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nordihydroguaiaretic acid

CHEBI:CHEBI_7625

Definition

A tetrol that is butane which is substituted at positions 2 and 3 by 3,4-dihydroxybenzyl groups. Masoprocol, the meso-form found in the leaves of the creosote bush (Larrea divaricata), is a potent lipoxygenase inhibitor.

Chemical Information

Molecular Formula
C18H22O4
Molecular Mass
302.36490
Charge
0
SMILES
CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1
InChI
InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3
InChIKey
HCZKYJDFEPMADG-UHFFFAOYSA-N

Alternative Names

  • 1,4-bis(3,4-dihydroxyphenyl)-2,3-dimethylbutane
  • 2,3-bis(3,4-dihydroxyphenylmethyl)butane
  • 4,4'-(2,3-dimethyl-1,4-butanediyl)bis(pyrocatechol)
  • 4,4'-(2,3-dimethylbutane-1,4-diyl)dibenzene-1,2-diol
  • 4,4'-(2,3-dimethyltetramethylene)dipyrocatechol
  • beta,gamma-dimethyl-alpha,delta-bis(3,4-dihydroxyphenyl)butane
  • NDGA
  • nordihydroguaiaretic acid
  • nordihydroguaiaretic acid (unspecified)
  • norhydroguaiaretic acid
  • NSC 4291

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Nordihydroguaiaretic_acid
core#notation
CHEBI:7625

Additional References

Wikipedia:Nordihydroguaiaretic_acid

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Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Nordihydroguaiaretic_acid
oboInOwl#id
CHEBI:7625
core#notation
CHEBI:7625
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_76924
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
owl#annotatedSource
t290353