Discuss This Drug

Desoximetasone

CHEBI:CHEBI_691037

Definition

Dexamethasone in which the hydroxy group at the 17alpha position is substituted by hydrogen. A synthetic corticosteroid with glucocorticoid activity, it is used as an anti-inflammatory and anti-pruritic in the treatment of various skin disorders, including skin allergies and psoriasis.

Chemical Information

Molecular Formula
C22H29FO4
Molecular Mass
376.46170
Charge
0
SMILES
[H][C@@]12C[C@@H](C)[C@H](C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
InChI
InChI=1S/C22H29FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,12,15-16,18-19,24,27H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,18+,19-,20+,21+,22+/m1/s1
InChIKey
VWVSBHGCDBMOOT-IIEHVVJPSA-N

Alternative Names

  • (11beta,16alpha)-9-fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
  • 9-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
  • 9alpha-fluoro-16alpha-methyl-Delta(1)-corticosterone
  • desoximetasona
  • desoximetasone
  • desoximetasonum
  • desoxymethasone

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
3255
oboInOwl#hasDbXref
Wikipedia:Desoximetasone
core#notation
CHEBI:691037

Additional References

Wikipedia:Desoximetasone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113905
owl#annotatedSource
t276646
owl#someValuesFrom
t2914959
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
3255
oboInOwl#hasDbXref
Wikipedia:Desoximetasone
oboInOwl#id
CHEBI:691037
generic_name
DESOXIMETASONE MICRONIZED
brand_name
Topicort
brand_name_base
Topicort
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
SPRAY
product_ndc
51672-5205
application_number
ANDA073210
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_59683
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
route
TOPICAL
package_ndc
51672-5205-7
package_description
1 TUBE in 1 CARTON (51672-5205-7) / 100 g in 1 TUBE
spl_id
15a31bdf-5162-42bd-a3d5-7e21bac5f49f
package_marketing_start_date
19921215
core#notation
CHEBI:691037
pharm_class_moa
Corticosteroid Hormone Receptor Agonists [MoA]
pharm_class
Corticosteroid [EPC]
pharm_class_epc
Corticosteroid [EPC]
upc
0368180944331
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
listing_expiration_date
20241231
labeler_name
Glenmark Pharmaceuticals Inc., USA
marketing_start_date
19921215
rxcui
1376340
manufacturer_name
Glenmark Pharmaceuticals Inc., USA
active_ingredient_name
DESOXIMETASONE
active_ingredient_strength
2.5 mg/mL
unii
4E07GXB7AU
spl_set_id
37eb1205-1743-4480-8631-b0bbcaeb8359
nui
N0000175450