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CEDNIK syndrome

ICD-10 Codes

Related ICD-10:

M87.131 M94.352 F44.8 G43.51 H47.49 I66.29 L94.2 M61.411 N01 N01.4 O08.2 Q73.1 B58.0 M21.27 M41.52 M92.0 T65.3X D72.9 G57.8 H90.A M24.273 M80.85 M87.364 Q24.8 E75.21 G62.81 H71.23 I82.523 M11.05 M46.22 A96 C90.3 H31.1 M00.18 M12.37 H18.8 H18.83 H57.09 I82.71 M06.331 M12.161 M90.59 Q66.82 E75.28 G81.11 G81.12 H02.012 H26.033 K55.01 M87.311 M90.58 Q37.8 Q61.11 S34.12 S34.124 D89.8 G95.8 G95.81 H15.09 H18.523 M00.24 M45.7 M92.52 S25.39 T86.848 C72.4 M84.821 E20.81 E79 H11.019 H18.593 M19.27 Q64.12 Q95.5 C91.6 M05.459 M86.45 M86.451 S43.22 B06.0 D68.318 G04.01 M60.16 M86.342 M86.671 M87.171 S92.25 C79.32 M11.01 M11.1 M12.551 M85.631 M86.8X6 M89.451 M92.21 M92.212 T63.33 C46.1 D57.4 D57.40 M21.75 M62.411 M84.532 M92 D89.44 H11.21 I69.252 M48.8X3 M87.344 M94.8X6 N02.8 H05.26 I73.00 L40.9 L87.9 L93.0 M24.62 M89.51 M93.269 E71.310 E71.518 M84.552 Q72.89 H26.00 H26.009 I69.332 M05.21 C69.32 C4A.9 M08.20 M86.631 P83.2 Q27.34 E13.4 E75.6 G11 G40.834 H02.7 L87 L87.1 M00.25 M62.441 M65.251 M87.28 Q76.7 S34.5 T78.41 G83.1 D80.9 H35.2 M66 N05.1 Q61.8 Z85.038 Z87.728 D81 D81.4 E76.3 H47 I82.56 I82.7 K05.22 K05.222 M11.062 M61.352 M87.238 M93.8 N13.731 S34.0 S34.114 S45.29 T80.219 H31.3 H31.413 H35.44 J84.02 Q75.022 H11.89 H33.032 M89.542 O14.0 A60.02 D37.032 E72.20 H21.222 H47.14 K50.914 M54.05 M60.89 B41 C86.6 D61.89 E75.3 J43.1 M12.17 M47.2 M79.18 Q26.2 Q37 Q37.5 L89.44 L98.8 M87.23 N34 Q60 S60.420 E10.2 H15.021 G90.52 H35.369 S35.49 K51.4 L95.8 M85.619 N48.22 B02.3 C96.0 G03.2 H21.1X1 E80 G32 M61.222 M66.29 M86.36 Z22.341 D80.0 F40.231 L12.1 M08.861 O35.3 Q35.5 Q78.8 S13.16 S13.160 M71.87 M99.1 S92.31 M66.22 M85.9 S06.372 T34.81 E79.8 E79.89 H18.532 H35.171 M50.12 M86.54 M86.622 M89.8X1 Q63.8 E31.20 H05.31 Q60.0 S54.3 G52.3 G56.0 H18.831 H31.00 Q14 Q14.3 S34.121 B02.7 F17.213 H18.333 M05.172 R94.112 A77.2 D68.09 H26.06 I65.21 K50.118 L40.4 M61.169 B30.3 E83.118 M06.09 M84.522 M89.521 E83.8 G57.22 H93.3X M46 M61.571 C79.40 H16.022 N02.0 M87.334 M89.569 H15.022 H80.23 M02.362 M61.10 M86.239 N02.B5 S04 C4A.2 I69.16 M00.141 M41.4 M89.411 E76.22 H30.819 H95.11 I82.C11 M87.033 M87.07 M87.077 M89.55 Q71.0 Q71.01 Q77.6 S52.28 S82.12 C70.1 E85.3 M05.26 M05.261 M11.11 M25.05 P27.0 A56.09 C92.A2 E75.26 G71.02 I30 M92.5 S60.821 G40.01 G95.89 H68.029 L92 M90.51 N07.9 H18.553 M48.10 M61.177 M61.211 M61.542 M83.4 P91.823 S46.1 D81.810 E75.09 G40.814 H53.47 I82.B29 M61.461 M79.81 M92.62 A69 A69.1 E64.2 E71.19 M12.19 M89.8X9 F84.2 H21.25 H21.252 M86.32 M86.322 Q24 G95.0 Q15 T32.40 A77.49 H33.193 I67.83 M42.0 M61.242 M86.679 N52.36 E70.89 H04.813 I63.341 M60.021 M84.871 M86.162 Q45.3 Q92.8 S02 S62.03 T17.900 Z83.438 C44.41 D70.4 G31.9 G56.42 H18.233 H44.0 M12.10 G31.81 G56.13 I63.549 I82.511 M92.40 T32.99 M05.22 M1A.43 M61.262 M93.249 T75.22 A28.2 B25.0 B47.9 D60.1 G92.0 G92.00 H18.549 H35 I82.B21 Q12.4 D81.82 G04.82 H68.123 M62.529 M71.472 D80.3 N99.521 S24.131 T86.2 G12.21 L66.3 M35 M35.6 M46.89 M66.2 M87.177 N02.4 E13.36 H57 I82.3 K13.4 M00.11 M47.014 M61.219 M61.45 M86.219 Q21.14 Z22.340 H18.13 H26.003 L97.314 M05.371 M12.44 M79.64 M86.532 M86.612 Q25.4 S14.113 C37 H61.01 M54.04 S15.09 C85.2 G43.6 G43.61 H05.243 H16.141 H71.2 I97.82 M84.52 N29 P37.9 C88.21 G31.8 G31.85 G80.3 H02.14 H04.011 H92 M07.612 M35.0 M43.8X5 Q91.5 Z15 Z87.738 B38.0 D89.42 E75.24 E75.249 H25.81 H74.31 J84.8 J84.82 M02.80 M65.252 M84.51 Q44.71 T56.4 T86.298 E70.40 G93.43 H18.231 H26.03 H26.032 I69.262 L66.11 M06.35 M06.372 M61.439 M86.53 M87.029 M89.03 M89.031 M89.44 N04.29 S52.2 H31.8 M11.04 M34.81 M87.111 M87.81 M87.811 Q25 S93.13 G40.A09 G65.0 H02.72 M60.04 M61.4 Q71.41 A30.1 A69.22 A84.1 C70.9 D89 G37.4 H02.51 I79.1 M14.68 M61.2 M61.21 M61.469 Q56 E20.810 H02.01 H18.443 H31.303 H36.82 M11.84 Q92.0 S14.151 S83.13 T45.615 G96.08 H35.732 M86.43 P19.2 S35.299 A50.51 B57.31 C81.42 D81.819 E78.72 G61.81 H61.033 S13.1 