propamidine
CHEBI:CHEBI_87462
Definition
A polyether that is the bis(4-guanidinophenyl) ether of propane-1,3-diol. Used (as its isethionate salt) for the treatment of minor eye or eyelid infections, such as conjunctivitis and blepharitis.
Chemical Information
- Molecular Formula
- C17H20N4O2
- Molecular Mass
- 312.36630
- Charge
- 0
- SMILES
- NC(=N)c1ccc(OCCCOc2ccc(cc2)C(N)=N)cc1
- InChI
- InChI=1S/C17H20N4O2/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21/h2-9H,1,10-11H2,(H3,18,19)(H3,20,21)
- InChIKey
- WTFXJFJYEJZMFO-UHFFFAOYSA-N
Alternative Names
- 4,4'-(1,3-Propanediylbis(oxy))bis-benzenecarboximidamide
- 4,4'-(Trimethylenedioxy)dibenzamidine
- 4,4'-[propane-1,3-diylbis(oxy)]di(benzene-1-carboximidamide)
- propamidina
- propamidine
- propamidinum
Treatment Applications
-
philophthalmiasisView Disease →
DOID:0050250
-
pseudomembranous conjunctivitisView Disease →
DOID:11190
-
Angelucci's syndromeView Disease →
DOID:11203
-
acute hemorrhagic conjunctivitisView Disease →
DOID:11227
-
trachomaView Disease →
DOID:11265
-
Mikulicz diseaseView Disease →
DOID:12900
-
oculoglandular tularemiaView Disease →
DOID:13226
-
parasitic conjunctivitisView Disease →
DOID:13341
-
inclusion conjunctivitisView Disease →
DOID:13800
-
squamous blepharitisView Disease →
DOID:13825
-
contact blepharoconjunctivitisView Disease →
DOID:13999
-
blepharoconjunctivitisView Disease →
DOID:2456
-
blepharitisView Disease →
DOID:9423
-
angular blepharoconjunctivitisView Disease →
DOID:2455
-
papillary conjunctivitisView Disease →
DOID:2458
-
vernal conjunctivitisView Disease →
DOID:2474
-
obsolete rinderpestView Disease →
DOID:4104
-
Ebola hemorrhagic feverView Disease →
DOID:4325
-
acute canaliculitisView Disease →
DOID:6969
-
ulcerative blepharitisView Disease →
DOID:9483
-
bacterial conjunctivitisView Disease →
DOID:9700
-
meibomian cystView Disease →
DOID:9903
Drug Classification
-
aromatic etherView Class →
CHEBI:35618
-
guanidinesView Class →
CHEBI:24436
-
polyetherView Class →
CHEBI:46774
-
t313256
-
t313805
-
t313836
-
t314196
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 34633
- oboInOwl#hasDbXref
- Wikipedia:Propamidine
- core#notation
- CHEBI:87462
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 34633
- oboInOwl#hasDbXref
- Wikipedia:Propamidine
- oboInOwl#id
- CHEBI:87462
- core#notation
- CHEBI:87462
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_48218
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_16109
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_87463
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_113868
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect37576
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_87463
- owl#annotatedSource
- t314327
- owl#someValuesFrom
- t566854