Nitrazepam
CHEBI:CHEBI_7581
Definition
A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one which is substituted at positions 5 and 7 by phenyl and nitro groups, respectively. It is used as a hypnotic for the short-term management of insomnia and for the treatment of epileptic spasms in infants (West's syndrome).
Chemical Information
- Molecular Formula
- C15H11N3O3
- Molecular Mass
- 281.26610
- Charge
- 0
- SMILES
- [O-][N+](=O)c1ccc2NC(=O)CN=C(c3ccccc3)c2c1
- InChI
- InChI=1S/C15H11N3O3/c19-14-9-16-15(10-4-2-1-3-5-10)12-8-11(18(20)21)6-7-13(12)17-14/h1-8H,9H2,(H,17,19)
- InChIKey
- KJONHKAYOJNZEC-UHFFFAOYSA-N
Alternative Names
- Dormicum
- 1,3-dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepin-2-one
- 2,3-dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-one
- 7-nitro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one
- 7-nitro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
- 7-nitro-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
- Apodorm
- Atempol
- Benzalin
- Calsmin
- Eatan
- Eunoctin
- Gerson
- Hipnax
- Hipsal
- Ibrovek
- Imeson
- Imesont
- Mogadon
- N-desmethylnimetazepam
- Nelbon
- Nelmat
- Neozepam
- Neuchlonic
- Nitrados
- nitrazepam
- nitrazepamum
- Paxisyn
- Pelson
- Persopit
- Radedorm
- Relact
- Remnos
- Ro 4-5360
- Ro 5-3059
- Somitran
- Sonebon
- Sonnolin
- Surem
- Trazenin
- Unisomnia
Treatment Applications
-
Lennox-Gastaut syndromeView Disease →
DOID:0050561
-
West syndromeView Disease →
DOID:0050562
-
electroclinical syndromeView Disease →
DOID:0050701
-
neonatal period electroclinical syndromeView Disease →
DOID:0050702
-
infancy electroclinical syndromeView Disease →
DOID:0050703
-
childhood electroclinical syndromeView Disease →
DOID:0050704
-
early infantile epileptic encephalopathyView Disease →
DOID:0050709
-
Qazi Markouizos syndromeView Disease →
DOID:0050740
-
juvenile absence epilepsyView Disease →
DOID:0060172
-
pontocerebellar hypoplasia type 2BView Disease →
DOID:0060268
-
pontocerebellar hypoplasia type 2CView Disease →
DOID:0060269
-
pontocerebellar hypoplasia type 10View Disease →
DOID:0060279
-
NFIA-related disorderView Disease →
DOID:0060409
-
Pitt-Hopkins syndromeView Disease →
DOID:0060488
-
Compton-North congenital myopathyView Disease →
DOID:0080101
-
hot water epilepsy 1View Disease →
DOID:0081106
-
hot water epilepsy 2View Disease →
DOID:0081107
-
congenital myopathy 15View Disease →
DOID:0081347
-
developmental and epileptic encephalopathyView Disease →
DOID:0112202
-
benign neonatal seizuresView Disease →
DOID:14264
-
benign familial neonatal epilepsyView Disease →
DOID:14777
-
Landau-Kleffner syndromeView Disease →
DOID:2538
Drug Classification
-
1,4-benzodiazepinoneView Class →
CHEBI:35500
-
C-nitro compoundView Class →
CHEBI:35716
-
t285718
-
t286320
-
t286723
-
t286965
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Nitrazepam
- DRON_00010000
- 7440
- core#notation
- CHEBI:7581
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Nitrazepam
- DRON_00010000
- 7440
- oboInOwl#id
- CHEBI:7581
- core#notation
- CHEBI:7581
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_49103
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_109813
- owl#annotatedSource
- t287133
- owl#someValuesFrom
- t783871