Z87.72 H02.141 M12.149 M60.042 M61.1 M61.15 M87.037 M92.503 Q43.3 D47.Z2 E20.811 E71.521 H15.84 H15.843 M61.04 M62.8 Q71.52 R94.1 C90.30 D48.117 I77.4 M05.69 M12.112 M12.411 B25 D59.5 G44.03 K55.3 M02.371 M05.20 M12.16 M87.0 D59.1 D59.12 E75.19 H50.08 I69.32 I69.321 N80.562 D84.1 E10.36 H30.113 M32.8 C84.A H21.81 J63.2 M61.451 M62.449 M99.31 N07 N07.8 P77 Q71.4 R48.3 H26.113 H35.02 K14.2 M00.03 M12.141 M86.05 C84.A9 E70.81 G90.5 H15.043 I69.992 M25.832 M86.021 M86.061 M86.651 M89.167 Q68.0 D50.1 H16.40 H16.403 H22 H31.301 M99.26 N07.7 Q93.5 Q93.52 S34.129 G11.1 H18.45 K90.49 M02.351 M61.131 M86.12 M86.122 M86.57 M86.579 Q71.53 A39.3 H02.519 H83.91 I69.313 M06.371 M61.25 P35.9 E10.620 H18.323 M12.46 M24.52 M60.86 G12.8 H68.00 H80.83 I22.0 M84.869 M89.15 P72.8 G93.1 I82.A M34 M61.3 M87.034 Q78.0 C4A H53.63 H54.61 C47.9 D70.1 E23 H80.8 M04.2 M12.1 M12.11 M89.2 Q98 S64.1 Z85.44 C92.0 G12.2 G90.0 K22.89 S80.829 T32.31 C7A.091 E75.23 E79.82 H15.052 M02.34 M08.411 M42.19 Z84.1 H80.20 M70.03 M87.237 M89.04 M89.549 M89.731 T34.531 H82.1 M11.041 M12.031 M60.17 S42.03 H36.823 M61.212 M92.51 N03.2 C46.52 H02.511 M34.2 M89.059 M89.45 Q70.4 E70.32 E70.49 E74.39 I69.828 M24.07 M24.075 M26.633 M89.8X Q40.8 H21.532 J93.1 N07.6 A43.8 C92.6 E31.23 G04.3 H20.04 M11.08 M11.132 M88.812 P09.2 T79.1 G58.8 H30.893 H35.52 I82.5Y L91.9 M11.239 M24.47 M41.114 Q87.84 R11.15 T26.5 T26.52 C84.19 D36.0 G11.11 G24.2 H11.4 H50.81 K51.3 K83.4 M61.049 Q61.5 Q79.62 B37.81 C86.3 H17 K86.89 M87.022 E13.59 M65.23 M89.13 S60.32 E07.0 M99.7 Q31.8 T32.97 T83.21 G57.4 I39 M46.2 M87.339 Q77 S52.01 G90.9 H26.33 M48.1 M86.351 N18 D69.4 D69.42 E78.81 H83.8X1 I78 I78.8 M05.842 Q16.4 Z90.710 D36.1 E75.240 G70.8 H05.02 H18.512 H20.2 H83 M85.46 M87.819 O35.11 S12.0 A75.3 H44.2D H44.2D2 M07.69 M43.8X M61.0 M61.07 Q30.2 E67.2 E71.50 G00.2 L13.0 M12.441 Q79.61 T32.30 E72.59 G25.7 H35.723 H68.12 H74.329 K05.20 L57.3 L98.414 M07.6 M26.70 M32.12 N26.9 S35.298 A19.8 C96.5 H40.242 M87.031 M87.873 S14.102 E13.2 M62.44 N18.32 Q87.81 H02.433 H18.601 M12.09 M61.112 M87.221 C62.0 I69.319 M00.252 Q71.89 Q74 Q74.8 A84.8 E61.2 I69.292 M02.38 M42.09 M92.6 Q18 S11.25 T86.3 G23.3 H10.519 H21.35 M61.139 N02.A S14.155 D59.11 H18.622 H53.13 H80.1 I77 I78.9 M86.449 M89.74 B08.6 H21.223 M05.3 M86.42 M86.422 R29.81 D69.1 E71.41 H35.3 H40.232 H91.20 M89.06 M89.062 M93.272 M12.131 H40.221 L98.493 M11.172 M93.83 Q66.81 H18.513 M61.232 E78.71 M87.838 M87.864 Q39.8 A81.01 H35.173 M86.249 S90.423 E72.23 G99.2 M00.14 M1A.49 M89.70 P57 P57.0 Q87.85 E21 H35.353 K50.018 C75.2 M62.471 M87.13 T34.62 C86.1 M48.18 M87.377 M89.77 M89.771 Q33.0 D72.820 E71.311 L74 M11.031 M61.13 M87.83 Z89 C69.4 C69.41 G92.05 H68.021 Q14.1 Q39 G40.42 M12.36 M60.06 M61.272 A48.4 G81.01 H20.23 M46.93 N03.5 Q82.3 A39.2 C81.0 M02.36 M24.27 Q78.3 H11.223 H68.02 N02.1 D57.434 E75.241 H16.259 L57.4 M02.331 M80.871 N11.9 P37 C90 M86.459 Q63.9 Q87.5 I69.215 M12.0 H21.22 H21.229 K90.81 Q77.8 H18.12 H35.33 M61.522 N01.1 T84.39 D57.454 H30.81 H30.812 H93.3X9 T63.334 C40.8 G40.4 G60.3 G31.86 H05.822 Q87.82 H15.852 H42 M62.23 M86.46 D70.0 I66.03 M65.26 S14.156 C91.5 G51.2 G71.032 H90.1 M62.43 M70.21 M87.079 C46 C46.0 C81.3 D75.822 G60 Q06.8 C79.51 M60.071 N02.6 E70.320 G47.35 H70.2 M89.439 S52.62 T86.00 D68.2 H35.5 J84.112 M86.221 A66.5 N80.3B3 D76 H02.23 I63.441 L97.22 M11.20 M65.0 M87.035 M92.1 M92.10 D86.82 G43.60 E75.5 J84.114 M84.58 M88.861 M89.7 O35.13 R94.4 H59.09 M45.6 H15.042 M62.252 P11.2 S90.521 T32.88 E70.29 E70.328 H04.022 M60.111 M84.65 M89.56 S13.12 A50.52 K12 M02.349 M61.46 M62.561 M86.042 O35.14 H60.32 M11.171 M87.85 Q43 Q93.0 D59.13 E71.313 H26.061 M96.89 N07.3 G47.421 H31.121 M71.4 M86.61 B10.09 C84.10 E71.111 M05.422 M87.865 H35.023 H40.063 M24.569 S01.151 C46.4 M48.8X2 M65.2 M86.252 N04.3 N96 D57.819 G71.0341 K04.3 M05.251 M25.6 M61.541 M86.159 M90.542 S23.14 S64 E77 E77.9 G71.0340 H35.8 I26.04 I67.7 T86.90 C84.1 C84.16 D57.2 D57.20 D81.31 G05.4 H16.021 H31.10 