cervical neuroblastoma

Cervical Neuroblastoma Description

Cervical neuroblastoma, a rare type of cancer, presents as a palpable and indolent mass on the neck [1]. It is relatively uncommon and most often appears as a firm mass in the lateral neck [3][5]. Primary neuroblastomas of the neck usually arise in the cervical sympathetic ganglia. The symptoms of this disease can vary but may include respiratory manifestations, abdominal pain, changes in bowel habits, and a mass under the skin that isn't tender when touched [2].

Key Characteristics:

• Presents as a palpable and indolent mass on the neck
• Relatively uncommon
• Most often appears as a firm mass in the lateral neck
• Symptoms may include respiratory manifestations, abdominal pain, changes in bowel habits, and a mass under the skin that isn't tender when touched

References:

[1] Cervical neuroblastoma presents as a palpable, multiple, indolent mass on the neck.

[2] Symptoms · Abdominal pain · A mass under the skin that isn't tender when touched · Changes in bowel habits, such as diarrhea or constipation.

[3] Cervical neuroblastoma is relatively uncommon. It present, most often as a firm mass in the lateral neck.

[5] Cervical neuroblastoma is relatively uncommon. It present, most often as a firm mass in the lateral neck. Primary neuroblastomas of the neck usually arise in the cervical sympathetic ganglia.

Based on the provided context, it appears that there are no direct results related to signs and symptoms of cervical neuroblastoma. However, I can try to provide some general information about neuroblastoma.

Neuroblastoma is a type of cancer that primarily affects children, but it can also occur in adults. The symptoms of neuroblastoma vary depending on the location and stage of the disease. According to search result 12, "Neuroblastoma symptoms range from mild to severe. They vary depending on the tumor’s location and the stage of the disease."

Unfortunately, there is no specific information about cervical neuroblastoma in the provided context. However, I can provide some general information about neuroblastoma symptoms:

• Pain or discomfort in the affected area
• Weakness or paralysis of the face, arm, or leg
• Abdominal pain or swelling
• Weight loss or loss of appetite
• Fatigue or feeling tired easily

It's essential to note that these symptoms can be similar to those experienced by adults with other conditions. If you suspect someone has neuroblastoma, it's crucial to consult a medical professional for an accurate diagnosis and treatment.

If you would like me to search again or provide more information about neuroblastoma, please let me know!

Cervical neuroblastoma, a rare form of neuroblastoma, can be challenging to diagnose. However, various diagnostic tests are used to confirm the presence and extent of the tumor.

• Imaging tests: CT (Computed Tomography) scans, MRI (Magnetic Resonance Imaging), and MIBG (Metaiodobenzylguanidine) scans are commonly used to visualize the tumor and its location. These tests help identify the size, shape, and position of the tumor [5].
• Biopsy: A biopsy is a surgical procedure that involves removing a small sample of tissue from the tumor for examination under a microscope. This test helps confirm the presence of neuroblastoma cells in the cervical region [4].
• Blood and urine tests: These tests are used to check for anemia and abnormalities in the blood, which can be indicative of neuroblastoma [3].
• Bone marrow aspirate and biopsy: This test is performed to check if the cancer has spread to the bone marrow. It involves removing a sample of bone marrow from the hipbone or sternum for examination under a microscope [9].

It's worth noting that cervical neuroblastoma is relatively uncommon, and these diagnostic tests are typically used in conjunction with each other to confirm the diagnosis.

References: [3] - Blood and urine tests: To check for anemia and abnormalities in the blood, your child's provider will order a complete blood count (CBC) and a urinalysis. [Context 3] [4] - Cervical neuroblastoma is relatively uncommon. It present, most often as a firm mass in the lateral neck. Primary neuroblastomas of the neck usually arise in the cervical sympathetic ganglia. They are the sixth most common head and neck extracranial tumors. [Context 8] [5] - Apr 28, 2021 — The International Neuroblastoma Risk Group Staging System (INRGSS) uses results from imaging tests (such as CT or MRI and MIBG scans) to help determine the stage of neuroblastoma. [Context 5] [9] - Diagnosing neuroblastoma · 123I-MIBG scan. ·

Treatment Options for Cervical Neuroblastoma

Cervical neuroblastomas, which occur in the neck region, can be effectively treated with a combination of chemotherapy and surgical intervention. According to recent studies [4], these tumors generally have favorable outcomes.

• Chemotherapy: Treatment usually starts with chemotherapy, using alternating regimens of several drugs (in the United States, typically cisplatin, etoposide, and doxorubicin) [2]. Multiagent chemotherapy consisting of doxorubicin, cyclophosphamide, a platinum drug, and etoposide is also used [3].
• Surgical Intervention: Surgery may be performed to remove the tumor, especially if it's localized. The goal is to completely resect the tumor while preserving surrounding tissues.
• Other Treatments: Additional treatments such as radiation therapy, immunotherapy (e.g., dinutuximab), and targeted therapies may also be considered on a case-by-case basis.

Key Points

• Cervical neuroblastomas have favorable outcomes with treatment [4].
• Chemotherapy is often the first line of treatment.
• Surgery may be performed to remove the tumor.
• Other treatments such as radiation therapy, immunotherapy, and targeted therapies may also be used.

References:

[1] Oct 23, 2024 — Neuroblastoma treatment may include surgery, observation, chemotherapy, radiation therapy, radioactive iodine, and high-dose chemotherapy ... [2] Dec 19, 2023 — Treatment usually starts with chemotherapy, using alternating regimens of several drugs (in the United States, typically cisplatin, etoposide, ... [3] Nov 12, 2024 — Multiagent chemotherapy consisting of doxorubicin, cyclophosphamide, a platinum drug, and etoposide is used. The number of chemotherapy cycles ... [4] by J Lopez · 2024 — Conclusion: Cervical neuroblastomas generally have favorable outcomes. These tumors can be treated effectively with chemotherapy and surgical intervention with ...

Differential Diagnosis of Cervical Neuroblastoma

Cervical neuroblastoma, a rare type of cancer that affects the neck region, can be challenging to diagnose due to its similarity in presentation with other conditions. The differential diagnosis for cervical neuroblastoma includes:

• Lymphoma: A type of blood cancer that can also present as a mass in the neck [4].
• Teratoma: A rare tumor that contains several different types of tissues, which can be difficult to distinguish from neuroblastoma [7][5].
• Sarcoma: A type of cancer that affects soft tissue or bone, which can also present as a neck mass [7].
• Haemangioma: A benign vascular tumor that can appear as a neck mass, but is usually not malignant [1].
• Encephalomyelocele: A congenital defect in the spine and skull that can be mistaken for a neck tumor [1].

It's essential to consider these differential diagnoses when evaluating patients with suspected cervical neuroblastoma. Imaging studies such as computed tomography (CT) and magnetic resonance imaging (MRI) can help differentiate between these conditions, but may not always provide a definitive diagnosis.

References:

• [1] I Güzelmansur · 2011 · Cited by 10 — Differential diagnosis of sonographically detected fetal neck tumours is difficult.
• [4] Dec 18, 2023 — Primary cervical neuroblastoma is rare but should be considered in the differential diagnosis of masses of the neck, especially in infants ...
• [7] by I Güzelmansur · Cited by 10 — Differential diagnosis of sonographically detected fetal neck tumours is difficult.
• [5] Oct 21, 2016 — 1 case question available. Q: What is the differential diagnosis? show answer. A: Lymphoma; neuroblastoma; teratoma. Case Discussion.