Discuss This Drug

mercaptopurine

CHEBI:CHEBI_50667

Definition

A member of the class of purines that is 6,7-dihydro-1H-purine carrying a thione group at position 6. An adenine analogue, it is used in the treatment of acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn's disease, and ulcerative colitis.

Chemical Information

Molecular Formula
C5H4N4S
Molecular Mass
152.17822
Charge
0
SMILES
S=c1[nH]cnc2nc[nH]c12
InChI
InChI=1S/C5H4N4S/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10)
InChIKey
GLVAUDGFNGKCSF-UHFFFAOYSA-N

Alternative Names

  • 6-MP
  • 6-Thiohypoxanthine
  • 1,7-dihydro-6H-purine-6-thione
  • 6 MP
  • 6-Mercaptopurine
  • 6-Thioxopurine
  • Mercaptopurina
  • mercaptopurine
  • mercaptopurine
  • Mercaptopurine
  • mercaptopurinum
  • Mercapurin
  • Puri-Nethol
  • Purinethol

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:50667
oboInOwl#hasDbXref
Reaxys:132916
DRON_00010000
103

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:50667
rxcui
197931
active_ingredient_strength
1 kg/kg
manufacturer_name
Hikma Pharmaceuticals USA Inc.
package_marketing_start_date
15-JAN-01
active_ingredient_name
MERCAPTOPURINE
unii
E7WED276I5
spl_set_id
c3b5b8b0-bc5c-4ce9-bbdc-febba60c2658
upc
0300544581110
pharm_class
Nucleoside Metabolic Inhibitor [EPC]
package_description
25 kg in 1 DRUM (66122-0016-8)
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Reaxys:132916
DRON_00010000
103
oboInOwl#id
CHEBI:50667
generic_name
MERCAPTOPURINE MONOHYDRATE
brand_name
Mercaptopurine
brand_name_base
Mercaptopurine
product_type
BULK INGREDIENT
listing_expiration_date
20241231
route
ORAL
dosage_form
POWDER
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
product_ndc
15308-0712
application_number
ANDA040528
labeler_name
Zhejiang Cheng Yi Pharmaceutical Co., Ltd
marketing_start_date
20010115
spl_id
aa49d152-d6bf-4a05-b9d3-835b8b2e32f5
package_ndc
15308-0712-0
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35610
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_tautomer_of
http://purl.obolibrary.org/obo/CHEBI_2208
has_treatment
http://purl.obolibrary.org/obo/DOID_11606
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113315
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect13558
owl#someValuesFrom
t3005030
owl#annotatedSource
t238770