H36.81 I69.26 I82.5 L13.1 M12.171 M61.26 M84.755 C86.4 D58 H18.501 H18.53 H18.531 H18.54 I82.51 L90.0 M12.07 M12.072 M41.40 D72 E74.1 E74.10 H05.021 H16.05 H16.059 H18.319 H91.23 M23.31 M86.15 M89.52 M89.522 S34.11 I69.36 I69.369 L74.4 L97.30 M25.075 M67.8 S74 A66.6 E10.61 E32.8 H05.1 H47.4 H61.02 H61.021 L87.8 M05.27 M06.32 M86.112 T86.8403 E06.2 E26.02 M02.35 M61.562 M84.611 M87.363 Q61.1 Q61.19 R29.90 A83.4 G54.5 M84.8 Q71.5 G40.84 G40.841 M33.11 M84.832 M87.25 M87.338 Q73 M87.222 Q71 R83.3 T82.83 G04.32 H02.015 H16.011 M46.91 M89.421 M89.46 O26.4 P28.2 E74.19 E75.1 E75.11 H34.9 I67.850 I69.253 I69.254 L10 M47.0 M61.173 S04.3 H31.312 H47.211 M00.042 M26.10 M92.59 N52.01 Q61 E71.2 E76.210 E76.211 M05.36 M15 M30.3 M46.8 M86.211 S52.09 S52.092 A32.11 A67.2 G11.19 G72 H18.551 I82.72 M08.87 M45.1 M47.02 M93.1 S42.1 H02.21A H18.4 H18.43 I80.1 M61.231 M95.4 T36.4X5 H11.41 H11.413 H31.9 L97.323 M89.162 M93.26 N14.11 S06.37 T34.41 E88.3 H95.13 M02.831 M24.276 M61.142 M84.661 M87.842 Q61.9 S14.116 C88.2 E71.3 H31.20 I77.7 M86.14 M87.076 M87.36 Q26 E76.21 G51.3 G51.32 I82.55 M05.152 M71.432 M86.142 H04.42 H90.A1 M11.8 M34.0 T42.1X5 C46.9 G32.0 M89.161 S50.321 Z85.50 G23.9 M24.219 M24.652 M61.11 M65.232 M89.562 Q87.89 H11.023 M86.619 S43.2 H30.14 I65.0 T84.624 H20.82 H21.313 H35.412 I82.559 M87 M89.53 S50.821 B06.00 D81.2 H02.112 I75.029 M12.8 D48.114 M05.419 M86.241 M86.551 T32.10 Q41 Q41.2 S06.386 B83.2 H18.3 I69.362 I82.541 J67.9 Z16.34 G92.01 K50.10 M53.2X1 M86.20 M91.12 Q71.02 E88.02 L66.9 M12.05 M12.062 M86.272 H50.611 F78.A H15.001 K55.051 M05.84 M24.249 M86.559 Q82 A77.40 H11.22 H53.132 M24.675 M62.462 M86.352 E75.0 H04.023 Z82.79 H35.352 H95.132 M11.051 Q85.89 T32.92 T84.622 G98 G98.8 M91.1 M35.05 M84.56 H05.411 H17.8 H17.82 M06 M06.339 M86.02 M90.57 Q93.7 B06.82 C4A.39 M25.272 M60.151 M84 M1A.42 M61.429 E24.0 G23.0 G24.1 M86.64 A44.1 D35.5 H16.142 L40.5 C83.13 H30.123 H44.531 M60.12 E70.33 E70.330 E76.02 H53.433 Q92.9 Q81 S74.21 H18.629 M31.5 A24.2 B33.20 D81.6 H18.032 Z85.20 E72.1 H04.121 I82.C21 M72.6 M87.032 G50 H01.125 I82.C23 L66 L66.4 G92.8 H18.46 N02.3 H18.503 H66.016 M08.431 M61.239 S34.101 M11.09 M91.81 A42.82 G44.52 H18.22 H26.013 M79.11 M87.05 M87.059 D61.09 H71.02 A44 J38.0 M12.831 M61.121 M85.061 M86.552 M87.08 O69.3 S13.150 H83.8X M24.622 S14.5 M61.29 B38.4 H60.20 M12.13 M85.67 H81.03 I61.6 M61.552 S02.8 M12.172 M84.572 M99.71 H15.031 H40.819 L90.3 M87.044 P96.0 Q64.70 E72.0 K04.4 M89.761 H16.43 M62.552 M86.359 M89.732 Q98.8 G40.0 M84.861 M87.874 B01.1 E71.43 K08.23 A77 C86.30 E85.2 Q81.1 G71.12 K08.22 M84.621 G60.1 H16.402 M02.379 Z90.71 C72.50 M86.642 M87.15 M87.150 M90.562 Q37.9 B96.1 E71.44 M89.752 S14.115 T34.42 D57.42 M08 M53.2X8 M61.241 M84.632 M87.038 N35.812 D57.214 H65.4 M61.42 M66.221 D68.1 E72.21 G37.81 M87.863 D81.81 M05.231 M86.169 M91.10 E20.818 G72.41 H47.313 M65.22 Q38.4 D86.81 H16.3 M90.549 S14.158 B37.89 M30.8 M93.821 B08.09 C96.29 H47.22 M05.81 M05.819 M11.18 M84.669 M89.061 M99.42 A50.53 B08.62 E71.520 Q67.1 S24.151 D31.32 K50.813 M41.22 G12.25 L40.2 L70.2 H02.212 M62.419 Z16.24 H80.93 M46.06 M61.012 M86.161 Q26.9 T56.4X4 C4A.30 E80.0 G90.59 M99.21 R40.211 H80.10 M61.441 M89.251 M89.41 M89.419 M90.531 Q70.11 D57.44 G43.611 Q07 Q55.7 G90.522 M47.015 M47.021 Q80 Q80.1 M05.861 Q65.02 R83.4 C71.2 M12.12 O14.2 P56.90 Q71.2 Q71.21 Q91.0 Q96.2 C26.9 E88.41 H21.5 H34.211 H71.20 N03.3 Z92.26 E71.4 G50.9 H16.203 H40.21 J96.02 M50.02 M86.8X4 M93.89 N05.5 H21.219 M02.3 M87.343 M93.28 R29.70 S30.822 I63.40 M12.45 M99.48 S94.0 T34.511 P25.8 A50.56 D75.89 G11.3 K51.41 M86.25 M90.532 M92.72 M93.22 R46.4 B27.11 I82.593 M92.513 G40.B09 H44.2D3 H61.023 M66.239 M86.319 S13.181 T38.3 C69.11 C96.Z G57.7 Q77.4 R20 I66.13 M86.3 M86.37 D57.433 E32.0 H21.1 Q87.8 G40.10 I63.512 M24.51 N05.A S35.292 C86.2 G71.01 H02.114 H05.412 C81.45 G40.C1 G40.C19 H04.811 H30.13 L59 M61.59 M89.47 Q64.31 A69.29 C81.34 S70.22 T42 H59.099 I69.820 M87.071 Z87.732 E72 