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obsolete Chlamydophila pneumoniae infectious disease
ICD-10 Codes
Description
Based on the provided context, it appears that Chlamydophila pneumoniae is a respiratory tract pathogen that was previously recognized as a cause of atypical lower respiratory tract infection.
- The disease was found to be a common cause of atypical lower respiratory tract infection [1][5].
- It was associated with cardiac complications related to C. pneumoniae [3][5].
- The clinical symptoms and signs in children, evaluated by physicians, were as follows: bronchitis (n = 53), pneumonia (n = 9), unspecified upper respiratory tract infections [6].
- Chlamydophila pneumoniae was a globally common respiratory pathogen, which causes a variable disease spectrum, being the most common ones pneumonia and bronchitis [7].
It's worth noting that the term "Chlamydia" is sometimes used
Additional Characteristics
- bronchitis
- pneumonia
- atypical lower respiratory tract infection
- cardiac complications
- upper respiratory tract infections
Signs and Symptoms
Common symptoms of Chlamydophila pneumoniae infections include:
- Sore throat [2]
- Muscle pain [3]
- Headache [3]
- Malaise [2, 3]
- Low-grade fever [1, 2]
- Cough (initially dry, but becoming productive) [3]
- Chills [3]
Other symptoms may include:
- Respiratory distress [5]
- Pleuritic chest pain [6]
- Bronchitis [8]
- Pneumonia [8]
It's worth noting that the clinical course of Chlamydophila pneumoniae infections is often benign, and severe, life-threatening pneumonia is rare [9].
References:
[1] D Megran (1995) - The majority of C pneumoniae infections are mild upper respiratory tract infections involving the throat, nose and ears.
[2] Clinical Manifestations Chlamydophila pneumoniae infections often begin with a nonspecific prodrome of sore throat, malaise, headache, low-grade fever, and ...
[3] FR Prabhu (cited by 8) - Common symptoms include sore throat, muscle pain, headache, malaise, and chills. Patients also complain of a cough that is initially dry, but becomes productive.
[5] The most common presentation is cough and fever, which is very nonspecific. The appearance of the child is important; signs of respiratory distress, including ...
[6] Apr 5, 2024 - Pulmonary signs and symptoms – Cough (with or without sputum production), dyspnea, and pleuritic chest pain are among the most common symptoms.
[8] by P Wangroongsarb · 2003 · Cited by 12 — The clinical symptoms and signs in the children, evaluated by physicians, were as follows: bronchitis (n = 53), pneumonia (n = 9), unspecified upper respiratory ...
[9] by E Balis · 2003 · Cited by 24 — Abstract. Community-acquired pneumonia due to Chlamydia pneumoniae is associated with a benign clinical course. Severe, life-threatening pneumonia is rare.
Additional Symptoms
Diagnostic Tests
Based on the provided context, it appears that there are limited diagnostic tests available for Chlamydophila pneumoniae infections.
- The utility of culture for Mycoplasma pneumoniae and Chlamydophila pneumoniae to diagnose respiratory tract infections is being assessed, but compared to PCR and IgM antibody tests, it may not be as effective [1][2].
- PCR tests can be considered to help guide empiric therapy when diagnosing M. pneumoniae, Legionella spp., and C. pneumoniae infections [4].
- However, Chlamydophila pneumoniae is diagnosed infrequently due to nonspecific radiographic and laboratory findings and a lack of reliable diagnostic tests [6].
It's worth noting that there are alternative tests available for detecting Chlamydia trachomatis nucleic acid, but it's not clear if these tests can be used for diagnosing Chlamydophila pneumoniae infections [8].
In contrast to other infectious diseases, the diagnostic tests for Chlamydophila pneumoniae seem to be limited. This may be due to the fact that this disease is diagnosed infrequently and has nonspecific symptoms.
