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Levamisole

CHEBI:CHEBI_6432

Definition

A 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole that has S configuration. It is used (generally as the monohydrochloride salt) to treat parasitic worm infections in pigs, sheep and cattle and was formerly used in humans as an adjuvant to chemotherapy for the treatment of various cancers. It is also widely used as an adulterant to coccaine.

Chemical Information

Molecular Formula
C11H12N2S
Molecular Mass
204.29100
Charge
0
SMILES
C1CN2C[C@@H](N=C2S1)c1ccccc1
InChI
InChI=1S/C11H12N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-5,10H,6-8H2/t10-/m1/s1
InChIKey
HLFSDGLLUJUHTE-SNVBAGLBSA-N

Alternative Names

  • (-)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole
  • (-)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole
  • (-)-tetramisole
  • (6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole
  • (S)-(-)-levamisole
  • (S)-(-)-tetramisole
  • (S)-2,3,5,6-tetrahydro-6-phenylimidazo[2,1-b]thiazole
  • Ketrax
  • Lepuron
  • levamisol
  • levamisole
  • levamisolum
  • Levomysol
  • Levovermax
  • Totalon
  • Wormicid

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:6432
DRON_00010000
6371
oboInOwl#hasDbXref
Wikipedia:Levamisole

Additional References

Wikipedia:Levamisole

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:6432
active_ingredient_strength
1 kg/kg
active_ingredient_name
LEVAMISOLE HYDROCHLORIDE
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
6371
oboInOwl#hasDbXref
Wikipedia:Levamisole
oboInOwl#id
CHEBI:6432
listing_expiration_date
20251231
dosage_form
POWDER
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
labeler_name
Nanjing White Whale Pharmaceutical Co., Ltd
marketing_start_date
20100309
generic_name
LEVAMISOLE PHOSPHATE
product_ndc
66478-0165
spl_id
b1bfe71e-1f3d-43af-e053-2995a90ab4d0
package_ndc
66478-0165-1
package_description
1 BAG in 1 DRUM (66478-0165-1) / 25 kg in 1 BAG
package_marketing_start_date
09-MAR-10
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35444
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_enantiomer_of
http://purl.obolibrary.org/obo/CHEBI_77282
has_treatment
http://purl.obolibrary.org/obo/DOID_14422
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_111420
owl#annotatedSource
t266412
owl#someValuesFrom
t894343