dapagliflozin
CHEBI:CHEBI_85078
Definition
A C-glycosyl comprising beta-D-glucose in which the anomeric hydroxy group is replaced by a 4-chloro-3-(4-ethoxybenzyl)phenyl group. Used (in the form of its propanediol monohydrate) to improve glycemic control, along with diet and exercise, in adults with type 2 diabetes.
Chemical Information
- Molecular Formula
- C21H25ClO6
- Molecular Mass
- 408.87300
- Charge
- 0
- SMILES
- CCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1
- InChI
- InChI=1S/C21H25ClO6/c1-2-27-15-6-3-12(4-7-15)9-14-10-13(5-8-16(14)22)21-20(26)19(25)18(24)17(11-23)28-21/h3-8,10,17-21,23-26H,2,9,11H2,1H3/t17-,18-,19+,20-,21+/m1/s1
- InChIKey
- JVHXJTBJCFBINQ-ADAARDCZSA-N
Alternative Names
- (1S)-1,5-anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D-glucitol
- (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6- (hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
- BMS 512148
- BMS-512148
- dapagliflozin
Treatment Applications
Drug Classification
-
aromatic etherView Class →
CHEBI:35618
-
monochlorobenzenesView Class →
CHEBI:83403
-
C-glycosyl compoundView Class →
CHEBI:20857
-
t309967
-
t310679
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 1488564
- oboInOwl#hasDbXref
- Wikipedia:Dapagliflozin
- core#notation
- CHEBI:85078
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 1488564
- oboInOwl#hasDbXref
- Wikipedia:Dapagliflozin
- oboInOwl#id
- CHEBI:85078
- core#notation
- CHEBI:85078
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_73273
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_783
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_108851
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect36812
- owl#annotatedSource
- t311000
- owl#someValuesFrom
- t3580013