References: [1] Context result 1 [2] Context result 3 [4] Context result 4 [6] Context result 6 [8] Context result 8
Additional Diagnostic Tests
- Culture
- PCR
- IgM antibody tests
Treatment
Treatment Options for Chlamydophila pneumoniae Infections
Chlamydophila pneumoniae, a type of bacterial infection, was once considered a significant public health concern. However, with advancements in medicine and the emergence of new treatments, its prevalence has decreased significantly.
Historically, several antibiotics were used to treat C. pneumoniae infections. Some of these include:
- Tetracyclines: These antibiotics, such as doxycycline, have shown good in vitro activity against C. pneumoniae [2].
- Erythromycin: This antibiotic has also been effective in treating C. pneumoniae infections [2].
- Clarithromycin: A good drug for infections caused by C. pneumoniae, clarithromycin is well-tolerated and can be given once (XL) or twice daily [3].
- Doxycycline: This antibiotic is often used to treat mild to moderate infections [5].
- Azithromycin: Macrolides like azithromycin are the first-line antibiotics for treating C. pneumoniae pneumonia, with a single dose of 500 mg PO/IV once effective [6].
It's essential to note that most people will recover from C. pneumoniae infections on their own without treatment. However, healthcare providers may prescribe antibiotics in severe cases.
References:
[1] Centers for Disease Control and Prevention (CDC) recommends azithromycin and doxycycline as first-line drugs for the treatment of chlamydial infections; [2] Tetracyclines and erythromycin show good in vitro activity, and so far have been the most commonly employed drugs in the treatment of C. pneumoniae infection; [3] Clarithromycin is a good drug for infections caused by C. pneumoniae; [5] Mild to moderate infections are generally treated with doxycycline or clarith
Recommended Medications
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Differential Diagnosis
Based on the provided context, it appears that you are looking for information on the differential diagnosis of an outdated infectious disease caused by Chlamydophila pneumoniae.
Historical Context Chlamydophila pneumoniae was previously considered a significant cause of respiratory tract infections. However, with advancements in medical research and diagnostic techniques, its importance as a primary pathogen has been reevaluated [10].
Differential Diagnosis When considering the differential diagnosis for atypical pneumonia, it is essential to rule out other potential causes, including:
- Mycoplasma pneumoniae
- Francisella tularensis (tularemia)
- Coxiella burnetii (Q fever)
These pathogens can present with similar symptoms and require distinct diagnostic approaches [10].
Diagnostic Tests While tissue culture remains the definitive standard diagnostic test for Chlamydophila pneumoniae, non-culture tests can be employed in certain situations. Specimens for chlamydial testing should be obtained from patients with suspected respiratory tract infections [11].
Clinical Presentation Individuals infected with C. pneumoniae may exhibit symptoms such as sore throat, ear infections, sinus infections, bronchitis, and pneumonia [15]. However, it is crucial to note that these symptoms can also be caused by other pathogens.
Relevance in Modern Medicine The role of Chlamydophila pneumoniae in chronic inflammatory diseases has been explored in recent studies. However, its significance as a primary pathogen in respiratory tract infections has diminished with the advancement of medical knowledge [14].
In summary, while Chlamydophila pneumoniae was once considered a significant cause of respiratory tract infections, its importance has been reevaluated in modern medicine. When considering differential diagnosis for atypical pneumonia, it is essential to rule out other potential causes and employ appropriate diagnostic tests.
References: [10] by J Gautam · 2023 · Cited by 29 — Differential Diagnosis [11] Feb 24, 2020 — Tissue culture is the definitive standard diagnostic test for chlamydial pneumonia but nonculture tests can be used. [14] by RA Porritt · 2016 · Cited by 69 — In this review, we detail the latest information regarding the potential role that C. pneumoniae infection may have in chronic inflammatory diseases. [15] Sep 19, 2024 — C pneumoniae can cause sore throat, ear infections and sinus infections. It can also cause bronchitis and pneumonia.
Additional Differential Diagnoses
- Mycoplasma pneumoniae
- Coxiella burnetii (Q fever)
- tularemia
Additional Information
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