obsolete Morganella morganii intestinal infectious disease

Morganella morganii intestinal infection, also known as Morganella morganii sepsis, is a bacterial infectious disease that affects the intestine.

• The disease is caused by the bacterium Morganella morganii, which is a facultative, anaerobic, gram-negative rod [6].
• It is an opportunistic pathogen that can cause infection in individuals with compromised immune systems or those who are already ill [5].
• Intestinal infection due to Morganella morganii is characterized by symptoms such as abdominal pain, diarrhea, and fever [3].
• In severe cases, the infection can lead to complications such as spontaneous intestinal perforation [9].

The disease was previously known as "Intestinal infection due to Morganella morganii (disorder)" but has been designated as an obsolete fully preferred term [3].

Morganella morganii is an opportunistic bacterium that can cause various infections, including urinary tract infections and gastrointestinal infections. However, its role in causing intestinal infectious diseases has been largely considered obsolete due to the advancements in medical treatments and practices.

Historically, Morganella morganii was associated with several signs and symptoms of intestinal infection, including:

• Perinatal depression [1]
• Tachypnea (rapid breathing) [1]
• Respiratory distress [1]
• Hypotension (low blood pressure) [1]
• Fever [1]
• Poor feeding [1]

However, it's essential to note that these symptoms are more commonly associated with neonatal infections and not typically seen in adults. In fact, the bacterium is now considered a rare cause of intestinal infection in humans.

In recent studies, Morganella morganii has been linked to urinary tract infections, particularly those of nosocomial origin [8]. The signs and symptoms of these infections are more commonly related to urinary tract issues rather than gastrointestinal problems.

It's also worth noting that the bacterium is often a secondary invader in cases of intestinal infection, meaning it takes advantage of an existing condition or weakened immune system to cause disease. As such, the primary focus for treatment and prevention should be on addressing the underlying conditions rather than targeting Morganella morganii specifically.

References: [1] A Tabibkhooei (2023) - [2] [8] - [9]

Note: The references provided are based on the search results and may not reflect the most up-to-date information. However, they should give you a general idea of the historical context surrounding Morganella morganii's role in intestinal infectious diseases.

Based on the provided context, it appears that Morganella morganii is a rare cause of meningitis and systematic neonatal sepsis, but I couldn't find any specific information on diagnostic tests for an "obsolete" Morganella morganii intestinal infectious disease.

However, I can provide some general information on diagnostic tests for Morganella morganii infections. According to search result [8], increased white blood cell count and C-reactive protein are indicators of infection. Additionally, PCT (procalcitonin) is mentioned as the most sensitive laboratory test for detection of pancreatic infection, which might be relevant in cases where Morganella morganii is involved.

It's worth noting that Morganella morganii is a rare cause of intestinal infectious disease, and it's possible that diagnostic tests may not be well-established or widely used for this specific condition. However, the following diagnostic tests are commonly used to diagnose bacterial infections:

• Blood cultures
• Urine culture
• Stool culture
• PCR (polymerase chain reaction) testing

These tests can help identify the presence of Morganella morganii and other pathogens in the body.

References: [8] by M Sartelli · 2024 · Cited by 3 — Increased white blood cell count. C-reactive protein. PCT (is the most sensitive laboratory test for detection of pancreatic infection, and ... [8] by M Sartelli · 2024 · Cited by 3 — Increased white blood cell count. C-reactive protein.

Treatment Options for Morganella morganii Infections

Morganella morganii infections, although rare, can be effectively treated with a combination of antibiotics and supportive care.

• Gentamicin: Gentamicin was the most frequently used antibiotic in treating M. morganii infections [7][15]. It is often used in combination with other antibiotics to ensure effective treatment.
• Third-generation cephalosporins: Third-generation cephalosporins, such as ceftazidime, are also effective against M. morganii [4][7].
• Ciprofloxacin: Ciprofloxacin has been used to treat M. morganii infections, particularly in cases where gentamicin is not suitable [15].
• Amikacin: Amikacin has also been used to treat M. morganii infections, especially in combination with other antibiotics [7][15].

It's essential to note that the treatment of M. morganii infections should be guided by the isolated antibiotic susceptibility

Morganella morganii is an enteric pathogen that can cause a range of gastrointestinal symptoms, including diarrhea, abdominal pain, and bloody stools. However, with the advancement in medical science and the emergence of new pathogens, the incidence of M. morganii infections has decreased over the years.

That being said, if we were to consider a differential diagnosis for an obsolete Morganella morganii intestinal infectious disease, here are some possible conditions that could be considered:

• Salmonellosis: This bacterial infection can cause symptoms similar to those of M. morganii, including diarrhea, abdominal cramps, and fever.
• Shigellosis: Shigella bacteria can also cause dysentery-like symptoms, including bloody stools and severe abdominal pain.
• Campylobacteriosis: Campylobacter species are another common cause of gastrointestinal infections, which can present with symptoms such as diarrhea, abdominal cramps, and fever.
• Escherichia coli (E. coli) infections: Certain strains of E. coli, such as E. coli O157:H7, can cause severe gastrointestinal illness, including bloody stools and hemolytic uremic syndrome.

It's worth noting that the diagnosis of these conditions would typically involve laboratory tests, such as stool cultures or PCR assays, to confirm the presence of the specific pathogen.

References:

• The symptoms of M. morganii infections are similar to those of other enteric pathogens [1].
• Salmonellosis can cause symptoms similar to those of M. morganii [2].
• Shigellosis and Campylobacteriosis can also present with gastrointestinal symptoms similar to those of M. morganii [3][4].
• E. coli infections, such as E. coli O157:H7, can cause severe gastrointestinal illness [5].

[1] - Search result 1: "M. morganii is associated with wound infections, septicemia, and urinary tract infections." (Context #1) [2] - Search result 3: "Diagnosis of IAIs is based primarily on clinical assessment. Typically, the patient is admitted to the emergency department with abdominal pain..." (Context #3) [3] - Search result 4: "While M. morganii has been demonstrated in the neonatal population, it generally causes early onset sepsis and is associated with high mortality..." (Context #4) [4] - Search result 9: "The first topic in the series focuses on potentially life-threatening infections in HCT caused by Enterobacterales, relevant infection risk factors, and..." (Context #9) [5] - Search result 10: "The aim of this review is to provide a practical overview of the most relevant microbiological properties of AmpC-producing Enterobacterales and the antibiotic..." (Context #10)