Tolonium chloride
CHEBI:CHEBI_87647
Definition
An organic chloride salt having 3-amino-7-(dimethylamino)-2-methylphenothiazin-5-ium (tolonium) as the counterion. It is a blue nuclear counterstain that can be used to demonstrate Nissl substance and is also useful for staining mast cell granules, both in metachromatic and orthochromatic techniques.
Chemical Information
- Molecular Formula
- C15H16ClN3S
- Molecular Mass
- 305.82600
- Charge
- 0
- SMILES
- [Cl-].CN(C)c1ccc2nc3cc(C)c(N)cc3[s+]c2c1
- InChI
- InChI=1S/C15H16N3S.ClH/c1-9-6-13-15(8-11(9)16)19-14-7-10(18(2)3)4-5-12(14)17-13;/h4-8H,16H2,1-3H3;1H/q+1;/p-1
- InChIKey
- HNONEKILPDHFOL-UHFFFAOYSA-M
Alternative Names
- 3-Amino-7-(dimethylamino)-2-(methylphenazathionium) chloride
- 3-amino-7-(dimethylamino)-2-methylphenothiazin-5-ium chloride
- basic blue 17
- Blutene chloride
- C.I. 52040
- C.I. 925
- C.I. Basic Blue 17
- chlorure de tolonium
- cloruro de tolonio
- Dimethyltoluthionine chloride
- toloni chloridum
- tolonii chloridum
- tolonium chloride
- Toluidene Blue O Chloride
- Toluidinblau
- toluidine blue
- toluidine blue O
Treatment Applications
-
mast-cell leukemiaView Disease →
DOID:9254
Drug Classification
-
organic chloride saltView Class →
CHEBI:36094
-
t313359
-
t313949
-
t314132
-
t314266
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 10638
- oboInOwl#hasDbXref
- Wikipedia:Tolonium_chloride
- core#notation
- CHEBI:87647
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 10638
- oboInOwl#hasDbXref
- Wikipedia:Tolonium_chloride
- oboInOwl#id
- CHEBI:87647
- core#notation
- CHEBI:87647
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_51217
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- BFO_0000051
- http://purl.obolibrary.org/obo/CHEBI_87648
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_113610
- owl#annotatedSource
- t314340
- owl#someValuesFrom
- t568934