H59.023 H66.2 M88.862 H18.712 H35.72 M84.822 M86.01 M61.58 Q65.82 Q75.04 D47.09 G61.1 I82.533 I82.539 T45.4X5 T63.413 B55.0 C88.30 M84.85 G73 M84.834 M87.82 R62.59 S82.3 C75.4 E88.01 G36.8 G56.03 I82.549 M33.19 M86.641 M90.571 B48.0 E71.529 H02.115 M61.261 M87.159 H40.2 H40.22 E71.11 H31.41 M61.41 M67.942 M93.851 S73.04 T34.521 C46.7 C84.11 C86.31 H80.13 M12.87 T56.3X1 A84.9 C86.50 D57.453 G45.1 H44.429 L40.59 M00.061 Q04.1 D68.4 G71.034 M93.0 B34.1 J34.81 M31.9 M61.452 M84.551 Z79.620 I71.01 M05.271 M50.03 M86.17 S23.160 H02.512 H18.89 L65.8 L87.2 M24.139 T80.310 A02.24 E71.440 N01.A R79.0 H35.43 M86.69 M87.375 N07.A S23.122 D57.452 K12.39 M84.862 M86.51 M86.511 M88.1 P37.8 M86.452 H53.462 M24.672 M79.A9 Q27.2 E56.0 H35.022 H47.292 H18.462 H21.2 H81.01 C47.8 J84.170 M62.49 E13.618 M48.8 T34.82 M11.831 M94.8 G90.523 N03.A T32.41 M86.33 N52.37 M60.161 M61.521 M93.861 Q00.1 E71.118 E71.548 H02.854 M53.2X4 M87.02 I69.290 M04 M26.613 M87.062 M87.172 K50.819 M61.022 M87.14 A39.4 E89.8 M27.2 M89.712 Q05.8 S52.00 T84.625 E72.9 H35.73 L66.1 K56.5 M89.261 M05.721 C85.95 E29 T84.59 I70.518 M42.06 C4A.21 E83.0 G90.B M93.279 Q62 M41.83 M61.50 N07.5 Q76.8 G95.19 M62.9 N31.0 I82.451 M54.02 Q82.8 C26.1 H16.323 N80.532 D81.7 I69.834 Q66.1 L89.41 S34.02 M90.50 P91.829 Q41.1 M06.332 M87.175 M35.00 M71.351 M89.722 H04.02 J82.81 M61.269 M88.851 M91.80 R27.0 R60.1 H05.322 H55.09 M05.222 M11.25 M24.651 A88.0 M84.531 M88.82 S90.422 T86.8492 I69.86 G57.63 H68.023 N07.2 D82.9 D89.834 M05.53 M05.77 M61.9 Q07.9 Q72.5 S22.06 C86 D46.A M67.932 Q79.69 S94.00 H18.52 H50.811 L89.43 M87.26 Q90.2 Q91.7 A69.0 E74.820 H02.04 H02.041 M05.241 M11.011 M25.031 M31.8 M89.721 N25 N80.512 H66.3X H81.0 M05.542 M62.47 M87.274 H11.1 H59.093 O35.12 R94.0 S15.12 S24.111 S44.40 E10.A2 E50.3 G32.81 M67.94 M84.561 M87.174 M90.521 Q10.7 D81.39 H30.022 I63.21 I69.951 L89.516 M24.676 P61.4 A04.71 H53.41 H53.413 K06 M60.152 H95.0 H95.02 I06 J84.81 M12.119 M67.86 B30.1 D58.2 D89.1 H35.383 M27.3 S13.111 C79.49 E74.810 H18.221 I78.0 M13.87 S52.091 C4A.8 E00.1 E72.04 H35.17 H82.9 M24.66 M87.861 M89.54 Q06 Q06.1 B38 H18.02 T36.2X T86.899 A50.31 D64.3 D84.8 E13.610 I69.33 I82.221 E71.128 H70.203 K13.23 M05.461 M62.412 M84.619 S34.01 A77.41 H18.541 M47.01 M47.011 L72.1 L74.8 R15.9 Q12.1 Q75.03 G30.1 N03.6 Q75.05 T83.62 D46.22 G90.3 M12.03 M12.079 M61.143 M86.149 Q72.02 D89.810 F78.A1 K05.2 K05.21 M1A.09 Q90.1 G40.844 I49.3 M47.13 E74.05 G54 H04.81 H93.3 Z15.1 D51.1 D82.8 M89.165 F17.298 M61.512 M12.129 M94.8X7 Q80.3 L59.8 N25.1 D57.431 G37.0 H80.9 I82.0 Q50.3 D55.21 I27.1 I63.339 L95 M60.172 P91.81 H95.01 M93.841 M61.421 M89.8X0 Q75.041 H05.41 H16.31 H18.502 G83.5 M61.122 M93.879 G40.842 H02.422 H02.21C H16.39 Q91.2 T37.0X5 B92 D82.0 H18.71 T83.51 H15.051 M80.811 H33.40 Q83.0 Q93.9 A96.8 M11.2 M61.039 T34.71 B02.39 B38.7 D57.43 G44.09 H71.13 L89.42 M05.279 M86.8X3 Q89.0 I63.34 N80.3B1 Q16.3 H18.592 I63.13 D60.9 M49.83 H57.05 M87.21 B27.02 H26.039 J43.0 P09.5 F02.B G90.512 M24.274 N01.9 B00.3 E83.30 G92.03 H15.059 D68.023 M21.371 Q79.59 A30.0 H54.1224 S13.180 H18.30 E75.00 M86.011 P93.0 M06.80 M87.064 S06.1X6 N03.9 E72.50 G93.2 M61.252 Q68.4 M62.5A0 M89.039 D46.C D75.828 H34.812 S00.22 C71.5 D68.312 K06.011 M24.241 E83.31 H21.1X3 E72.01 M86.10 H31.129 D81.5 H53.52 M61.431 M86.58 E72.02 M87.036 Q87.3 I69.353 M25.61 D84.9 H80.21 R07.81 E71.522 G40.843 M00.13 T82.6 M86.372 G24.09 Q87.86 Z16.342 M02.879 G57.71 G44.031 M05.532 M89.49 M87.012 E89.6 M87.859 L98.413 M86.462 D57.219 M66.341 G40.C L89.136 M87.821 M87.850 G71.21 M87.078 M87.12 Q81.2 R62.50 M60.002 S62.0 M12.111 C4A.62 G73.1 I63.011 I69.210 M87.352 M93.229 C81.37 G37.8 L11.0 L12 L66.0 L73.0 M05.642 M61.47 M62.231 T34.821 D75.8 I82.B23 D81.9 H18.332 H35.51 I63.343 M53.88 M61.531 M66.33 Q87.2 T38.3X D57.45 E88.0 H35.22 M05.4 M05.40 M46.05 M61.152 M89.539 Q44.7 Q62.3 Q62.31 S04.62 B08.72 H02.11 H18.312 H26.0 H26.22 H35.051 L97.223 M61.071 Q99 S14.117 T56.3X4 G56.3 