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disease
Description
What is Disease?
Disease refers to an abnormal condition that affects the structure or function of part or all of the body, typically associated with specific signs and symptoms [1]. It can be defined as a particular abnormal condition that adversely affects the structure or function of all or part of an organism and is not immediately due to external factors [4].
Characteristics of Disease
Disease can manifest in various ways, including physical and mental symptoms that cause a functioning outside the normal range of accepted values [7]. It can also be described as a lack of health with both physical and mental symptoms [7]. In some cases, disease can refer to a condition affecting society or the mind, such as a depraved or morbid condition [8].
Definition of Disease
The definition of disease has evolved over time. According to the World Health Organization (WHO), "health is a state of complete physical, mental and social wellbeing and not merely the absence of disease or infirmity" [6]. This definition highlights that health is a positive concept, encompassing not only the absence of disease but also the presence of well-being.
Types of Disease
Disease can be classified into various categories, including infectious diseases caused by organisms such as bacteria, viruses, fungi, or parasites [5]. These diseases can affect humans, animals, and plants. In addition to infectious diseases, there are other types of diseases that can be caused by internal factors, such as genetic disorders or environmental factors.
In Summary
Disease is a complex concept that encompasses various aspects of health and well-being. It refers to an abnormal condition affecting the structure or function of part or all of the body, typically associated with specific signs and symptoms. The definition of disease has evolved over time, and it can be classified into different categories based on its causes and effects.
References: [1] - Context result 1 [4] - Context result 4 [6] - Context result 6 [7] - Context result 7
Additional Characteristics
- an abnormal condition that affects the structure or function of part or all of the body
- a particular abnormal condition that adversely affects the structure or function of all or part of an organism
- physical and mental symptoms that cause a functioning outside the normal range of accepted values
- a lack of health with both physical and mental symptoms
- a depraved or morbid condition
- the absence of disease or infirmity
- infectious diseases caused by organisms such as bacteria, viruses, fungi, or parasites
- genetic disorders or environmental factors
Signs and Symptoms
Understanding Signs and Symptoms
Signs and symptoms are two important concepts in medicine that help doctors diagnose and treat various diseases.
- Signs: These are physical manifestations of a disease that can be observed by others, such as a doctor or family member. Examples include:
- Skin rashes
- Coughing
- Fever
- Abdominal swelling (ascites)
- Deformed nails (nail clubbing)
- Symptoms: These are subjective experiences of a disease that can only be felt by the individual themselves, such as pain, fatigue, or dizziness. Examples include:
- Feeling tired or exhausted
- Headaches
- Sore throats
- Foot pain
According to [1], signs and symptoms vary depending on the organism causing the infection, but often include fever and fatigue.
It's worth noting that each disease entity has a unique constellation of signs and symptoms, making it easier for doctors to diagnose specific conditions. For instance, [7] states that individual signs such as fever may be found in various diseases, but when combined with other symptoms, they can help identify the underlying condition.
In some cases, symptoms can be indicative of mental health issues or emotional problems, such as anxiety, depression, or extreme mood swings [9].
References:
[1] Signs and symptoms vary depending on the organism causing the infection, but often include fever and fatigue. Mild infections may respond to rest and home ...
[7] Each disease entity has a constellation of signs and symptoms more or less uniquely its own; individual signs such as fever, however, may be found in a great ...
[9] 12 Signs and symptoms of mental illness or emotional problems · Anxiety and constant worry · Feeling depressed, empty, sad all the time, or worthless · Extreme ...
Additional Symptoms
- Skin rashes
- Coughing
- Headaches
- Abdominal swelling (ascites)
- Deformed nails (nail clubbing)
- Feeling tired or exhausted
- Sore throats
- Foot pain
- fever
Diagnostic Tests
Diagnostic Tests for Diseases
Diagnostic tests are medical procedures used to help determine if a person has a specific disease or condition. These tests can also be used to monitor the progression of a disease, check the effectiveness of treatment, and detect any potential complications.
Some common diagnostic tests include:
- Blood Tests: Blood tests can be used to diagnose a wide range of diseases, including diabetes, anemia, and infections. They involve taking a sample of blood from a vein in the arm or finger.
