first generation antipsychotic
CHEBI:CHEBI_65190
Definition
Antipsychotic drugs which can have different modes of action but which tend to be more likely than second generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements; such body movements can become permanent even after treatment has ceased.
Alternative Names
- first generation antipsychotic agent
- first generation antipsychotic agents
- first generation antipsychotic drug
- first generation antipsychotic drugs
- first generation antipsychotics
- typical antipsychotic
- typical antipsychotic agent
- typical antipsychotic agents
- typical antipsychotic drug
- typical antipsychotic drugs
- typical antipsychotics
Treatment Applications
-
Partington syndromeView Disease →
DOID:14744
-
spastic ectropionView Disease →
DOID:1571
-
myasthenia gravisView Disease →
DOID:437
-
Angelman syndromeView Disease →
DOID:1932
-
lateral sclerosisView Disease →
DOID:230
-
stereotypic movement disorderView Disease →
DOID:2303
-
transient tic disorderView Disease →
DOID:2768
-
Coffin-Lowry syndromeView Disease →
DOID:3783
-
obsolete psychomotor diseaseView Disease →
DOID:4020
-
akinetic mutismView Disease →
DOID:4267
-
dysgraphiaView Disease →
DOID:4540
-
ideomotor apraxiaView Disease →
DOID:4627
-
Gerstmann syndromeView Disease →
DOID:4969
-
Becker muscular dystrophyView Disease →
DOID:9883
-
congenital muscular dystrophyView Disease →
DOID:0050557
-
biotin-responsive basal ganglia diseaseView Disease →
DOID:0050659
-
ataxic cerebral palsyView Disease →
DOID:0050670
-
dyskinetic cerebral palsyView Disease →
DOID:0050672
-
Birk-Barel syndromeView Disease →
DOID:0050675
-
anismusView Disease →
DOID:0050839
-
focal hand dystoniaView Disease →
DOID:0050841
-
oromandibular dystoniaView Disease →
DOID:0050843
-
hemidystoniaView Disease →
DOID:0050846
-
hereditary ataxiaView Disease →
DOID:0050951
-
spinocerebellar ataxia type 27View Disease →
DOID:0050976
-
autism spectrum disorderView Disease →
DOID:0060041
-
aphasiaView Disease →
DOID:0060046
-
agraphiaView Disease →
DOID:0060223
-
basal ganglia calcificationView Disease →
DOID:0060230
-
Smith-McCort dysplasiaView Disease →
DOID:0060247
-
chromosome 15q11.2 deletion syndromeView Disease →
DOID:0060393
-
torsion dystonia 1View Disease →
DOID:0060730
-
rippling muscle disease 1View Disease →
DOID:0070308
-
cylindrical spirals myopathyView Disease →
DOID:0080103
-
hypermanganesemia with dystoniaView Disease →
DOID:0080535
-
Kleefstra syndromeView Disease →
DOID:0080597
-
obsolete MECP2 duplication syndromeView Disease →
DOID:0080713
-
bilateral generalized polymicrogyriaView Disease →
DOID:0080920
-
bilateral frontal polymicrogyriaView Disease →
DOID:0080921
-
spastic paraplegia with deafnessView Disease →
DOID:0081100
-
X-linked mental retardation Gustavson typeView Disease →
DOID:0081123
-
oculopharyngodistal myopathyView Disease →
DOID:0081296
-
oculopharyngodistal myopathy 2View Disease →
DOID:0081298
-
oculopharyngodistal myopathy 4View Disease →
DOID:0081300
-
myofibrillar myopathy 11View Disease →
DOID:0081338
-
congenital myopathy 2BView Disease →
DOID:0081339
-
congenital myopathy 8View Disease →
DOID:0081342
-
congenital myopathy 20View Disease →
DOID:0081352
-
spinal muscular atrophy, Jokela typeView Disease →
DOID:0081356
-
distal myopathy with rimmed vacuolesView Disease →
DOID:0081363
-
logopenic progressive aphasiaView Disease →
DOID:0081389
-
semantic dementiaView Disease →
DOID:0081391
-
myoclonic dystoniaView Disease →
DOID:0090033
-
myoclonic dystonia 11View Disease →
DOID:0090034
-
myoclonic dystonia 15View Disease →
DOID:0090035
-
myoclonic dystonia 26View Disease →
DOID:0090036
-
torsion dystonia 13View Disease →
DOID:0090037
-
torsion dystonia 2View Disease →
DOID:0090038
-
torsion dystonia 6View Disease →
DOID:0090039
-
torsion dystonia 7View Disease →
DOID:0090040
-
torsion dystonia 4View Disease →
DOID:0090041
-
torsion dystonia 17View Disease →
DOID:0090042
-
dystonia 21View Disease →
DOID:0090046
-
dystonia 27View Disease →
DOID:0090050
-
dystonia 23View Disease →
DOID:0090051
-
dystonia 24View Disease →
DOID:0090052
-
episodic kinesigenic dyskinesia 1View Disease →
DOID:0090053
-
episodic kinesigenic dyskinesia 2View Disease →
DOID:0090054
-
dystonia 25View Disease →
DOID:0090055
-
torsion dystonia with onset in infancyView Disease →
DOID:0090058
-
movement diseaseView Disease →
DOID:480
-
dystoniaView Disease →
DOID:543
-
basal ganglia diseaseView Disease →
DOID:679
-
episodic ataxiaView Disease →
DOID:963
-
hereditary spastic paraplegia 18View Disease →
DOID:0110771
-
hereditary spastic paraplegia 2View Disease →
DOID:0110773
-
hereditary spastic paraplegia 7View Disease →
DOID:0110816
-
congenital mirror movement disorderView Disease →
DOID:0111153
-
essential tremor 1View Disease →
DOID:0111428
-
progressive myoclonus epilepsy 4View Disease →
DOID:0111444
-
progressive myoclonus epilepsy 7View Disease →
DOID:0111447
-
progressive myoclonus epilepsy 6View Disease →
DOID:0111449
-
familial adult myoclonic epilepsy 2View Disease →
DOID:0111692
-
hereditary spastic paraplegia 85View Disease →
DOID:0112345
-
Unverricht-Lundborg syndromeView Disease →
DOID:3535
-
juvenile myoclonic epilepsyView Disease →
DOID:4890
-
essential tremorView Disease →
DOID:4990
-
chronic tic disorderView Disease →
DOID:10600
-
spastic hemiplegiaView Disease →
DOID:10967
-
Gilles de la Tourette syndromeView Disease →
DOID:11119
-
Duchenne muscular dystrophyView Disease →
DOID:11723
-
pseudobulbar palsyView Disease →
DOID:12680
-
myoclonic cerebellar dyssynergiaView Disease →
DOID:12707
-
autistic disorderView Disease →
DOID:12849
-
choreatic diseaseView Disease →
DOID:12859
-
Stiff-Person syndromeView Disease →
DOID:13366
-
neuroleptic malignant syndromeView Disease →
DOID:14464
-
tic disorderView Disease →
DOID:2769
Drug Classification
-
antipsychotic agentView Class →
CHEBI:35476
-
phenothiazine antipsychotic drugView Class →
CHEBI:37930
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- core#notation
- CHEBI:65190
- oboInOwl#hasDbXref
- Wikipedia:Typical_antipsychotic
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#id
- CHEBI:65190
- core#notation
- CHEBI:65190
- oboInOwl#hasDbXref
- Wikipedia:Typical_antipsychotic
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_108985
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_9711
- owl#someValuesFrom
- t323909
- owl#annotatedSource
- t269805