sodium aurothiomalate allergy

Sodium Aurothiomalate Allergy: Symptoms and Reactions

A sodium aurothiomalate allergy can manifest in various ways, ranging from mild to severe reactions. Some common symptoms include:

• Skin rash: A severe or blistering skin rash is a possible sign of an allergic reaction to sodium aurothiomalate [6].
• Respiratory issues: Feeling breathless, dry cough, and chest pain can be indicative of an allergic response [6].
• Gastrointestinal problems: Stomach pains and loose, watery stools may also occur as a result of the allergy [6].

In rare cases, anaphylactoid reactions have been reported, characterized by: * Dizziness * Nausea * Vomiting * Sweating * Facial flushing

These symptoms can be severe and require immediate medical attention.

Important Note: If you experience any of these symptoms after taking sodium aurothiomalate or suspect an allergic reaction, seek medical help immediately.

Based on the provided context, it appears that an allergic reaction to sodium aurothiomalate can manifest in various ways.

Common signs and symptoms include:

• Skin reactions such as rash, pruritus (itching), urticaria (hives)
• Stomatitis (inflammation of the mouth) with shallow ulcers on the buccal membranes, tongue, palate, or pharynx
• Dermatitis (skin inflammation)
• Proteinuria (excess protein in urine)

Other possible symptoms may include:

• Pulmonary symptoms such as tightness in the throat and chest, wheezing, cough, and dyspnea (shortness of breath)
• Numbness, paresthesias (abnormal sensations), and distal weakness
• Myokymia (unusual muscle twitching)

Severe reactions may also occur:

• Severe or bloody diarrhea
• Easy bruising or bleeding
• Confusion, hallucinations, or seizure

It is essential to report any side effects to the specialist or GP while receiving sodium aurothiomalate and to provide monitoring booklet updates. If symptoms of systemic infection develop, treatment should be initiated promptly, and sodium aurothiomalate withheld until the infection has cleared.

References:

• [1] Skin reactions such as rash, pruritus (itching), urticaria (hives) - 6
• [2] Stomatitis (inflammation of the mouth) with shallow ulcers on the buccal membranes, tongue, palate, or pharynx - 5
• [3] Dermatitis (skin inflammation) - 6
• [4] Proteinuria (excess protein in urine) - 6
• [5] Pulmonary symptoms such as tightness in the throat and chest, wheezing, cough, and dyspnea (shortness of breath) - 3
• [6] Numbness, paresthesias (abnormal sensations), and distal weakness - 2
• [7] Myokymia (unusual muscle twitching) - 2
• [8] Severe reactions may also occur: severe or bloody diarrhea - 4
• [9] Easy bruising or bleeding - 4
• [10] Confusion, hallucinations, or seizure - 11

Based on the provided context, it appears that diagnostic tests for sodium aurothiomalate allergy are not explicitly mentioned. However, I can provide information on general diagnostic tests related to allergies.

Diagnostic Tests for Allergies

Allergy skin tests (immediate hypersensitivity testing) are an in vivo method of determining immediate (IgE-mediated) hypersensitivity to specific allergens [14]. These tests involve introducing a small amount of the suspected allergen into the skin, and observing the reaction. This can help determine sensitivity to virtually all of the allergens that cause allergic rhinitis.

Other Diagnostic Tests

In addition to allergy skin tests, other diagnostic tests may be used to diagnose allergies, such as:

• Blood tests (e.g., RAST or ELISA) to measure IgE antibodies against specific allergens
• In vitro tests, such as basophil activation tests, to assess cell-mediated immune responses

However, it's essential to note that these tests are not specifically mentioned in the context provided. If you're looking for information on diagnostic tests for sodium aurothiomalate allergy, I couldn't find any relevant information in the search results.

If you'd like me to search again or provide more general information on allergies and their diagnosis, please let me know!

Alternative Treatments for Sodium Aurothiomalate Allergy

If you are allergic to sodium aurothiomalate, it's essential to explore alternative treatments that can manage your symptoms without exacerbating the allergy. Here are some options:

• Methotrexate: As mentioned in context 8, methotrexate replaced gold injections as the first-line treatment for rheumatoid arthritis (RA) in 1985. This medication can be considered as an alternative to sodium aurothiomalate.
• Other DMARDs: Disease-modifying antirheumatic drugs (DMARDs) like sulfasalazine, hydroxychloroquine, and leflunomide may be used to treat RA symptoms while avoiding gold-based medications 1.
• Biologics: Biologic agents such as tumor necrosis factor-alpha inhibitors (TNF-α inhibitors), interleukin-6 receptor inhibitors, and Janus kinase inhibitors can also be effective in managing RA symptoms 2.

Important Considerations

Before switching to an alternative treatment, consult with your healthcare provider to discuss the potential risks and benefits. They will help determine the best course of action based on your individual needs and medical history.

References

[1] Context 4: If there is no response after a cumulative dose of 1000mg has

Understanding Sodium Aurothiomalate Allergy

Sodium aurothiomalate, also known as gold salt or Myocrisin, is a medication used to treat rheumatoid arthritis and other inflammatory conditions. However, like any medication, it can cause allergic reactions in some individuals.

Differential Diagnosis of Sodium Aurothiomalate Allergy

When diagnosing an allergy to sodium aurothiomalate, healthcare professionals must consider various factors to rule out other possible causes of the reaction. According to medical research [3][7], the differential diagnosis for sodium aurothiomalate allergy includes:

• Skin reactions: Many adverse reactions allegedly due to chrysotherapy (treatment with gold salts) may have other causes, particularly in the case of skin reactions [1][2].
• Contact dermatitis: This is a type of skin reaction that can be caused by various factors, including medications like sodium aurothiomalate.
• Nickel contamination: Some research suggests that nickel contaminating the gold salt may cause allergic reactions [7].

Symptoms to Consider

When diagnosing an allergy to sodium aurothiomalate, healthcare professionals should consider symptoms such as:

• Severe or blistering skin rash
• Signs of an allergic reaction (e.g., hives, itching)
• Feeling breathless, dry cough, chest pain [5]

Treatment and Management

If an individual is diagnosed with a sodium aurothiomalate allergy, healthcare professionals may recommend alternative treatments for their condition. In some cases, the treatment may need to be stopped altogether.

References:

[1] Å Svensson · 2002 · Cited by 22 — Contact allergy to gold, as diagnosed by patch testing with gold sodium thiosulfate (GSTS), is very common among patients with eczematous disease [1-3].

[2] It should always be borne in mind that many adverse reactions allegedly due to chrysotherapy may have other causes, particularly in the case of skin reactions.

[3] by Å Svensson · 2002 · Cited by 22 — Contact allergy to gold, as diagnosed by patch testing with gold sodium thiosulfate (GSTS), is very common among patients with eczematous disease [1-3].

[5] Can sodium aurothiomalate cause problems? · A severe or blistering skin rash, or any signs of an allergic reaction. · Feeling breathless, dry cough, chest pain.

[7] by EH Choy · 1997 · Cited by 9 — The pathogenic mechanisms of these are unknown, but could include allergic reactions to gold or to nickel contaminating the gold.