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medulloblastoma
ICD-10 Codes
Description
Medulloblastoma: A Rare and Aggressive Brain Tumor
Medulloblastoma is a type of cancerous brain tumor that affects the central nervous system (CNS). It begins in the cerebellum, which is the part of the brain responsible for muscle coordination and balance. The tumor grows quickly and can spread to other areas of the brain.
Characteristics of Medulloblastoma
- Fast-growing: Medulloblastomas are known to grow rapidly, making them a serious concern.
- Cancerous: This type of tumor is malignant, meaning it has the potential to invade surrounding tissues and spread to other parts of the body.
- Rare in adults: While medulloblastoma can occur at any age, it is most commonly diagnosed in children.
Symptoms and Effects
The symptoms of medulloblastoma can vary depending on the location and size of the tumor. Some common effects include:
- Increased intracranial pressure
- Cerebellar dysfunction (e.g., coordination problems)
- Emotional lability (mood swings)
- Axial hypotonia (weakness in the muscles)
Prevalence and Statistics
Medulloblastoma is the most common malignant pediatric tumor in the central nervous system, accounting for nearly 20% of all childhood brain cancers.
References:
- [1] Medulloblastoma begins as a growth of cells, which is called a tumor. The cells grow quickly and can spread to other parts of the brain. (Source: #1)
- [2] Medulloblastoma is a primary central nervous system (CNS) tumor. This means it begins in the brain or spinal cord. (Source: #2)
- [3] Medulloblastoma is a cancerous brain tumor that starts near your brainstem, in your cerebellum. The tumor is fast growing and can spread to other areas of your ... (Source: #3)
- [4] Medulloblastoma is the most common malignant pediatric tumor in the central nervous system (CNS), accounting for nearly 20% of all childhood brain cancers. (Source: #4)
Additional Characteristics
- Increased intracranial pressure
- Medulloblastoma is a type of cancerous brain tumor that affects the central nervous system (CNS).
- It begins in the cerebellum, which is the part of the brain responsible for muscle coordination and balance.
- The tumor grows quickly and can spread to other areas of the brain.
- Medulloblastomas are known to grow rapidly, making them a serious concern.
- This type of tumor is malignant, meaning it has the potential to invade surrounding tissues and spread to other parts of the body.
- Medulloblastoma can occur at any age, but it is most commonly diagnosed in children.
- The symptoms of medulloblastoma can vary depending on the location and size of the tumor.
- Cerebellar dysfunction (e.g., coordination problems)
- Emotional lability (mood swings)
- Axial hypotonia (weakness in the muscles)
- Medulloblastoma is the most common malignant pediatric tumor in the central nervous system, accounting for nearly 20% of all childhood brain cancers.
Signs and Symptoms
Common Signs and Symptoms of Medulloblastoma
Medulloblastoma, a type of brain cancer that primarily affects children, can exhibit various signs and symptoms. These may include:
- Headaches: A frequent symptom, often worse in the morning [1][2][3][4]
- Nausea and vomiting: May occur alone or accompanied by headaches [1][2][5][7]
- Fatigue and lethargy: Patients may feel extremely tired or weak [5]
- Balance problems and difficulty walking: Clumsiness, stumbling, or tilting the head to one side can be indicative of medulloblastoma [6][9]
- Vision changes: Blurred or double vision may occur due to the tumor's impact on the brain [2][3]
- Coordination difficulties: Poor coordination and muscle tone issues can also be symptoms [8]
It is essential to note that these signs and symptoms can vary in severity and may not always be present. If you suspect someone has medulloblastoma, it is crucial to consult a medical professional for proper diagnosis and treatment.
