ICD-10: B76

Hookworm diseases

Clinical Information

Includes

  • uncinariasis

Additional Information

Clinical Information

Hookworm diseases, classified under ICD-10 code B76, primarily refer to infections caused by hookworms, which are parasitic nematodes. The two most common species affecting humans are Ancylostoma duodenale and Necator americanus. Understanding the clinical presentation, signs, symptoms, and patient characteristics associated with hookworm diseases is crucial for effective diagnosis and treatment.

Clinical Presentation

Signs and Symptoms

The clinical manifestations of hookworm infections can vary based on the severity of the infection and the host's immune response. Common signs and symptoms include:

  • Anemia: Due to blood loss from the intestinal mucosa, patients often present with iron-deficiency anemia, which can lead to fatigue, weakness, and pallor[1].
  • Abdominal Pain: Patients may experience cramping or discomfort in the abdominal region, often due to the worms' attachment to the intestinal wall[2].
  • Diarrhea: Frequent loose stools can occur, sometimes accompanied by mucus or blood, particularly in severe cases[3].
  • Dermatitis: Cutaneous larva migrans may occur, characterized by itchy, serpiginous lesions on the skin, typically at the site of larval penetration[4].
  • Nausea and Vomiting: Some patients may report gastrointestinal upset, including nausea and vomiting, particularly in acute cases[5].

Asymptomatic Cases

It is important to note that many individuals with hookworm infections may remain asymptomatic, especially in cases of mild infection. This can lead to underdiagnosis and untreated infections, which can have long-term health implications[6].

Patient Characteristics

Demographics

  • Geographic Distribution: Hookworm infections are prevalent in tropical and subtropical regions, particularly in areas with poor sanitation and hygiene practices. They are common in parts of Africa, Asia, and Latin America[7].
  • Age: While hookworm infections can affect individuals of any age, children and young adults are particularly vulnerable due to their higher exposure to contaminated soil and inadequate sanitation[8].
  • Socioeconomic Status: Individuals from lower socioeconomic backgrounds are at greater risk due to limited access to clean water, sanitation facilities, and healthcare services[9].

Risk Factors

  • Occupational Exposure: People who work in agriculture or outdoor occupations, especially in endemic areas, are at higher risk of infection due to soil exposure[10].
  • Nutritional Status: Malnutrition can exacerbate the effects of hookworm infections, leading to more severe symptoms and complications[11].
  • Immunocompromised Individuals: Those with weakened immune systems, such as individuals with HIV/AIDS or other chronic illnesses, may experience more severe manifestations of the disease[12].

Conclusion

Hookworm diseases, represented by ICD-10 code B76, present a range of clinical symptoms primarily related to gastrointestinal distress and anemia. The demographic characteristics of affected individuals often reflect broader socioeconomic and environmental factors. Awareness of these clinical presentations and patient characteristics is essential for healthcare providers to facilitate timely diagnosis and treatment, ultimately reducing the burden of this preventable disease.

For further management, it is crucial to consider both medical treatment and public health interventions aimed at improving sanitation and hygiene practices in endemic areas.

Approximate Synonyms

Hookworm diseases, classified under the ICD-10 code B76, encompass a range of conditions caused by parasitic infections from hookworms. Understanding the alternative names and related terms for this classification can enhance clarity in medical documentation and communication. Below are some of the key alternative names and related terms associated with ICD-10 code B76.

Alternative Names for Hookworm Diseases

  1. Ancylostomiasis: This term specifically refers to infections caused by the Ancylostoma species of hookworms, which are prevalent in many tropical and subtropical regions.

  2. Necatoriasis: This name is used for infections caused by Necator americanus, another common species of hookworm that affects humans.

  3. Hookworm Infection: A general term that describes the presence of hookworms in the intestines, leading to various symptoms and health issues.

  4. Intestinal Hookworm Disease: This term emphasizes the gastrointestinal aspect of the infection, highlighting its primary site of impact.

  5. Hookworm Disease: A broader term that encompasses all types of diseases caused by hookworms, including those caused by different species.

  1. Helminthiasis: A general term for infections caused by helminths (parasitic worms), which includes hookworms among other types of worms.

  2. Parasitic Infection: This term refers to infections caused by parasites, including hookworms, which can lead to various health complications.

  3. Soil-Transmitted Helminth Infections (STH): Hookworm diseases fall under this category, as they are transmitted through contaminated soil, particularly in areas with poor sanitation.

  4. Anemia: A common complication of hookworm infections due to blood loss from the intestinal lining, often associated with these diseases.

  5. Malnutrition: Chronic hookworm infections can lead to malnutrition, particularly in children, due to nutrient absorption issues.