M71.45 M71.451 M86.369 Q85.03 Z89.0 D31.30 D75.82 G71.033 H59.033 Q66.0 S64.0 B27.0 K50.01 K50.011 M89.4 Q51.82 Q71.8 Z87.61 D89.4 H90.11 I80.241 M05.239 M30 Q55.1 M12.312 M87.834 M92.201 Q44.70 Q67.4 C46.51 H80.02 M05.851 M21.5 M50.82 M84.86 B38.3 E70.4 M88.84 Q28.9 H02.42 H02.423 I69.219 M11.22 M11.229 T32.72 E79.1 I02 I69.93 T83.590 T86.23 T87.89 M24.532 Q37.1 S14.157 A40.3 K06.013 Q21.19 D89.2 I31.8 S00.52 H74.313 A96.9 H16.413 I69.939 M11.271 M87.373 E00 E00.0 I69.392 S22.42 H26.063 H28 H80.0 H80.00 M11.061 A30.8 C81.40 D76.3 Q91.4 Z87.74 H18.463 N30.10 B78.7 G25.4 H59.01 I69.965 L66.2 Q99.9 I69.30 H49.2 M87.137 E04.2 D19.1 H16.053 M71.439 M92.31 M71.43 M87.31 M25.50 O26.40 B27.01 C85.29 H80.12 H83.8X3 M89.742 B47 H44.533 G51.33 M12.53 D70.2 A81.82 H18.791 H26.042 L10.9 Q16.5 R82.992 A36.84 H33.052 J84.89 H31.22 I63.513 M05.212 H81.02 M61.27 N05.3 M89.519 H26.062 H16.121 H33.041 H47.231 H60.2 M02.342 H26.04 L53.8 M62.451 M92.522 Q64.33 T82.817 H15.099 H16.322 M08.1 M90.551 E79.9 Q36.1 M89.48 R41.4 T39.095 Z16.35 E20.812 S52.281 A84.0 H11.011 H16.252 M86.16 C4A.121 H26.031 M41.05 H20.823 M61.249 M93.259 S04.31 H30.129 M84.441 B02.33 H80.82 I87.312 M02.819 T36.2X5 G37.5 H35.443 H57.03 L97.823 H40.142 L44.4 C4A.1 I63.31 Q32 S00.421 M12.47 M24.632 M35.0C A17.89 H30.121 H49.23 Q71.20 S83.14 H18.522 I30.8 M41.123 H74.323 H90.5 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M00.01 C84.45 A50.5 M99.32 Q72.811 M87.836 S14.123 K05.223 K50.013 S14.0 M61.56 M86.361 S62.390 G40.813 I63.112 M87.135 M02.311 M11.262 M71.42 D57.458 E72.19 D86.3 G37 M46.88 M94.359 C71.8 M60.132 M05.56 M24.541 M84.639 M86.23 M86.34 M94.3 N02.5 Z16.11 M67.814 S12.15 D68.51 H30.811 I12.0 M61.351 M61.551 L97.213 D83.1 Q31.1 S24.152 E71.448 K83.5 L51.2 M50.33 O45.023 D82.2 G56.12 Q61.02 A56.1 H02.822 L98.5 T38.0X5 H05.231 M87.265 M87.379 M99.41 H16.262 H53.412 L85.8 M05.742 M40.14 H35.729 I67.841 I99 M35.4 M61.062 M93.271 D44.6 E71.42 M06.362 M89.166 M86.13 E20.89 H15.033 H21.8 M08.071 H16.442 E72.53 Q75.5 M06.31 H11.111 H15.091 M86.41 M61.511 M89.71 G36.9 H18.552 M61.519 Q78.6 M87.061 D78.01 E71.0 G90.521 I82.552 L62 M99.33 M11.112 M89.00 M60.131 T86.31 M86.371 H26.049 M61.174 B46.3 B34.3 M93.241 M26.09 T85.738 T36.1X5 Q43.8 M61.132 C44.520 T84.023 M02.321 M86.31 P09.1 H31.23 J15.7 O45.021 K55.8 H53.31 E71.541 H16.269 G71.11 G13.1 L40.51 M93.252 I63.113 E78.89 B45.8 M60.011 D80.4 E78.8 J38.02 M86.072 T34.532 M61.54 D89.811 M62.521 H40.213 M86.522 H44.2C1 I63.323 H10.513 G40.803 H18.521 M31.6 M84.851 M33.92 M86.39 M61.251 A81.81 C72.0 E70.338 M11.152 M87.835 H52.512 I87.032 L98.424 R71.8 H47.293 N02.9 M00.00 T44.0X1 H31.411 C72.2 D48.111 M61.171 T34.812 G40.812 K52.838 M61.549 M11.231 M87.839 H21.211 N01.2 C4A.31 C81.48 M89.59 S14.135 E85.81 Q64.32 M61.175 M12.861 E75.01 M86.062 T86.8422 G25.82 C72.41 H16.412 G31.89 M84.462 G90.1 I82.542 R19.03 M89.032 M12.9 C62.02 H04.033 Q93.4 M36.2 M61.146 H35.029 C34.8 G20.B2 H60.22 M41.02 M89.371 S82.126 Q75.1 M86.35 Q76.412 C49.9 M61.259 H10.529 O45.011 C91.A A42.1 M99.46 T87.34 D43.4 H16.443 K80.11 M24.662 L10.89 L12.2 Q85.81 H52.523 D00.03 M02.312 M60.162 M86.321 M87.180 D86.83 M43.5X8 T34.839 I69.114 H30.813 E10.52 H18.003 H44.2A3 M87.250 M62.442 I82.A22 Q80.4 D80.2 A24.1 M89.741 M93.219 N07.1 I82.441 M88.831 H05.032 E70.311 H04.213 H05.012 M94 B10.82 H66.23 D89.82 I82.543 M1A.459 M31.2 M90.572 B46.4 M84.571 T56.3 E24.3 M61.271 H02.044 M86.331 Q32.1 H17.11 Q77.9 Z15.03 M41.45 D86.85 M46.28 H16.253 M86.531 T86.92 C81.49 M11.861 Q07.00 K80.67 M61.35 Q71.03 H35.322 M86.262 N00.6 L12.35 N18.30 H34.81 M89.751 H16.433 B27.91 M87.361 E79.2 T80.3 M89.011 M99.66 H74.8X2 H61.022 I63.313 B42.1 M00.131 M90.511 M42.03 M85.851 E76.8 Q37.0 G21.8 T37.1X5 M61.371 S14.138 I74.8 M61.23 K06.021 K50.111 M92.599 I82.513 J84.843 C08.1 M90.55 M99.60 M50.13 M87.342 M87.879 I63.349 Q92.1 G65.2 N01.5 M86.132 R83.9 T43.015 J70.1 E71.314 M24.649 M89.422 T42.2X5 T83.591 M71.452 