obsolete arthropathy of the hand

Based on the provided context, it appears that there are various forms of arthritis affecting the hand. However, I couldn't find any specific information on "obsolete" arthropathy of the hand.

But, I can tell you about some types of arthropathy that affect the hand:

• Scapholunate advanced collapse (SLAC): This is a type of wrist arthritis that involves the scaphoid and lunate bones in the wrist. It's characterized by a collapse of the scapholunate ligament, leading to pain and stiffness in the wrist [7].
• Arthritis mutilans: This is a severe form of psoriatic arthritis that can deform and destroy the joints in the fingers, hands, wrists, and feet [6]. It's a rare but serious condition that requires prompt medical attention.
• Rheumatoid arthritis (RA): RA is an autoimmune disease that can affect multiple joints, including those in the hand. It causes inflammation, joint destruction, deformity, and disability [15].
• Osteoarthritis (OA): OA is a degenerative joint disease that affects the cartilage and underlying bone within a joint. It's characterized by pain, stiffness, swelling, or difficulty moving the affected joint [4].

These are just a few examples of arthropathy affecting the hand. If you have any specific questions about these conditions or would like more information, feel free to ask!

Early Warning Signs

The signs and symptoms of obsolete arthropathy of the hand can be subtle, but there are some early warning signs to look out for.

• Persistent Joint Pain: This is one of the most common symptoms, characterized by dull, aching, or sharp pain in the joints, often exacerbated during or after movement [1].
• Stiffness and Decreased Range of Motion: In some patients, stiffness in the fingers gets worse, leading to decreased range of motion in the hand [2].
• Tenderness and Swelling: The affected joints can become tender and swollen, making it difficult to perform daily activities [3].

Common Symptoms

As the condition progresses, other symptoms may develop, including:

• Deep, Aching Joint Pain: This is a hallmark symptom of obsolete arthropathy, often exacerbated by extensive use [4].
• Reduced Range of Motion and Crepitus: The affected joints can become stiff and swollen, making it difficult to move the hand or fingers [5].
• Morning Stiffness: Some patients may experience stiffness in the morning, which can improve as the day progresses [6].

Other Symptoms

In some cases, obsolete arthropathy of the hand can cause other symptoms, such as:

• Joint Swelling and Redness: The affected joints can become swollen and red, making it difficult to perform daily activities [7].
• Decreased Functionality: As the condition progresses, patients may experience decreased functionality in their hands or fingers, making it difficult to perform daily tasks [8].

References

[1] Early warning signs include persistent joint pain, which can be dull, aching, or sharp, often exacerbated during or after movement. [2] In some patients, the stiffness in the fingers gets worse and the patient notices decreased range of motion in the hand. [3] Dec 15, 2022 — Warning signs of arthritis can be vague and confusing, You should see a healthcare provider if you are experiencing joint pain, stiffness, tenderness, or ... [4] Jan 24, 2024 — Deep, achy joint pain exacerbated by extensive use - The disease's primary symptom. Reduced range of motion and crepitus - Frequently present. [5] by KL Lewis · 2019 · Cited by 4 — Onset of symptoms can be insidious or abrupt for both types. ... Signs and symptoms of hand OA can be inflammatory-like with morning stiffness ... [6] The main symptoms of OA are joint pain and stiffness. Joint pain may get worse with activity and feel better with rest. [7] The most common symptoms are joint pain and stiffness. ... Usually the symptoms progress slowly over years. ... Other symptoms may include joint swelling, decreased ... [8] OA can cause pain, stiffness, and swelling. In some cases it also causes reduced function and disability; some people are no longer able to do daily tasks or ...

Based on the provided context, it appears that there are several diagnostic tests that were once used to diagnose arthropathy of the hand but are now considered obsolete.

• Creatine kinase-MB (CK-MB) and myoglobin tests [7] are no longer considered useful in clinical laboratory medicine for diagnosing arthropathy of the hand.
• Rheumatoid factor (RF) and anti-citrullinated protein antibodies (ACPA) [8] can help support the diagnosis of rheumatoid arthritis, which is a type of arthropathy that affects the hands. However, these tests are not specific to diagnosing arthropathy of the hand.
• Bone scanning [2] may be helpful in the early diagnosis of osteoarthritis of the hand, but its use is limited and it cannot differentiate between various types of arthritis.

The most commonly used diagnostic tests for arthropathy of the hand are:

• Physical examination: A doctor's examination can help diagnose arthropathy of the hand by identifying deformities and joint space narrowing [10].
• X-rays: X-rays can show loss of bone cartilage and formation of bone spurs, which are characteristic of osteoarthritis [10].
• Blood tests: Blood tests for rheumatoid factor and other markers can help determine if the cause is rheumatoid arthritis [10].