Conclusion

Understanding the alternative names and related terms for ICD-10 code B76: Hookworm diseases is crucial for healthcare professionals in accurately diagnosing and treating these infections. The terminology not only aids in clinical communication but also enhances the understanding of the disease's impact on public health. If you have further questions or need more specific information, feel free to ask!

Diagnostic Criteria

The ICD-10 code B76 refers to "Hookworm diseases," which are primarily caused by parasitic infections from hookworms, notably Ancylostoma duodenale and Necator americanus. Diagnosing hookworm diseases involves a combination of clinical evaluation, laboratory tests, and epidemiological factors. Below are the key criteria used for diagnosis:

Clinical Symptoms

  1. Anemia: One of the most common manifestations of hookworm infection is iron-deficiency anemia, resulting from blood loss due to the worms' feeding on the intestinal mucosa.
  2. Gastrointestinal Symptoms: Patients may present with abdominal pain, diarrhea, and nausea. These symptoms can vary in severity depending on the intensity of the infection.
  3. Fatigue and Weakness: Due to anemia and nutrient deficiencies, individuals may experience general fatigue and weakness.
  4. Dermatological Signs: In cases of cutaneous larva migrans, a condition caused by Ancylostoma braziliense, patients may exhibit skin rashes or lesions at the site of larval penetration.

Laboratory Tests

  1. Stool Examination: The definitive diagnosis of hookworm infection is made through the identification of hookworm eggs in stool samples. This is typically performed using a microscopic examination of a stool sample.
  2. Complete Blood Count (CBC): A CBC may reveal anemia, characterized by low hemoglobin levels and low red blood cell counts, which can support the diagnosis.
  3. Serological Tests: Although not routinely used, serological tests can help in identifying specific antibodies against hookworm infections in certain cases.

Epidemiological Factors

  1. Geographical Distribution: Hookworm infections are more prevalent in tropical and subtropical regions, particularly in areas with poor sanitation and hygiene practices. A history of travel or residence in endemic areas can be a significant factor in diagnosis.
  2. Exposure History: Information regarding exposure to contaminated soil, particularly in individuals who walk barefoot or engage in agricultural activities, can aid in the diagnosis.

Differential Diagnosis

It is essential to differentiate hookworm diseases from other conditions that may present with similar symptoms, such as other types of helminth infections, gastrointestinal disorders, or nutritional deficiencies. A thorough clinical history and appropriate laboratory tests are crucial for accurate diagnosis.

Conclusion

In summary, the diagnosis of hookworm diseases (ICD-10 code B76) relies on a combination of clinical symptoms, laboratory findings, and epidemiological context. Accurate diagnosis is vital for effective treatment and management of the infection, which typically involves antiparasitic medications such as albendazole or mebendazole. Early diagnosis and treatment can significantly improve patient outcomes and reduce the risk of complications associated with hookworm infections.

Treatment Guidelines

Hookworm diseases, classified under ICD-10 code B76, are caused primarily by two species of hookworms: Ancylostoma duodenale and Necator americanus. These parasitic infections are prevalent in tropical and subtropical regions and can lead to significant health issues, including anemia and malnutrition. The standard treatment approaches for hookworm diseases focus on antiparasitic medications, supportive care, and preventive measures.

Antiparasitic Medications

The cornerstone of treatment for hookworm infections is the use of antiparasitic drugs. The following medications are commonly prescribed:

1. Albendazole

Albendazole is a broad-spectrum anthelmintic that is effective against a variety of helminths, including hookworms. The typical dosage for adults and children over two years old is a single oral dose of 400 mg. It works by inhibiting the metabolism of the parasites, leading to their death and subsequent elimination from the body[1].

2. Mebendazole

Mebendazole is another effective treatment option, often used in a similar manner to albendazole. The standard dosage is 100 mg taken twice daily for three days or a single dose of 500 mg. Mebendazole disrupts the energy production of the parasites, ultimately leading to their death[1][2].

3. Pyrantel Pamoate

Pyrantel pamoate is an alternative treatment that can be used, particularly in cases where other medications are contraindicated. It is typically administered as a single dose of 11 mg/kg (up to a maximum of 1 g) and works by paralyzing the worms, allowing them to be expelled from the gastrointestinal tract[2].

Supportive Care

In addition to antiparasitic treatment, supportive care is crucial, especially in cases where the patient presents with anemia or nutritional deficiencies due to hookworm infection. This may include:

  • Iron Supplementation: To address anemia, iron supplements may be prescribed to replenish iron stores and improve hemoglobin levels[3].
  • Nutritional Support: A balanced diet rich in iron and other essential nutrients is recommended to aid recovery and improve overall health[3].

