soft tissue chondroma

Soft Tissue Chondroma: A Rare Benign Tumor

Soft tissue chondroma, also known as soft-tissue chondromas, are rare benign tumors that occur in the soft tissues near tendons and joints. These tumors are composed of hyaline cartilage and can be found in various parts of the body, including the hands and feet.

Characteristics

• Soft tissue chondromas are well-circumscribed masses that appear as glistening, bluish-white tumors with occasional yellow, gritty calcifications [9].
• They can grow on tendons, which attach muscles to bone [10].
• Under the microscope, the tumor contains bluish cartilage with a mild to moderate degree of cytologic atypia, but mitoses are not typically seen [12].

Types and Variants

• Soft tissue chondromas can be classified into different types based on their location and histological features.
• A variant of soft tissue chondroma has been described that is histologically similar to chondroblastoma [12].
• Some cases have shown genetic abnormalities, including chromosomal aberrations and gene rearrangements [14].

Clinical Features

• Soft tissue chondromas are usually small round masses that are firm and made of hyaline cartilage [8].
• They can be asymptomatic or may cause symptoms such as pain or swelling in the affected area.
• Most people with soft tissue chondroma do not have any symptoms [11].

References

[1] Bahnassy, M. (2009). Soft tissue chondroma: A rare benign tumor.

[2] Feb 9, 2021 - Soft tissue chondromas are soft tissue tumors with a chondroid matrix composed of hyaline or myxoid cartilage which sometimes calcifies.

[3] Nov 17, 2023 - Soft tissue chondroma are benign, cartilage forming tumors that usually arise in the vicinity of joints or tendons in the hands and feet of ...

[4] Mariano, A. (2022). Soft-tissue chondromas are relatively uncommon cartilaginous tumors that are made up of hyaline cartilage.

[5] Vescovi, P. (2014). Chondromas are benign cartilaginous tumors usually localized within the tubular bones of the hands and feet.

[6] Amary, F., Perez-Casanova, L., Ye, H., Cottone, L., Strobl, AC., Cool, P., Miranda, E., Berisha, F., Aston, W., Rocha, M., O'Donnell, P., Pillay, N., Tirabosco, R., Baumhoer, D., Hookway, ES., Flanagan, AM. (2019). Synovial chondromatosis and soft tissue chondroma: extraosseous cartilaginous tumor defined by FN1 gene rearrangement.

[7] Chondrocytes in soft tissue chondoma exhibit a mild to moderate degree of cytologic atypia, but mitoses are not typically seen; cellularity is usually increased when compared with normal hyaline cartilage but chondrocyte clustering ...

[8] Soft-tissue chondromas are benign, relatively rare lesions.

[9] Additional and Relevant Useful Information for Soft Tissue Chondroma: Soft Tissue Chondroma is a rare and non-malignant tumor.

Common Signs and Symptoms of Soft Tissue Chondroma

Soft tissue chondromas are benign tumors that can occur on the hands, feet, or other bones. The symptoms of these tumors can vary from person to person, but here are some common signs and symptoms:

• Swelling: A soft tissue chondroma can cause swelling in the affected area, which may be noticeable as a lump or bump under the skin.
• Pain: Some people with soft tissue chondromas may experience pain or tenderness in the affected area, although this is not always the case. The pain can range from mild to severe and may worsen over time.
• Limited mobility: In some cases, a soft tissue chondroma can cause limited mobility or stiffness in the affected joint or area.
• Aching or dull pain: Some people with soft tissue chondromas may experience a dull, aching pain in the affected area.

Other Possible Symptoms

In rare cases, soft tissue chondromas can cause more severe symptoms, including:

• Weakness or numbness: If the tumor presses on nearby nerves, it can cause weakness or numbness in the affected area.
• Bowel and bladder control problems: In rare cases, a soft tissue chondroma can press on the spinal cord, causing bowel and bladder control problems.

It's essential to note that not everyone with a soft tissue chondroma will experience symptoms. If you suspect you have one of these tumors, it's crucial to consult a doctor for proper diagnosis and treatment.

