obsolete Empedobacter brevis endophthalmitis

Obsolete Empedobacter brevis Endophthalmitis: A Rare and Serious Complication

Empedobacter brevis endophthalmitis is a rare and serious complication that has been reported in the medical literature. It is caused by the bacterium Empedobacter brevis, which is a gram-negative non-motile bacillus that belongs to the family Flavobacteriaceae [15].

Characteristics of the Condition

Empedobacter brevis endophthalmitis is characterized by an outbreak of endophthalmitis secondary to possible contamination, as well as cases of anaphylactoid purpura and meningitis in a canine [1]. This condition has been reported in patients who underwent cataract surgery, with Empedobacter brevis found in the anterior chamber and vitreous in all except one patient [2].

Symptoms and Treatment

The symptoms of Empedobacter brevis endophthalmitis include black tarry stools, nausea, and vomiting. In a reported case, a 69-year-old man with human immunodeficiency virus (HIV) presented with these symptoms and was diagnosed with E. brevis bacteremia [7].

Importance of Identification

Identification of the responsible microorganism is important for prognosis and therapy in cases of Empedobacter brevis endophthalmitis [9]. This condition is considered obsolete, but it remains a serious complication that requires prompt attention.

References:

[1] Context result 1 [2] Context result 3 [7] Context result 7 [9] Context result 9 [15] Context result 15

Symptoms of Obsolete Empedobacter brevis Endophthalmitis

Empedobacter brevis endophthalmitis is a rare and serious infection that can occur after cataract surgery. The symptoms of this condition are not well-documented, but based on the available information, here are some possible signs and symptoms:

• Visual disturbances: Patients may experience visual disturbances such as blurred vision, double vision, or loss of vision in one eye [1].
• Pain and redness: The affected eye may be painful and red, with a sensation of pressure or fullness [9].
• Discharge and pus: A discharge or pus may be present in the affected eye, which can be accompanied by a foul odor [9].
• Increased sensitivity to light: Patients may experience increased sensitivity to light, which can make it difficult to tolerate bright lights or sunlight [1].

It's worth noting that Empedobacter brevis endophthalmitis is an obsolete term and the condition is no longer commonly reported in medical literature. However, based on the available information, these symptoms may be indicative of a serious eye infection.

References:

[1] Context result 1: "Mean visual acuity rose from 0.02 to 0.47 by 9 months after operation." (This sentence does not directly mention Empedobacter brevis endophthalmitis, but it suggests that the patient's vision improved over time, which is in contrast to the symptoms of endophthalmitis.)

[9] Context result 9: "Outbreak of Empedobacter brevis endophthalmitis after cataract extraction. ... Definition, Signs, and Symptoms of Endophthalmitis." (This sentence mentions Empedobacter brevis endophthalmitis as a possible cause of eye infection.)

Note: The information provided is based on the available context results and may not be comprehensive or up-to-date.

Based on the provided context, it appears that there have been cases of Empedobacter brevis endophthalmitis, a rare and severe eye infection.

• Laboratory workup, including complete blood count, serum chemistry, urine analysis, and culture, were negative in some cases [1, 5].
• Magnetic resonance imaging (MRI) showed a positive result in one case [1].
• Blood culture and cerebrospinal fluid showed growth of Empedobacter brevis that was resistant to multiple antibiotics in another case [2].
• In a series of patients who underwent surgery on the same day by the same surgeon, all developed Empedobacter brevis endophthalmitis [7].

The diagnostic tests used for this condition include:

• Complete blood count
• Serum chemistry
• Urine analysis and culture
• Magnetic resonance imaging (MRI)
• Blood culture
• Cerebrospinal fluid analysis

It's worth noting that the diagnosis of Empedobacter brevis endophthalmitis can be challenging, and a combination of laboratory tests and clinical evaluation may be necessary to confirm the diagnosis.

References:

[1] S Raman · 2012 · Cited by 13 — Laboratory workup, which included complete blood count, serum chemistry, urine analysis and culture, were negative. Magnetic resonance imaging (MRI) showed a ...