Preventive Measures

Preventing hookworm infections is essential, particularly in endemic areas. Key preventive strategies include:

  • Improved Sanitation: Ensuring access to clean water and proper sanitation facilities can significantly reduce the transmission of hookworms[4].
  • Health Education: Educating communities about the importance of wearing shoes and practicing good hygiene can help prevent infections[4].
  • Regular Screening and Treatment: In high-risk populations, regular screening for hookworm infections and prompt treatment can help control outbreaks and reduce morbidity[4].

Conclusion

The management of hookworm diseases under ICD-10 code B76 involves a combination of effective antiparasitic medications, supportive care to address complications like anemia, and preventive measures to reduce transmission. By implementing these strategies, healthcare providers can significantly improve patient outcomes and reduce the burden of hookworm infections in affected populations. Regular follow-up and community education are also vital components of a comprehensive approach to managing this public health issue.

References

  1. ICD-10 International statistical classification of diseases.
  2. Descriptive Epidemiology of Soil-Transmitted Helminth.
  3. Standard Treatment Guidelines and Essential Medicines.
  4. Helminth infections in the US military: from strongyloidiasis to hookworm.

Description

Clinical Description of Hookworm Diseases (ICD-10 Code B76)

Hookworm diseases, classified under ICD-10 code B76, are caused by parasitic infections primarily from two species of hookworms: Ancylostoma duodenale and Necator americanus. These parasites are prevalent in tropical and subtropical regions, where they can lead to significant health issues, particularly in areas with poor sanitation and hygiene practices.

Pathophysiology

Hookworms attach to the intestinal wall of the host, where they feed on blood. This feeding can lead to iron deficiency anemia due to blood loss, as well as protein deficiency, which can result in a range of symptoms. The larvae typically enter the human body through the skin, often via bare feet, and migrate through the bloodstream to the lungs, where they are coughed up and swallowed, eventually reaching the intestines.

Symptoms

The clinical manifestations of hookworm disease can vary based on the severity of the infection and the host's nutritional status. Common symptoms include:

  • Anemia: Due to chronic blood loss, leading to fatigue, weakness, and pallor.
  • Abdominal pain: Often crampy and may be accompanied by diarrhea.
  • Nausea and vomiting: These gastrointestinal symptoms can occur, particularly in severe cases.
  • Weight loss: Resulting from malnutrition and poor absorption of nutrients.
  • Dermatitis: Skin irritation may occur at the site of larval entry, often referred to as "ground itch."

Diagnosis

Diagnosis of hookworm disease typically involves:

  • Stool examination: Microscopic identification of hookworm eggs in stool samples is the primary diagnostic method.
  • Blood tests: To assess for anemia and other nutritional deficiencies.

Treatment

The treatment for hookworm infections generally includes:

  • Anthelmintic medications: Such as albendazole or mebendazole, which are effective in eliminating the parasites.
  • Iron supplementation: To address anemia and improve hemoglobin levels.
  • Nutritional support: Ensuring adequate intake of nutrients to aid recovery.

Prevention

Preventive measures are crucial in controlling hookworm diseases, particularly in endemic areas. These include:

  • Improving sanitation: Access to clean water and proper sewage disposal can significantly reduce transmission.
  • Health education: Raising awareness about the importance of wearing shoes and practicing good hygiene.
  • Regular deworming programs: Especially in at-risk populations, such as children and pregnant women.

Conclusion

Hookworm diseases, represented by ICD-10 code B76, pose a significant public health challenge in many parts of the world. Understanding the clinical features, diagnostic methods, and treatment options is essential for effective management and prevention of this parasitic infection. Addressing the underlying social determinants of health, such as sanitation and education, is vital for reducing the incidence of hookworm diseases and improving overall health outcomes in affected populations.

Related Information

Clinical Information

Approximate Synonyms

  • Ancylostomiasis
  • Necatoriasis
  • Hookworm Infection
  • Intestinal Hookworm Disease
  • Hookworm Disease
  • Helminthiasis
  • Parasitic Infection
  • Soil-Transmitted Helminth Infections (STH)
  • Anemia
  • Malnutrition

Diagnostic Criteria

  • Anemia due to blood loss from worms
  • Abdominal pain, diarrhea, nausea
  • Fatigue and weakness due to anemia
  • Skin rashes or lesions in cutaneous larva migrans
  • Hookworm eggs in stool samples via microscopy
  • Low hemoglobin levels and red blood cell count
  • Serological tests for specific hookworm antibodies
  • Geographical distribution of hookworm infections
  • Exposure history to contaminated soil

Treatment Guidelines

  • Albendazole is a broad-spectrum anthelmintic.
  • Mebendazole disrupts energy production of parasites.
  • Pyrantel Pamoate paralyzes worms allowing expulsion.
  • Iron Supplementation addresses anemia and hemoglobin levels.
  • Nutritional Support aids recovery and improves health.
  • Improved Sanitation reduces transmission significantly.
  • Regular Screening and Treatment control outbreaks.

Description

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