nordihydroguaiaretic acid
CHEBI:CHEBI_7625
Definition
A tetrol that is butane which is substituted at positions 2 and 3 by 3,4-dihydroxybenzyl groups. Masoprocol, the meso-form found in the leaves of the creosote bush (Larrea divaricata), is a potent lipoxygenase inhibitor.
Chemical Information
- Molecular Formula
- C18H22O4
- Molecular Mass
- 302.36490
- Charge
- 0
- SMILES
- CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1
- InChI
- InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3
- InChIKey
- HCZKYJDFEPMADG-UHFFFAOYSA-N
Alternative Names
- 1,4-bis(3,4-dihydroxyphenyl)-2,3-dimethylbutane
- 2,3-bis(3,4-dihydroxyphenylmethyl)butane
- 4,4'-(2,3-dimethyl-1,4-butanediyl)bis(pyrocatechol)
- 4,4'-(2,3-dimethylbutane-1,4-diyl)dibenzene-1,2-diol
- 4,4'-(2,3-dimethyltetramethylene)dipyrocatechol
- beta,gamma-dimethyl-alpha,delta-bis(3,4-dihydroxyphenyl)butane
- NDGA
- nordihydroguaiaretic acid
- nordihydroguaiaretic acid (unspecified)
- norhydroguaiaretic acid
- NSC 4291
Drug Classification
-
catecholsView Class →
CHEBI:33566
-
tetrolView Class →
CHEBI:33573
-
lignanView Class →
CHEBI:25036
-
t289246
-
t289334
-
t289998
-
t290461
-
masoprocolView Class →
CHEBI:73468
-
MasoprocolView Class →
CHEBI:73468
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Nordihydroguaiaretic_acid
- core#notation
- CHEBI:7625
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Nordihydroguaiaretic_acid
- oboInOwl#id
- CHEBI:7625
- core#notation
- CHEBI:7625
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_76924
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- owl#annotatedSource
- t290353