C92.A1 D81.30 T56.3X3 H26.069 M71.431 H15.023 M92.592 D51.0 C69.40 M84.529 M12.59 M61.28 S14.126 M25.03 H60.21 C69.42 Q55.4 B43.2 M05.431 M48.33 D55.0 T84.398 H05.321 M06.1 M08.841 A79.81 O45.029 A50.39 M12.531 H80.01 M89.259 Q78.1 Q85 T86.8402 M86.572 Q72.32 M84.553 M90.541 M93.222 H16.393 M99.68 S86.092 L12.30 T86.859 A51.44 K13.24 K74.01 M06.821 D57.438 C81.32 E56.9 H26.223 I74.9 O45.02 H11.043 I82.562 M35.2 M87.16 Q76.49 T86.91 C4A.4 H18.613 H46.1 H91.03 M24.59 M87.151 Q67.7 M00.21 M87.24 M87.242 Q26.8 H44.41 G90.519 H30.12 I69.35 M61.331 I63.52 M62.830 C46.50 C86.5 H40.14 H40.143 M02.332 M61.05 M89.50 S13.151 E71.52 H04.013 H31.2 L90.4 M86.621 M87.376 Q13.0 B41.7 H18.722 H83.8X2 M06.4 Q23.8 S14.112 M60.13 N03.4 C44.32 H18.321 Q66.89 B06.09 D89.835 G58.7 H59.03 I63.02 S23.11 A36.83 E31.8 H70.20 M86.38 A44.0 L94.4 M24.67 M85.431 N02 Q72.03 D48.19 D81.818 K80.37 L97.504 C86.60 Z15.81 B97.5 H35.42 H35.422 L11.8 M67.853 S14.149 H34.1 J13 L85.2 Q93.3 H18.811 H20.21 M05.411 T82.867 A69.8 H10.511 H18.31 M60.073 M89.739 G44.04 H02.725 I82.891 Q05.1 H16.263 H81.10 M35.09 H31.122 H33.031 M85.661 S25.19 T86.39 C93.9 I87.323 M87.335 T85.733 D81.32 E74.82 H21.243 L57.2 N02.B3 E70.321 M89.479 M90.519 Q91.1 R89.4 M43.8X3 M86.44 G51.31 G90.50 Q12.8 D57.818 M21.221 T34.519 T50.Z15 Z16.22 I49.2 M35.08 E72.89 M25.039 M86.67 M11.822 T34.51 E70.9 I69.220 M86.329 G50.0 H47.291 I69.92 M42.01 G11.8 I73.1 M67.89 D71 L89.156 E76.0 E76.01 I63.322 T32.77 B02.0 G25.69 M05.531 M24.65 M85.632 Q71.899 Q93.59 F95.1 M06.34 M86.172 M86.65 N15.8 E83.39 N02.B1 N02.B9 M41.86 M60.9 T34.90 C84.17 J01.11 M87.043 N05.6 K86.1 Z15.0 H26.053 M87.112 R90.82 Z15.02 G51.9 H02.821 M35.07 O26.42 H18.322 M02.87 I66.23 I82.211 H35.41 M62.551 H59.031 M84.672 C78.80 E71.12 M61.372 I82.592 M61.16 S04.04 I82.531 M86.632 S14.114 G37.2 G71 G70.9 H26.21 M61.17 D72.12 H61.039 H16.051 M1A.29 M53.2X6 M88.871 Q63.1 K05.213 T32.80 N00.A L66.81 M89.552 N01.7 M00.19 C84.18 H61.012 M84.431 B37.6 M05.472 T80.A10 I63.212 M13.14 L66.19 M84.622 E83.09 H18.511 I51.81 I69.998 I66.21 S13.171 M99.38 H15.032 M61.178 E74.01 M61.40 E71.540 M61.162 G96.89 M12.032 M71.33 N28.8 C81.31 H18.453 M89.76 T84.038 M26.53 M62.432 M89.73 M93.862 B08.0 M89.471 S23.120 M11.10 Q25.1 M11.032 E72.52 M08.831 E83.00 M61.229 S34.125 N00.2 H25.813 M43.4 Q64.5 D59.19 E74.31 M89.772 C46.3 H18.029 M84.864 E70.8 M31.19 M86.49 H18.839 H17.89 H21.221 B08.02 A21.0 I63.133 G56.43 S24.0 S27.412 Z86.51 M46.33 M60.051 M86.311 N81.83 R94.128 H30.131 H90.6 T32.85 G72.89 I45.8 M89.042 S90.822 H18.542 M84.758 T84.613 Q18.0 L97.313 M34.1 I26.09 M86.439 M88.0 H17.823 C47.0 H05.112 M71.46 D57.09 M12.052 D57.00 M60.009 M91.82 E45 I63.321 M67.01 H02.23C T85.730 I87.01 M87.877 T32.70 E74.9 H80.11 K51.013 M89.021 I69.990 M89.571 M89.432 Q32.3 Q71.812 M43.8X2 H18.609 S13.14 M88.83 I69.069 M61.39 M87.372 G90.513 E89.40 P80.0 H35.21 M12.08 M92.7 M12.3 M71.421 B46.8 M67.864 M61.161 H11.249 D72.81 E72.22 L94.8 S32.599 H81.8 Q75.08 Q96.3 S00.32 S06.1X7 H73.09 M89.34 S14.106 M24.631 E80.29 M94.351 M60.062 M89.160 A36.82 N01.6 G57.70 N01.8 I63.533 I69.361 S02.19 D55.8 H15.853 K05.313 P09.4 M86.56 I77.810 M86.141 N06.3 R94.13 G11.9 M90.679 D81.1 T34.53 M67.833 M89.511 M61.02 M86.259 M05.652 M31.31 M89.529 A81.89 B38.89 S14.152 M42.08 R26.2 H93.3X3 M86.639 E70.5 D81.0 M87.837 L10.3 H17.13 C84.14 I63.433 G90.09 L94.5 N52.03 T80.218 M05.731 H02.011 Q51.8 T34.522 E71.53 M43.5X5 S13.131 M84.471 M87.132 S24.132 D84.0 P58.8 E32.9 G57.90 M11.28 I63.522 H35.359 C04.8 M14.631 A60.1 I63.432 M86.412 M87.09 I63.39 M61.052 M12.539 E80.1 G40.B01 Q91.6 H30.112 G82.51 I66.2 C84.40 E83.2 J84.111 D33.3 D78.31 M61.172 D68.03 I66.3 M87.843 L90.8 D89.9 H01.134 M11.131 C84.A5 M26.652 H40.212 E85.89 Q37.3 L12.9 M00.28 E75.27 Q96.4 M14.65 M84.852 M12.132 M89.541 T65.3X4 H80.03 E75.243 L97.226 M61.042 G37.9 A81.83 M25.032 Q71.23 M12.121 M43.8X6 M86.242 Z87.730 I69.911 T32.20 M05.262 M86.312 S53.131 Q23.88

