flubendazole
CHEBI:CHEBI_77095
Definition
A member of the class of mebendazole in which the benzoyl group is replaced by a p-fluorobenzoyl group. A broad-spectrum anthelmintic, it is used, particularly in veterinary medicine, for the treatment of nematodal infections.
Chemical Information
- Molecular Formula
- C16H12FN3O3
- Molecular Mass
- 313.28320
- Charge
- 0
- SMILES
- COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c1ccc(F)cc1
- InChI
- InChI=1S/C16H12FN3O3/c1-23-16(22)20-15-18-12-7-4-10(8-13(12)19-15)14(21)9-2-5-11(17)6-3-9/h2-8H,1H3,(H2,18,19,20,22)
- InChIKey
- CPEUVMUXAHMANV-UHFFFAOYSA-N
Alternative Names
- (5-(4-fluorobenzoyl)-1H-benzimidazole-2-yl)carbamic acid methyl ester
- flubendazol
- flubendazole
- flubendazolum
- methyl [5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate
- methyl 5-(p-fluorobenzoyl)-2-benzimidazolecarbamate
- Methyl N-(5-(p-fluorobenzoyl)-2-benzimidazolyl)carbamate
- R 17,889
- R 17899
Treatment Applications
-
obsolete Brugia timori filariasisView Disease →
DOID:0050249
-
parasitic Ichthyosporea infectious diseaseView Disease →
DOID:0050291
-
filariasisView Disease →
DOID:1080
-
dirofilariasisView Disease →
DOID:1082
-
strongyloidiasisView Disease →
DOID:10955
-
obsolete Brugia malayi filariasisView Disease →
DOID:14421
-
ostertagiasisView Disease →
DOID:3985
-
fasciolopsiasisView Disease →
DOID:888
Drug Classification
-
carbamate esterView Class →
CHEBI:23003
-
organofluorine compoundView Class →
CHEBI:37143
-
aromatic ketoneView Class →
CHEBI:76224
-
benzimidazolesView Class →
CHEBI:22715
-
t293164
-
t293505
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Flubendazole
- DRON_00010000
- 25096
- core#notation
- CHEBI:77095
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Flubendazole
- DRON_00010000
- 25096
- oboInOwl#id
- CHEBI:77095
- core#notation
- CHEBI:77095
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_35444
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_113428
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect34726
- owl#annotatedSource
- t293822
- owl#someValuesFrom
- t778527