References: [1] - Context result 1 [2] - Context result 2 [3] - Context result 3 [4] - Context result 4 [5] - Context result 5 [6] - Context result 6 [7] - Context result 7 [8] - Context result 8 [9] - Context result 9
Additional Symptoms
- Nausea and vomiting
- Vision changes
- Headaches
- Fatigue and lethargy
- Balance problems and difficulty walking
- Coordination difficulties
Diagnostic Tests
Diagnostic Tests for Medulloblastoma
Medulloblastoma, a type of brain cancer, requires prompt and accurate diagnosis to determine the best course of treatment. The following diagnostic tests are commonly used to diagnose medulloblastoma:
- Magnetic Resonance Imaging (MRI): An MRI scan with gadolinium DTPA is the diagnostic test of choice for medulloblastoma [2]. This imaging technique
Additional Diagnostic Tests
- Magnetic Resonance Imaging (MRI)
Treatment
Medulloblastoma, a
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Differential Diagnosis
Medulloblastoma Differential Diagnosis
Medulloblastoma, a type of brain tumor, requires accurate differential diagnosis to ensure proper treatment and prognosis. The following conditions are often considered in the differential diagnosis of medulloblastoma:
- Ependymoma: A tumor that usually arises from the floor of the 4th ventricle and typically squeezes out the foramen of Luschka [3].
- Atypical teratoid/rhabdoid tumor (AT/RT): A rare and aggressive brain tumor that can be mistaken for medulloblastoma due to similar symptoms [4].
- Cerebellar pilocytic astrocytoma: A type of brain tumor that can present with similar symptoms as medulloblastoma, including cerebellar signs and symptoms [4].
- Choroid plexus carcinoma: A rare brain tumor that can be mistaken for medulloblastoma due to its location in the cerebellum [4].
- Dorsally located tumors: Such as ependymomas or glioblastomas, which can present with similar symptoms as medulloblastoma [4].
Key Considerations
When differentiating medulloblastoma from other brain tumors, it is essential to consider the following factors:
- Age at diagnosis: Medulloblastoma typically affects children and young adults, while other brain tumors may have a broader age range [2].
- Presence of metastases: The presence of metastases can indicate a more aggressive tumor type, such as medulloblastoma [2].
- Subgroup variant of medulloblastoma: Certain subgroups of medulloblastoma, such as the WNT subgroup, may have distinct characteristics that aid in differential diagnosis [2].
References
[1] Sep 27, 2022 — Differential Diagnoses · Brainstem Gliomas · Cavernous Sinus Syndromes · Cerebellar Hemorrhage · Cerebral Aneurysms · Glioblastoma. [2] by S Mahapatra · 2023 · Cited by 27 — This wide range is multifactorial, owing in part to age at diagnosis, presence of metastases at diagnosis, subgroup variant of medulloblastoma, and concurrent ... [3] Oct 14, 2024 — Differential diagnosis ; ependymoma. usually arises from the floor of the 4th ventricle. typically squeezes out the foramen of Luschka. does not ... [4] Sep 27, 2022 — Differential Diagnoses · Brainstem Gliomas · Cavernous Sinus Syndromes · Cerebellar Hemorrhage · Cerebral Aneurysms · Glioblastoma.
Additional Differential Diagnoses
- choroid plexus carcinoma
- Ependymoma
- RT)
- Cerebellar pilocytic astrocytoma
- Dorsally located tumors
- central nervous system embryonal tumor
- medulloblastoma SHH activated
- medulloblastoma non-WNT/non-SHH group 4
- diffuse glioma, H3 G34 mutant
- posterior fossa ependymoma
- supratentorial ependymoma
- embryonal tumor with multilayered rosettes, C19MC-altered
- posterior fossa group B ependymoma
- embryonal tumor with multilayered rosettes
- neuroectodermal tumor
- atypical teratoid rhabdoid tumor
- obsolete medulloblastoma with leptomeningeal spread
- childhood infratentorial neoplasm
- intracranial primitive neuroectodermal tumor
- cerebellar astrocytoma
- central nervous system melanocytic neoplasm
- childhood cerebellar neoplasm
- obsolete central nervous system soft tissue neoplasm
- obsolete recurrent pediatric cerebellar astrocytoma
- obsolete recurrent childhood central nervous system tumor
- obsolete pediatric CNS teratoma
Additional Information
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