- Imaging Procedures: Imaging procedures such as X-rays, CT scans, and MRI scans can help pinpoint diagnoses and rule out other conditions that may be causing symptoms.
- Biopsy: A biopsy involves removing a small sample of tissue from the body to examine it under a microscope. This can be used to diagnose diseases such as cancer.
- Pap Test: The Pap test is a screening test for cervical cancer, which involves collecting cells from the cervix using a special brush or spatula.
Types of Diagnostic Tests
Diagnostic tests can be categorized into several types, including:
- Screening Tests: Screening tests are used to detect diseases in people who do not have any symptoms. Examples include mammography and colonoscopy.
- Diagnostic Tests: Diagnostic tests are used to confirm a diagnosis after symptoms have appeared. Examples include blood tests and imaging procedures.
Importance of Diagnostic Tests
Diagnostic tests play a crucial role in the diagnosis and treatment of diseases. They can help:
- Confirm a Diagnosis: Diagnostic tests can confirm whether or not a person has a specific disease.
- Monitor Treatment: Diagnostic tests can be used to monitor the effectiveness of treatment and detect any potential complications.
- Detect Complications: Diagnostic tests can also be used to detect any potential complications that may arise from a disease.
Sources:
- [1] Medical tests can help detect a condition, determine a diagnosis, plan treatment, check to see if treatment is working, or monitor the condition over time. A diagnostic test is a medical procedure used to help figure out what disease or condition a person has based on their signs and symptoms.
- [3] Information about tests such as A1C, colonoscopy, GFR, and biopsy to diagnose diabetes, digestive, kidney, and other diseases and conditions.
- [7] A test used to help figure out what disease or condition a person has based on their signs and symptoms. Diagnostic tests may also be used to help plan treatment.
- [8] Diagnostics contribute to the identification, detection and characterization of infectious and noncommunicable diseases. They also contribute to the monitoring of patients with chronic conditions.
Additional Diagnostic Tests
- Blood Tests
- Biopsy
- Diagnostic Tests
- Imaging Procedures
- Pap Test
- Screening Tests
Treatment
Medications for Disease Treatment
Medications play a crucial role in treating various diseases, from curing and preventing conditions to easing symptoms and aiding in diagnosis. Here are some key points about drug treatment:
- Types of Medications: Medicines can be categorized into several types, including:
- Curative medications: These drugs aim to cure or eliminate the disease altogether [9].
- Symptomatic medications: These medicines focus on alleviating symptoms and improving quality of life [9].
- Preventive medications: Some medications are designed to prevent diseases from occurring in the first place [9].
- Common Medications: Certain substances, such as:
- Alcohol
- Opioids
- Marijuana are commonly used for various purposes, including treating medical conditions and managing symptoms [3].
- Substance Use Disorder (SUD): SUD is a treatable mental health condition that can range from mild to severe addiction. Medications can be an effective part of treatment plans for SUD [3].
- Importance of Timely Treatment: It's essential to start treatments within 5-7 days after developing symptoms to ensure effectiveness, as highlighted in recent medical guidelines [7].
These points demonstrate the significance of medications in disease treatment and management. If you have any specific questions or would like more information on a particular topic, feel free to ask!
References: [1] Context result 1 [3] Context result 3 [9] Context result 9 [7] Context result 7
Recommended Medications
- Opioids
- Marijuana
- Curative medications
- Symptomatic medications
- Preventive medications
- Substance Use Disorder (SUD)
- alcohol
💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.
Differential Diagnosis
What is Differential Diagnosis?
A differential diagnosis (DDx) is a method of analysis used in healthcare to identify and distinguish between various diseases or conditions that can cause similar symptoms [1]. It's a crucial step in the diagnostic process, helping healthcare providers to narrow down the list of possible causes for a patient's symptoms.
Key Aspects of Differential Diagnosis
- A differential diagnosis is a list of possible conditions that share the same symptoms [2].
- It involves evaluating patient history, physical examination, and laboratory results to identify potential causes [3].