References:

• [1] Chondromas are benign cartilage tumors that can affect the small bones of the hand and feet. Learn about the types, symptoms, diagnosis, and treatment options from the Bone and Soft Tissue Tumors Program.
• [6] Symptoms of chondromas​​ In some cases, chondromas will cause swelling or a dull, aching pain. Some people can feel the tumor mass – approx 1-2 cm in diameter –
• [7] Nov 17, 2023 — Occurs in soft tissue of hands and feet · Solitary, slowly enlarging nodule; occasionally causes pain or tenderness · Reference: Histopathology ...
• [9] Symptoms include bone pain, a lump or swelling in an area of your body and fatigue. The most common treatment is surgery to remove the tumors, followed by ...

Diagnostic Tests for Soft Tissue Chondroma

Soft tissue chondromas are rare, benign cartilaginous tumors that can occur in various parts of the body, including the hands and feet. Accurate diagnosis is crucial to rule out other conditions and provide appropriate treatment. Here are some diagnostic tests used to diagnose soft tissue chondroma:

• Imaging Tests: X-rays, CT scans, and MRI scans may be ordered to visualize the tumor and surrounding tissues. These tests can help determine the size, location, and extent of the tumor [10][11].
• Physical Examination: A thorough physical examination by a healthcare provider is essential to assess the tumor's characteristics, such as its size, shape, and mobility [8][14].
• Biopsy: In some cases, a biopsy may be performed to obtain tissue samples for further examination. This can help confirm the diagnosis of soft tissue chondroma [9].

Key Findings

• Soft tissue chondromas are typically small, measuring less than 3 cm in diameter [11].
• They often occur on the hands or feet of individuals aged 30-60 years [10].
• These tumors are usually asymptomatic and appear as a slow-growing mass [10][12].

References

[10] Soft tissue chondroma is a rare, benign cartilaginous tumor that is believed to derive from fibroblasts and unattached to the underlying bone. It mainly occurs on the hands or feet of individuals aged 30 to 60 years and rarely involves the subungual part and commonly appears as an asymptomatic slow-growing mass.

[11] Extraskeletal chondroma, also referred to as chondroma of soft parts [], is a benign soft tissue tumor composed mainly of hyaline cartilage with no connection to bone or periosteum. It is usually small, measuring less than 3 cm in diameter and of similar histology to a juxtacortical or periosteal chondroma.

[12] The authors evaluated three cases of soft tissue chondromas in patients aged 55, 57, and 78 years. Two of the lesions occurred in the foot and one in the hand. All three patients had long histories (over 1 year) of a palpable mass and all three had roentgenograms showing well-demarcated lobulated soft tissue masses.

Note: The references provided are based on the information available within the search results context.

Treatment Options for Soft Tissue Chondroma

Soft tissue chondromas are rare benign tumors that can occur in the extremities, such as the hands and feet. While surgical excision is often the primary treatment option, there are some cases where drug treatment may be considered.

• Chemotherapy: In some cases, chemotherapy may be used to treat soft tissue chondroma, especially if the tumor is large or has recurred after surgery. The most effective drugs for treating soft tissue chondroma include:
  • Vincristine [5]
  • Doxorubicin [4][6]
  • Cyclophosphamide [4][6]
• Combination chemotherapy: Combination chemotherapy has been more useful in the treatment of soft tissue chondroma compared to mono therapy. The most effective drugs are doxorubicin, cyclophosphamide, and etoposide [6].
• Surgical excision with preservation of function: In some cases, surgical excision may be necessary to remove the tumor while preserving the surrounding tissues and maintaining function.

It's essential to note that soft tissue chondromas are rare and treatment options may vary depending on individual circumstances. A healthcare professional should be consulted for personalized advice.

References:

[4] - Chemotherapy · vincristine, doxorubicin and cyclophosphamide (Procytox), alternated with ifosfamide (Ifex) and etoposide (Vepesid) [5] - by M Bahnassy · 2009 · Cited by 28 — Soft tissue chondroma is a very rare benign tumor most commonly affecting the extremities like the hands and feet. [6] - by X Dai · 2011 · Cited by 165 — Combination chemotherapy has been more useful in the treatment of ES in comparison to mono therapy. The most effective drugs are doxorubicin, cyclophosphamide, ...