Discuss This Drug

Masoprocol

CHEBI:CHEBI_73468

Definition

The meso-form of nordihydroguaiaretic acid. An antioxidant found in the creosote bush, Larrea divaricata, it is a potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. It also inhibits (though to a lesser extent) formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase.

Chemical Information

Molecular Formula
C18H22O4
Molecular Mass
302.36490
Charge
0
SMILES
C[C@@H](Cc1ccc(O)c(O)c1)[C@H](C)Cc1ccc(O)c(O)c1
InChI
InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3/t11-,12+
InChIKey
HCZKYJDFEPMADG-TXEJJXNPSA-N

Alternative Names

  • 4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol
  • Actinex
  • CHX 100
  • CHX-100
  • erythro-nordihydroguaiaretic acid
  • masoprocol
  • masoprocolum
  • meso-1,4-bis(3,4-dihydroxyphenyl)-2,3-dimethylbutane
  • meso-2,3-bis(3,4-dihydroxyphenylmethyl)butane
  • meso-4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol
  • meso-4,4'-(2,3-dimethyl-1,4-butanediyl)bis(pyrocatechol)
  • meso-4,4'-(2,3-dimethyltetramethylene)dipyrocatechol
  • meso-beta,gamma-dimethyl-alpha,delta-bis(3,4-dihydroxyphenyl)butan
  • meso-NDGA
  • meso-nordihydroguaiaretic acid

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
227239
oboInOwl#hasDbXref
Wikipedia:Masoprocol
core#notation
CHEBI:73468

Additional References

Wikipedia:Masoprocol

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
227239
oboInOwl#hasDbXref
Wikipedia:Masoprocol
oboInOwl#id
CHEBI:73468
core#notation
CHEBI:73468
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35856
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
owl#annotatedSource
t283715
owl#someValuesFrom
t1447311