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oxaliplatin

CHEBI:CHEBI_31941

Definition

A platinum coordination entity that is a commonly used chemothrepeutic drug for treatment of colorectal cancer.

Chemical Information

Molecular Formula
C8H14N2O4Pt
Molecular Mass
397.28584
Charge
0
SMILES
[H][N]1([H])[C@@H]2CCCC[C@H]2[N]([H])([H])[Pt]11OC(=O)C(=O)O1
InChI
InChI=1S/C6H14N2.C2H2O4.Pt/c7-5-3-1-2-4-6(5)8;3-1(4)2(5)6;/h5-6H,1-4,7-8H2;(H,3,4)(H,5,6);/q;;+2/p-2/t5-,6-;;/m1../s1
InChIKey
ZROHGHOFXNOHSO-BNTLRKBRSA-L

Alternative Names

  • (SP-4-2-(1R-trans))-(1,2-cyclohexanediamine-N,N')(ethanedioato(2-)-O,O')platinum
  • (SP-4-2)[(1R,2R)-cyclohexane-1,2-diamine-kappa(2)N,N'][ethanedioato(2-)-kappa(2)O(1),O(2)]platinum
  • Eloxatin
  • oxalato(1,2-diaminocyclohexane)platinum(II)
  • oxaliplatin
  • Oxaliplatin
  • oxaliplatine
  • oxaliplatino
  • oxaliplatinum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:31941
oboInOwl#hasDbXref
Wikipedia:Oxaliplatin
DRON_00010000
32592

Additional References

Wikipedia:Oxaliplatin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

rxcui
1797528
manufacturer_name
FOSUN PHARMA USA INC.
package_marketing_start_date
31-JAN-05
unii
04ZR38536J
spl_set_id
d6178bc6-9dae-413f-8f47-de75d576c5b8
package_description
125 g in 1 BOTTLE, PLASTIC (72659-865-00)
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
dosage_form
INJECTION, SOLUTION, CONCENTRATE
labeler_name
Heraeus Precious Metals GmbH & Co. KG
marketing_start_date
20070521
application_number
ANDA207385
spl_id
806ca379-08e9-459b-ad93-5ae050d432a0
product_ndc
60505-6287
core#notation
CHEBI:31941
active_ingredient_strength
200 mg/40mL
active_ingredient_name
OXALIPLATIN
nui
N0000175073
upc
0368083170011
pharm_class_epc
Platinum-based Drug [EPC]
pharm_class
Platinum-containing Compounds [EXT]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
route
INTRAVENOUS
package_ndc
68083-176-01
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Oxaliplatin
DRON_00010000
32592
oboInOwl#id
CHEBI:31941
generic_name
OXALIPLATIN
brand_name
OXALIPLATIN
brand_name_base
OXALIPLATIN
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35610
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
has_treatment
http://purl.obolibrary.org/obo/DOID_5923
owl#annotatedSource
t182490
owl#someValuesFrom
t2915351
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113402
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect17820