- The goal of differential diagnosis is to generate a list of plausible explanations for a patient's symptoms, which can then be further investigated or ruled out [4].
Importance of Differential Diagnosis
Differential diagnosis plays a vital role in healthcare by:
- Helping healthcare providers to avoid misdiagnosis and ensure accurate diagnoses [5].
- Allowing for the early identification of serious conditions that require prompt treatment [6].
- Facilitating effective communication between healthcare providers and patients about potential causes and next steps [7].
Tools and Resources for Differential Diagnosis
Several tools and resources are available to support differential diagnosis, including:
- Clinical decision support systems (CDSSs) that provide quick, evidence-based answers to clinical questions at the point of care [8].
- Electronic health records (EHRs) that enable healthcare providers to access patient information and generate lists of possible causes.
- Medical literature and guidelines that offer guidance on differential diagnosis for specific conditions.
References
[1] A differential diagnosis is a list of possible conditions that share the same symptoms that you described to your healthcare provider. This list is not your final answer, but rather a starting point for further investigation [1].
[2] Feb 27, 2023 — A differential diagnosis process is used to help make a final diagnosis when you have symptoms that don't have one clear cause [2].
[3] In healthcare, a differential diagnosis (DDx) is a method of analysis that distinguishes a particular disease or condition from others that present with similar symptoms [3].
[4] Jul 15, 2020 — A differential diagnosis is a list of possible conditions that share the same symptoms [4].
[5] May 28, 2024 — The differential diagnosis is a list of the most likely infectious causes or etiologies of an outbreak [5].
[6] by CE Cook · 2020 · Cited by 53 — The diagnostic process involves identifying or determining the etiology of a disease or condition through evaluation of patient history, physical examination, and laboratory results [6].
[7] May 12, 2018 — A differential diagnosis is a list of possible conditions or diseases that could be causing your symptoms [7].
[8] Differential diagnosis is the process of identifying and distinguishing between various diseases and conditions that can cause similar symptoms [8].
Additional Differential Diagnoses
- A list of possible conditions that share the same symptoms
- A method of analysis used in healthcare to identify and distinguish between various diseases or conditions that can cause similar symptoms
- Evaluating patient history, physical examination, and laboratory results to identify potential causes
- Generating a list of plausible explanations for a patient's symptoms
- Distinguishing a particular disease or condition from others that present with similar symptoms
- A list of possible infectious causes or etiologies of an outbreak
- The diagnostic process involves identifying or determining the etiology of a disease or condition through evaluation of patient history, physical examination, and laboratory results
- A list of possible conditions or diseases that could be causing your symptoms
- proximal symphalangism
- focal dystonia
- multifocal dystonia
- oromandibular dystonia
- hemidystonia
- mixed extragonadal germ cell cancer
- autoimmune disease of urogenital tract
- obsolete neurological disorder
- non-Hodgkin lymphoma
- thoracic disease
- acquired metabolic disease
- microscopic colitis
- gastroduodenal Crohn's disease
- CREST syndrome
- carnitine palmitoyltransferase II deficiency
- Dowling-Degos disease
- pontocerebellar hypoplasia type 2D
- mitochondrial complex V (ATP synthase) deficiency nuclear type 4
- punctate palmoplantar keratoderma
- Parkinson's disease 1
- Parkinson's disease 2
- Parkinson's disease 6
- Parkinson's disease 7
- Parkinson's disease 8