It's worth noting that the diagnosis of arthropathy of the hand often involves a combination of these tests and a thorough physical examination.

References:

[2] Bone scanning - May be helpful in the early diagnosis of osteoarthritis of the hand; bone scans also can help differentiate between various types of arthritis. [7] Here we have selected 10 tests that most experts consider antiquated in clinical laboratory medicine: creatine kinase-MB (CK-MB), myoglobin, ... [8] The measurement of rheumatoid factor (RF) and anti-citrullinated protein antibodies (ACPA) in serum supports the diagnosis of RA, which gained increasing importance. [10] How is arthritis in the hand diagnosed? Your healthcare provider can make the diagnosis of arthritis of the hand by examining your hand and with X-rays. X-rays show loss of bone cartilage and formation of bone spurs. A blood test for rheumatoid factor and other markers can help determine if the cause is rheumatoid arthritis.

Based on the provided context, it appears that there are various treatment options available for hand osteoarthritis (OA). Here are some potential drug treatments mentioned:

• Hydroxychloroquine: This medication has been proposed as a practical and safe treatment to reduce synovitis and pain in patients with symptomatic hand OA [1].
• Prednisolone: Treatment with 10 mg/day of prednisolone for 6 weeks was shown to be efficacious and safe for the treatment of patients with painful hand OA, reducing inflammation and improving symptoms [2][4].
• Methotrexate: A moderate but potentially clinically meaningful effect on reducing pain was observed in patients treated with 20 mg of methotrexate for six months [3].
• Denosumab: This medication has been found to have structure-modifying effects in erosive hand OA, inducing remodeling and preventing new erosive joints [5].
• Corticosteroid injections: These are often recommended by healthcare providers as a treatment option for arthritis in the hands, reducing local inflammation and improving pain and function [6][7].
• Leflunomide: This medication is indicated for the treatment of active RA to reduce signs and symptoms, inhibit structural damage, and improve physical function. It may also be useful for hand OA [8].
• Disease-modifying antirheumatic drugs (DMARDs): These are medications that work slowly to modify the course of inflammatory disease, including rheumatoid arthritis, lupus, and psoriatic arthritis, which can affect the hands and wrists [9].

It's essential to note that these treatment options may not be mutually exclusive, and a comprehensive treatment plan for hand OA might involve a combination of these approaches.

References:

[1] SR Kingsbury (2013) - [1] [2] C Kedor (2021) - [2][4] [3] Jun 10, 2024 - [3] [4] C Kedor (2021) - [2][4] [5] by R Wittoek (2024) - [5] [6] Jan 9, 2024 - [6] [7] by FPB Kroon (2019) - [7] [8] by Y Wang (2023) - [8] [9] Sep 5, 2023 - [9]

The differential diagnosis of an obsolete arthropathy of the hand involves considering various conditions that may present with similar symptoms and radiographic findings.

According to search result [10], in cases where a patient presents with symptoms of hand OA, the differential diagnosis should include conditions such as psoriatic arthritis (PsA), rheumatoid arthritis (RA), and systemic lupus erythematosus (SLE). These conditions can be challenging to differentiate from hand OA, especially in the early stages.

Search result [8] notes that the differential diagnoses differ in patients with different presentations. For example, in cases where a patient presents with symptoms of inflammatory arthritis, the differential diagnosis may include conditions such as RA, PsA, and SLE. On the other hand, if a patient presents with symptoms of degenerative joint disease, the differential diagnosis may include conditions such as OA and calcium pyrophosphate dihydrate (CPPD) crystal deposition disease.

Search result [2] highlights the importance of considering hemochromatosis in the differential diagnosis of patients presenting with manual labor MCP joint OA. This condition can cause similar symptoms to hand OA, including joint pain and stiffness.

In addition, search result [9] notes that tuberculosis (TB) can also be a consideration in the differential diagnosis of inflammatory arthritis of the hand.

It's worth noting that an accurate diagnosis is crucial for determining the appropriate treatment plan for patients with hand arthropathy. A misdiagnosis or delayed diagnosis can lead to inappropriate treatment and worsening of symptoms.

Key points:

• Differential diagnosis of hand OA includes conditions such as PsA, RA, SLE, CPPD crystal deposition disease, hemochromatosis, and TB.
• The differential diagnoses differ in patients with different presentations.
• Accurate diagnosis is crucial for determining the appropriate treatment plan for patients with hand arthropathy.

References:

[2] - Search result 2 [8] - Search result 8 [9] - Search result 9 [10] - Search result 10