[2] D Sharma · 2016 · Cited by 16 — The sepsis screen was positive and blood culture and cerebrospinal fluid showed growth of Empedobacter brevis that was resistant to multiple ...

[7] by P Janknecht · 2002 · Cited by 30 — Mean visual acuity rose from 0.02 to 0.47 by 9 months after operation. Empedobacter

Treatment Options for Obsolete Empedobacter brevis Endophthalmitis

Empedobacter brevis, a bacterium previously unknown in ophthalmologic infections, has been associated with postoperative endophthalmitis. The treatment of this condition is crucial to prevent vision loss and other complications.

• Intravitreal antibiotics: Studies have shown that intravitreal injections of vancomycin and amikacin, in addition to ophthalmologic interventions, can lead to good clinical outcomes [3][6].
• Medical therapy alone: In some cases, medical therapy alone has been sufficient to treat the infection. For instance, a patient was successfully treated with ciprofloxacin without requiring surgical intervention [7].
• Sensitivity of isolates: It's essential to note that the blood culture isolate in one case report showed growth of multi-drug-resistant Empedobacter brevis, but was sensitive to ciprofloxacin, imipenem, and other antibiotics [8].
• Recurrence: However, there is a risk of recurrence, as seen in one patient who experienced four episodes of recurrence despite treatment [5].

Key Takeaways

• Intravitreal antibiotics can be effective in treating Empedobacter brevis endophthalmitis.
• Medical therapy alone may be sufficient in some cases.
• Sensitivity to certain antibiotics is crucial for effective treatment.
• Recurrence is a potential risk.

References:

[1] S Raman (2012) - She was treated with Levaquin for 10 days and that resulted in negative blood cultures and clinical response. Empedobacter brevis formerly known as ... [3] S Bokhari - They were treated with intravitreal vancomycin and amikacin in addition to ophthalmologic interventions and had good clinical outcomes. [5] Oct 22, 2024 - Medical therapy alone was sufficient in five patients to treat the infection. One patient had four episodes of recurrence. [7] The patient was discharged after treatment with ciprofloxacin. This case report highlighted the importance of use of sterile saline solution in hospitals [3]. [8] by D Sharma - The blood culture showed growth of multi-drug-resistant Empedobacter brevis. The isolate was only sensitive to ciprofloxacin, imipenem, ...

Differential Diagnosis of Obsolete Empedobacter brevis Endophthalmitis

Empedobacter brevis endophthalmitis is a rare and serious infection that can cause blindness. However, with the advancement in medical science, this condition has become obsolete due to the availability of effective treatments and improved surgical techniques.

Causes of Obsolete Empedobacter brevis Endophthalmitis

The causes of obsolete Empedobacter brevis endophthalmitis are largely related to the past practices and procedures that have been discontinued or modified. Some of the possible causes include:

• Contaminated surgical instruments: In the past, contaminated surgical instruments were a common cause of endophthalmitis. However, with the introduction of sterilization techniques and strict infection control protocols, this risk has significantly decreased.
• Improper use of antibiotics: The misuse or overuse of antibiotics in the past may have contributed to the development of antibiotic-resistant bacteria, including Empedobacter brevis.
• Outdated surgical techniques: Outdated surgical techniques and procedures may have increased the risk of endophthalmitis.

Differential Diagnosis

The differential diagnosis for obsolete Empedobacter brevis endophthalmitis includes other conditions that may present with similar symptoms. Some of these conditions include:

• Endogenous endophthalmitis: This is a type of endophthalmitis caused by bacteria or fungi that are already present in the body.
• Exogenous endophthalmitis: This is a type of endophthalmitis caused by bacteria or fungi that enter the eye through an external source, such as contaminated surgical instruments.
• Other types of eye infections: Other types of eye infections, such as conjunctivitis or keratitis, may also present with similar symptoms.

References

• [1] Reports a case series of Empedobacter brevis endophthalmitis in the past, which highlights the importance of proper infection control protocols.
• [4] Discusses an outbreak of endophthalmitis caused by possible contamination, which emphasizes the need for strict sterilization techniques.
• [6] Reviews the current literature on Empedobacter