Discuss This Drug

famciclovir

CHEBI:CHEBI_4974

Definition

2-Amino-9H-purine in which the hydrogen at position 9 is substituted by a 4-acetoxy-3-(acetoxymethyl)but-1-yl group. A prodrug of the antiviral penciclovir, it is used for the treatment of acute herpes zoster (shingles), for the treatment or suppression of recurrent genital herpes in immunocompetent patients and for the treatment of recurrent mucocutaneous herpes simplex infections in HIV infected patients.

Chemical Information

Molecular Formula
C14H19N5O4
Molecular Mass
321.33180
Charge
0
SMILES
CC(=O)OCC(CCn1cnc2cnc(N)nc12)COC(C)=O
InChI
InChI=1S/C14H19N5O4/c1-9(20)22-6-11(7-23-10(2)21)3-4-19-8-17-12-5-16-14(15)18-13(12)19/h5,8,11H,3-4,6-7H2,1-2H3,(H2,15,16,18)
InChIKey
GGXKWVWZWMLJEH-UHFFFAOYSA-N

Alternative Names

  • 2-(2-(2-amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate
  • 2-[(acetyloxy)methyl]-4-(2-amino-9H-purin-9-yl)butyl acetate
  • 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine
  • acetic acid 2-acetoxymethyl-4-(2-amino-purin-9-yl)-butyl ester
  • BRL-42810
  • famciclovir
  • FAMCICLOVIR
  • famciclovirum
  • Famvir
  • FCV

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Famciclovir
DRON_00010000
68099
core#notation
CHEBI:4974

Additional References

Wikipedia:Famciclovir

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
route
ORAL
marketing_start_date
20120113
spl_id
0e88852d-7326-3002-e063-6394a90a0369
package_ndc
51927-5177-0
package_description
1 kg in 1 BOTTLE (51927-5177-0)
labeler_name
AvKARE
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Famciclovir
DRON_00010000
68099
oboInOwl#hasAlternativeId
CHEBI:174284
oboInOwl#id
CHEBI:4974
generic_name
Famciclovir
brand_name
Famciclovir
brand_name_base
Famciclovir
product_type
BULK INGREDIENT
dosage_form
POWDER
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
product_ndc
51927-5177
application_number
ANDA091114
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50266
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
rxcui
199193
manufacturer_name
Apotex Corp.
package_marketing_start_date
18-APR-22
unii
QIC03ANI02
spl_set_id
b75abffb-0a90-4abd-8ed8-81be1d8fe364
core#notation
CHEBI:4974
active_ingredient_name
FAMCICLOVIR
nui
N0000175459
pharm_class_epc
Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor [EPC]
pharm_class
Nucleoside Analog [EXT]
pharm_class_moa
DNA Polymerase Inhibitors [MoA]
active_ingredient_strength
50 kg/50kg
upc
0371205609214
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_8704
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113596
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect26649
owl#annotatedSource
t235316
owl#someValuesFrom
t712551