Discuss This Drug

Trifluridine

CHEBI:CHEBI_75179

Definition

A pyrimidine 2'-deoxyribonucleoside compound having 5-trifluoromethyluracil as the nucleobase. An antiviral drug used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis.

Chemical Information

Molecular Formula
C10H11F3N2O5
Molecular Mass
296.19990
Charge
0
SMILES
OC[C@H]1O[C@H](C[C@@H]1O)n1cc(c(=O)[nH]c1=O)C(F)(F)F
InChI
InChI=1S/C10H11F3N2O5/c11-10(12,13)4-2-15(9(19)14-8(4)18)7-1-5(17)6(3-16)20-7/h2,5-7,16-17H,1,3H2,(H,14,18,19)/t5-,6+,7+/m0/s1
InChIKey
VSQQQLOSPVPRAZ-RRKCRQDMSA-N

Alternative Names

  • 2'-deoxy-5-(trifluoromethyl)uridine
  • 5-(Trifluoromethyl)deoxyuridine
  • 5-Trifluoromethyl-2-deoxyuridine
  • Trifluoromethyldeoxyuridine
  • Trifluorothymidine
  • trifluorothymine deoxyriboside
  • trifluridina
  • trifluridine
  • trifluridinum
  • Viroptic

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
10803
oboInOwl#hasDbXref
Wikipedia:Trifluridine
core#notation
CHEBI:75179

Additional References

Wikipedia:Trifluridine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
10803
oboInOwl#hasDbXref
Wikipedia:Trifluridine
oboInOwl#id
CHEBI:75179
oboInOwl#hasAlternativeId
CHEBI:9713
generic_name
trifluridine and tipiracil
brand_name
LONSURF
brand_name_base
LONSURF
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
route
OPHTHALMIC
dosage_form
SOLUTION
marketing_start_date
20010514
labeler_name
Taiho Pharmaceutical Co., Ltd.
product_ndc
64842-1020
spl_id
1376bc92-67d0-403d-b9d3-602d58df9d8c
package_ndc
64842-1020-3
application_number
NDA207981
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_63720
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
core#notation
CHEBI:75179
rxcui
1670324
nui
N0000175595
pharm_class
Thymidine Phosphorylase Inhibitors [MoA]
active_ingredient_strength
8.19 mg/1
pharm_class_moa
Nucleic Acid Synthesis Inhibitors [MoA]
pharm_class_epc
Nucleoside Analog Antiviral [EPC]
manufacturer_name
Taiho Pharmaceutical Co., Ltd.
package_marketing_start_date
20010514
active_ingredient_name
TIPIRACIL HYDROCHLORIDE
package_description
60 TABLET, FILM COATED in 1 BOTTLE (64842-1020-3)
unii
4H59KLQ0A4
spl_set_id
f5beed22-d71d-4c0d-8dca-2c7317d65d85
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_0080158
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113847
owl#annotatedSource
t287088
owl#someValuesFrom
t2995734