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ceftaroline

CHEBI:CHEBI_70729

Definition

A cephalosporin that is the active metabolite of the prodrug ceftaroline fosamil. Used for the treatment of adults with acute bacterial skin and skin structure infections.

Chemical Information

Molecular Formula
C22H20N8O5S4
Molecular Mass
604.70500
Charge
0
SMILES
[H][C@]12SCC(Sc3nc(cs3)-c3cc[n+](C)cc3)=C(N1C(=O)[C@H]2NC(=O)C(=N/OCC)\c1nsc(N)n1)C([O-])=O
InChI
InChI=1S/C22H20N8O5S4/c1-3-35-27-13(16-26-21(23)39-28-16)17(31)25-14-18(32)30-15(20(33)34)12(9-36-19(14)30)38-22-24-11(8-37-22)10-4-6-29(2)7-5-10/h4-8,14,19H,3,9H2,1-2H3,(H3-,23,25,26,28,31,33,34)/b27-13-/t14-,19-/m1/s1
InChIKey
RGFBRLNVZCCMSV-BIRGHMBHSA-N

Alternative Names

  • (6R,7R)-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(ethoxyimino)acetyl]amino}-3-{[4-(1-methylpyridinium-4-yl)-1,3-thiazol-2-yl]sulfanyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • PPI 0903M
  • T 91825
  • T-91825

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1040005
oboInOwl#hasDbXref
Reaxys:9532372
core#notation
CHEBI:70729

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1040005
oboInOwl#hasDbXref
Reaxys:9532372
generic_name
ceftaroline fosamil
oboInOwl#id
CHEBI:70729
core#notation
CHEBI:70729
rxcui
1040016
product_type
HUMAN PRESCRIPTION DRUG
marketing_category
NDA
labeler_name
Allergan, Inc.
manufacturer_name
Allergan, Inc.
listing_expiration_date
20251231
pharm_class
Cephalosporins [CS]
route
INTRAVENOUS
dosage_form
POWDER, FOR SOLUTION
marketing_start_date
20101029
package_marketing_start_date
20101029
brand_name
Teflaro
brand_name_base
Teflaro
product_ndc
0456-0600
application_number
NDA200327
spl_id
0804a64c-0359-4cc1-9e02-23d7efb7afbf
active_ingredient_name
CEFTAROLINE FOSAMIL
active_ingredient_strength
600 mg/20mL
package_ndc
0456-0600-10
package_description
10 VIAL, SINGLE-DOSE in 1 CARTON (0456-0600-10) / 20 mL in 1 VIAL, SINGLE-DOSE (0456-0600-01)
unii
7P6FQA5D21
spl_set_id
3ecde48b-75a2-4beb-9999-369f3f61bb8a
upc
0304560400103
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_49103
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_107099
has_treatment
http://purl.obolibrary.org/obo/DOID_12375
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_70718
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect33151
owl#annotatedSource
t276761
owl#someValuesFrom
t666632