffix
AF
pharm_class
Cardiac Rhythm Alteration [PE]
active_ingredient_strength
80 mg/80mg
active_ingredient_name
SOTALOL HYDROCHLORIDE
upc
0372789135014
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
9947
oboInOwl#hasDbXref
Wikipedia:Sotalol
oboInOwl#id
CHEBI:63622
oboInOwl#hasAlternativeId
CHEBI:9206
brand_name
Betapace AF
brand_name_base
Betapace AF
generic_name
sotalol HCl
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35530
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00020323
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_63647
has_treatment
http://purl.obolibrary.org/obo/DOID_0070535
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_108700
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect30638
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_63647
owl#annotatedSource
t262950
owl#someValuesFrom
t2996069