- carp allergy
- hypomyelinating leukodystrophy 2
- hypomyelinating leukodystrophy 12
- Griscelli syndrome type 1
- Griscelli syndrome type 2
- patterned macular dystrophy
- patterned macular dystrophy 2
- patterned macular dystrophy 3
- leukoencephalopathy with vanishing white matter
- juvenile-onset Parkinson's disease
- Parkinson's disease 20
- Niemann-Pick disease type A
- Niemann-Pick disease type B
- autosomal recessive chronic granulomatous disease 2
- autosomal recessive chronic granulomatous disease 1
- autosomal recessive chronic granulomatous disease 4
- autosomal recessive chronic granulomatous disease 3
- X-linked chronic granulomatous disease
- infantile-onset distal myopathy
- hereditary lymphedema I
- benign recurrent intrahepatic cholestasis 2
- multiple epiphyseal dysplasia 5
- multiple epiphyseal dysplasia 1
- thiamine deficiency disease
- nevoid basal cell carcinoma syndrome 1
- leukoencephalopathy with vanishing white matter 5
- autosomal recessive chronic granulomatous disease 5
- leukoencephalopathy with vanishing white matter 4
- leukoencephalopathy with vanishing white matter 3
- leukoencephalopathy with vanishing white matter 2
- leukoencephalopathy with vanishing white matter 1
- combined oxidative phosphorylation deficiency 54
- retinal macular dystrophy
- North Carolina macular dystrophy
- retinal macular dystrophy 4
- Parkinson's disease 25
- dysbaric osteonecrosis
- metaphyseal dysplasia
- Worth syndrome
- obsolete nonsyndromic congenital nail disorder 10
- Sengers syndrome
- Cytomegalovirus retinitis
- superior semicircular canal dehiscence
- punctate palmoplantar keratoderma type I
- nephrotic syndrome type 14
- nephrotic syndrome type 16
- obsolete X-linked recessive disease
- nephrotic syndrome type 4
- nephrotic syndrome type 12
- Parkinson's disease 22
- hypermanganesemia with dystonia
- hypermanganesemia with dystonia 1
- hypermanganesemia with dystonia 2
- congenital disorder of glycosylation Ih
- Fanconi renotubular syndrome 2
- Fanconi renotubular syndrome 5
- proximal symphalangism 2
- myeloid leukemia associated with Down Syndrome
- Parkinsonism
- Cockayne syndrome A
- congenital myopathy 1B
- Cowden syndrome 4
- Cowden syndrome 6
- Cowden syndrome 7
- central conducting lymphatic anomaly
- generalized lymphatic anomaly
- white sponge nevus 2
- grade II lymphomatoid granulomatosis
- glycogen storage disease Ic
- congenital myopathy
- congenital myopathy 5
- congenital myopathy 8
- congenital myopathy 15
- congenital myopathy 18
- congenital myopathy 20
- congenital myopathy 21
- epidermolytic hyperkeratosis 2
- LADD syndrome
- myoclonic dystonia 11
- familial cold autoinflammatory syndrome
- familial cold autoinflammatory syndrome 2
- age related macular degeneration 4
- X-linked Alport syndrome
- age related macular degeneration
- facioscapulohumeral muscular dystrophy
- Parkinson's disease
- hypothyroidism
- retinal vascular disease
- gastrointestinal system cancer
- chronic granulomatous disease
- liver disease
- Cowden syndrome
- muscular dystrophy
- hypoglycemia
- Charcot-Marie-Tooth disease type 2A1
- Charcot-Marie-Tooth disease type 2E
- Charcot-Marie-Tooth disease axonal type 2Q
- Charcot-Marie-Tooth disease type 4A
- Charcot-Marie-Tooth disease type 4D
- Charcot-Marie-Tooth disease type 4E
- Charcot-Marie-Tooth disease recessive intermediate C
- autosomal dominant nonsyndromic deafness 54
- primary ciliary dyskinesia 8
- neuronal ceroid lipofuscinosis 6A
- neuronal ceroid lipofuscinosis 6B
- adult hypophosphatasia
- Gaucher's disease type I
- Gaucher's disease type III
- CADASIL 2
- platelet-type bleeding disorder 18
- congenital bile acid synthesis defect 4
- congenital muscular dystrophy-dystroglycanopathy A14
- congenital muscular dystrophy-dystroglycanopathy type A5
- gamma-glutamyl transpeptidase deficiency
- psoriasis 15
- psoriasis 6
- lymphedema-distichiasis syndrome
- autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions 5
- Charcot-Marie-Tooth disease type 2A2B
- Temtamy syndrome
- diffuse cystic renal dysplasia
- Leber plus disease
- nuclear type mitochondrial complex I deficiency 4
- Schindler disease
- muscular dystrophy-dystroglycanopathy type B4
- Fanconi syndrome
- alpha thalassemia
- CADASIL
- hypogonadism
- autoimmune hepatitis
- splenic disease
- nephrolithiasis
- multiple endocrine neoplasia type 2B
- neuroretinitis
- thalassemia
- hypopyon ulcer
- hypopyon
- patellar tendinitis
- gastric fundus cancer
- obsolete steatorrhea
- obsolete bacterial gastroenteritis
- pseudotumor cerebri
- retinal vasculitis
- palindromic rheumatism
- denture stomatitis
- Creutzfeldt-Jakob disease
- obsolete nerve deafness
- peripheral retinal degeneration
- obsolete hearing disease
- conjugate gaze palsy
- ulceration of vulva
- paracoccidioidomycosis
- pseudobulbar palsy
- choreatic disease
- obsolete cryptococcal gastroenteritis
- balanoposthitis
- Sneddon syndrome
- Rift Valley fever
- biliary atresia
- post-vaccinal encephalitis
- clonorchiasis
- chancroid
- Fox-Fordyce disease
- Norum disease
- obsolete acute glomerulonephritis with lesion of rapidly progressive glomerulonephritis
- norwegian scabies
- Machado-Joseph disease
- beta-ketothiolase deficiency
- colon lymphoma
- degeneration of macula and posterior pole
- skin cancer
- thyroiditis
- peptic ulcer disease
- duodenal ulcer
- reflex sympathetic dystrophy
- obsolete constipation
- Flinders Island spotted fever
- podoconiosis
- inhalation anthrax
- obsolete tuberculous mesenteric gland
- tick-borne encephalitis
- parasitic Ichthyosporea infectious disease
- obsolete Simplexvirus infectious disease
- primary bacterial infectious disease
- obsolete commensal Actinomycetales infectious disease
- Danon disease
- white sponge nevus
- Walker-Warburg syndrome
- hereditary lymphedema
- gummatous syphilis
- vitelliform macular dystrophy
- dyskinetic cerebral palsy
- congenital bile acid synthesis defect
- Birk-Barel syndrome
- neuroacanthocytosis
- N syndrome
- factor XIII deficiency
- obsolete primary Spirochaetales infectious disease
- leptospirosis
- obsolete primary Actinomycetales infectious disease
- Wernicke encephalopathy
- basal cell carcinoma
- malignant histiocytic disease
- hepatic flexure cancer
- obsolete Witkop-Von Sallmann disease
- glycogen storage disease III
- glycogen storage disease Ia
- glycogen storage disease IV
- Mycobacterium avium complex disease
- familial Mediterranean fever
- Pelizaeus-Merzbacher disease
- demyelinating disease
- obsolete infectious canine hepatitis
- alpha-mannosidosis
- anal Paget's disease
- cutaneous Paget's disease
- Leigh disease
- olfactory nerve disease
- obsolete Torovirus infectious disease
- micronodular basal cell carcinoma
- space motion sickness
- acquired hemangioma
- arteriosclerosis obliterans
- hemoglobin E disease
- stomach carcinoma
- Achenbach syndrome
- pellagra
- lichen nitidus
- chickenpox
- vascular dementia
- fasciitis
- plantar fasciitis
- polycystic liver disease 3 with or without kidney cysts
- retinal macular dystrophy 2
- spastic tetraplegia, thin corpus callosum, and progressive microcephaly
Additional Information
- oboInOwl#hasOBONamespace
- disease_ontology
- oboInOwl#hasDbXref
- UMLS_CUI:C0012634
- oboInOwl#id
- DOID:4
- core#notation
- DOID:4
- IAO_0000115
- A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.
- rdf-schema#label
- disease
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/doid#NCIthesaurus
- rdf-schema#subClassOf
- http://purl.obolibrary.org/obo/DOID_9297
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- 22-rdf-syntax-ns#first
- t332048
- IAO_0000700
- http://purl.obolibrary.org/obo/doid.owl
- owl#annotatedSource
- t427661
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_symptom_2831
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It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.