Aminolevulinic Acid
CHEBI:CHEBI_17549
Definition
The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
Chemical Information
- Molecular Formula
- C5H9NO3
- Molecular Mass
- 131.12990
- Charge
- 0
- SMILES
- NCC(=O)CCC(O)=O
- InChI
- InChI=1S/C5H9NO3/c6-3-4(7)1-2-5(8)9/h1-3,6H2,(H,8,9)
- InChIKey
- ZGXJTSGNIOSYLO-UHFFFAOYSA-N
Alternative Names
- 5-ALA
- 5-Amino-4-oxopentanoate
- 5-amino-4-oxopentanoic acid
- 5-Amino-4-oxovaleric acid
- 5-Aminolevulinate
- aminolevulinic acid
- dALA
- delta-ALA
- delta-aminolevulinic acid
Treatment Applications
-
acrokeratosis verruciformisView Disease →
DOID:0050606
-
Bannayan-Riley-Ruvalcaba syndromeView Disease →
DOID:0050657
-
Birt-Hogg-Dube syndromeView Disease →
DOID:0050676
-
punctate palmoplantar keratodermaView Disease →
DOID:0060361
-
punctate palmoplantar keratoderma type IIIView Disease →
DOID:0060362
-
atrichia with papular lesionsView Disease →
DOID:0060689
-
punctate palmoplantar keratoderma type IView Disease →
DOID:0080214
-
Naxos diseaseView Disease →
DOID:0080551
-
hypotrichosis 14View Disease →
DOID:0080582
-
keratosis pilaris atrophicans facieiView Disease →
DOID:0080752
-
keratosis follicularis spinulosa decalvansView Disease →
DOID:0080753
-
atrophoderma vermiculataView Disease →
DOID:0080756
-
keratosis palmoplantaris striata 2View Disease →
DOID:0081109
-
white sponge nevus 1View Disease →
DOID:0081287
-
Naegeli-Franceschetti-Jadassohn syndromeView Disease →
DOID:0111528
-
oculoectodermal syndromeView Disease →
DOID:0111705
-
hypotrichosisView Disease →
DOID:4535
-
obsolete desmoplastic melanomaView Disease →
DOID:10049
-
obsolete senile nevusView Disease →
DOID:12863
-
facial hemiatrophyView Disease →
DOID:1757
-
skin glomangiomaView Disease →
DOID:2435
-
obsolete skin compound nevusView Disease →
DOID:2437
-
obsolete Hair nevusView Disease →
DOID:3164
-
Papillon-Lefevre diseaseView Disease →
DOID:3389
-
cutaneous Paget's diseaseView Disease →
DOID:3450
-
porokeratosisView Disease →
DOID:3805
-
hidrocystomaView Disease →
DOID:3893
-
hidradenomaView Disease →
DOID:3896
-
angioma serpiginosumView Disease →
DOID:4028
-
cystic basal cell carcinomaView Disease →
DOID:4302
-
skin hemangiomaView Disease →
DOID:471
-
angiokeratomaView Disease →
DOID:479
-
obsolete cellular blue nevusView Disease →
DOID:5227
-
obsolete common blue nevusView Disease →
DOID:5228
-
eccrine acrospiromaView Disease →
DOID:5442
-
clear cell hidradenomaView Disease →
DOID:5443
-
spiradenomaView Disease →
DOID:5444
-
eccrine papillary adenomaView Disease →
DOID:5446
-
cavernous hemangioma of faceView Disease →
DOID:5776
-
stork biteView Disease →
DOID:5806
-
angiokeratoma of mibelliView Disease →
DOID:5948
-
angiokeratoma circumscriptumView Disease →
DOID:5949
-
obsolete regressing nevusView Disease →
DOID:6667
-
inverted follicular keratosisView Disease →
DOID:6945
-
obsolete Spitz nevusView Disease →
DOID:7468
-
actinic keratosisView Disease →
DOID:8866
Drug Classification
-
delta-amino acidView Class →
CHEBI:35931
-
4-oxo monocarboxylic acidView Class →
CHEBI:35950
-
t132927
-
t133159
-
t133275
-
t133386
-
t133431
-
t133618
-
t133818
-
t133821
-
t133929
-
t133956
-
t134038
-
t134146
-
t134248
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 683
- oboInOwl#hasDbXref
- Wikipedia:Aminolevulinic_acid
- core#notation
- CHEBI:17549
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 683
- oboInOwl#hasDbXref
- Wikipedia:Aminolevulinic_acid
- oboInOwl#id
- CHEBI:17549
- core#notation
- CHEBI:17549
- oboInOwl#hasAlternativeId
- CHEBI:20547
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_76971
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_132970
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_12109
- chebi#is_tautomer_of
- http://purl.obolibrary.org/obo/CHEBI_356416
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_724125
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_113418
- owl#someValuesFrom
- t3078349
- owl#annotatedSource
- t134292