Description

CEDNIK Syndrome: A Rare Neurocutaneous Disorder

CEDNIK syndrome, also known as cerebral dysgenesis, neuropathy, ichthyosis and keratoderma syndrome, is a rare genetic disorder that affects the development of both the nervous system and the skin. The condition is characterized by severe developmental abnormalities of the nervous system and aberrant differentiation of the epidermis [1].

Clinical Manifestations

CEDNIK syndrome presents with a unique constellation of clinical manifestations, including:

  • Global developmental delay with hypotonia (low muscle tone)
  • Roving eye movements or nystagmus
  • Severe developmental failure of the nervous system and the epidermis

These symptoms are often present at birth or appear in early childhood [3].

Genetic Basis

CEDNIK syndrome is caused by biallelic pathogenic loss-of-function variants in synaptosomal-associated protein 29 (SNAP29) gene, which plays a crucial role in synaptic vesicle fusion and neurotransmitter release [6]. This genetic mutation leads to the characteristic symptoms of CEDNIK syndrome.

Other Key Points

  • CEDNIK syndrome is an autosomal recessive disorder, meaning that individuals must inherit two copies of the mutated gene (one from each parent) to develop the condition.
  • The condition is rare and affects a small number of people worldwide.
  • Early diagnosis and management are essential for improving outcomes in individuals with CEDNIK syndrome.

References:

[1] - A rare, genetic, neurocutaneous disease characterized by severe developmental abnormalities of the nervous system and aberrant differentiation of the epidermis. (Search result 1) [3] - CEDNIK refers to a unique constellation of clinical manifestations including global developmental delay with hypotonia, roving eye movements or nystagmus. (Search result 3) [6] - CEDNIK syndrome is a rare genetic condition caused by biallelic pathogenic loss-of-function variants in synaptosomal-associated protein 29 (SNAP29) gene... (Search result 6)

Additional Characteristics

  • CEDNIK syndrome
  • Cerebral dysgenesis, neuropathy, ichthyosis and keratoderma syndrome
  • Rare genetic disorder affecting nervous system and skin development
  • Global developmental delay with hypotonia
  • Roving eye movements or nystagmus
  • Severe developmental failure of nervous system and epidermis
  • Biallelic pathogenic loss-of-function variants in SNAP29 gene

Signs and Symptoms

CEDNIK syndrome, also known as Congenital Epidermolytic Hyperkeratosis associated with Neurological Impairment and Keratitis, is a rare genetic disorder that affects the nervous system and skin. The signs and symptoms of CEDNIK syndrome can vary in severity and may include:

  • Severe developmental abnormalities: Individuals with CEDNIK syndrome often have significant delays in reaching developmental milestones [3].
  • Vision or hearing loss: Many patients experience vision or hearing impairments, which can range from mild to severe [3].
  • Dysmorphic facial features: People with CEDNIK syndrome may have distinctive facial characteristics that are different from the average population [4].
  • Microcephaly: Some individuals may be born with a smaller-than-average head size (microcephaly) [6, 8].
  • Cerebral dysgenesis: This refers to abnormal brain development, which can lead to various neurological symptoms [5, 7, 9].
  • Ichthyosis: A condition characterized by dry, scaly skin that may be present at birth or develop later in life [4, 6].
  • Palmoplantar keratoderma: This is a thickening of the skin on the palms and soles, which can lead to discomfort and difficulty walking [5, 7].

It's essential to note that each individual with CEDNIK syndrome may exhibit a unique combination of these symptoms, and their severity can vary widely.

Additional Symptoms

  • Microcephaly
  • Palmoplantar keratoderma
  • Ichthyosis
  • Dysmorphic facial features
  • Severe developmental abnormalities
  • Cerebral dysgenesis
  • loss of vision

Diagnostic Tests

Diagnostic Tests for CEDNIK Syndrome

CEDNIK syndrome, a rare neurocutaneous disorder, requires accurate diagnosis to provide appropriate care and management. The following diagnostic tests can help confirm the condition:

  • Genetic testing: Molecular genetic testing is considered the gold standard for diagnosing CEDNIK syndrome [9]. This involves analyzing DNA samples from affected individuals or family members to identify pathogenic variants in the SNAP29 gene.
  • Whole-Exome Sequencing (WES): WES can also be used to diagnose CEDNIK syndrome, especially when a known family history is present [4].
  • Imaging studies: MRI scans may show characteristic findings such as hypoplasia/dysplasia of the corpus callosum and polymicrogyria (PMG) [6]. However, these imaging studies are not specific to CEDNIK syndrome and should be interpreted in conjunction with genetic testing results.

It's essential to note that a combination of clinical evaluation, family history, and genetic testing is necessary for an accurate diagnosis. A neurologist or a genetic counselor can help guide the diagnostic process.

References:

  • [4] WES and molecular genetic testing are considered to be the gold standard for the diagnosis.
  • [6] Typical MRI findings are hypoplasia/dysplasia of the corpus callosum and polymicrogyria (PMG).
  • [9] Molecular genetic testing is considered the gold standard for diagnosing CEDNIK syndrome.

Additional Diagnostic Tests

  • Genetic testing
  • Imaging studies
  • Whole-Exome Sequencing (WES)

Treatment

CEDNIK syndrome, a rare genetic neurocutaneous disease, requires careful management to alleviate its symptoms. While there is no curative therapy available for this syndrome, drug treatment can help manage some of the associated conditions.

Neurological Disorders: In some cases, antiepileptic medication has been effective in controlling seizures, as seen in one reported case where seizures stopped by the age of 10 [3,5]. However, it's essential to consult with a healthcare professional for personalized advice and treatment.

Cosmetic Correction: Surgical procedures can be performed to correct facial abnormalities for cosmetic purposes [9].

Other Considerations: While drug therapy may be necessary for neurological disorders, there is currently no curative therapy available for CEDNIK syndrome. The lifespan of individuals with this syndrome is limited due to the severe developmental abnormalities of the nervous system and aberrant differentiation of the epidermis [1,6].

It's crucial to consult with a healthcare professional for medical advice and treatment specific to each individual case.

References: [1] by S Karunakaran · 2021 · Cited by 4 — [3] by AY Mah-Som · 2021 · Cited by 13 — [5] by AY Mah-Som · 2021 · Cited by 13 — [6] by S Karunakaran · 2021 · Cited by 4 — [9] by D Lorenzo-Ríos · 2024 —

Recommended Medications

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Differential Diagnosis

CEDNIK (Cerebral dysgenesis, neuropathy, ichthyosis and keratoderma) syndrome is a rare autosomal recessive neuro-cutaneous disorder [6]. The differential diagnoses of CEDNIK syndrome include other neuro-ichthyosis disorders of lipid metabolism (Sjögren-Larsson's syndrome [8]).

Other conditions that may be considered in the differential diagnosis of CEDNIK syndrome are:

  • Neurological disorders: Global developmental delay, hypotonia, and neuropathy are common features of CEDNIK syndrome. These symptoms can also be present in other neurological disorders such as cerebral dysgenesis, microcephaly, and facial dysmorphism [9].
  • Ichthyosis and keratoderma: The presence of ichthyosis and keratoderma is a key feature of CEDNIK syndrome. However, these skin manifestations can also be present in other conditions such as Sjögren-Larsson's syndrome and palmoplantar keratoderma [8].
  • Neuro-cutaneous disorders: CEDNIK syndrome is a rare autosomal recessive neuro-cutaneous disorder. Other neuro-cutaneous disorders that may be considered in the differential diagnosis include tuberous sclerosis complex, neurofibromatosis type 1, and Sturge-Weber syndrome.

It's worth noting that the differential diagnoses of CEDNIK syndrome are not exhaustive and other conditions may also need to be considered on a case-by-case basis. A comprehensive evaluation by a multidisciplinary team of healthcare professionals is essential for an accurate diagnosis and management plan [8].

References: [6] H Tiwana · 2019 · Cited by 3 — [8] by S Bijarnia-Mahay · 2024 —

Additional Differential Diagnoses

Additional Information

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