vincaleukoblastine
CHEBI:CHEBI_27375
Chemical Information
- Molecular Formula
- C46H58N4O9
- Molecular Mass
- 810.97410
- Charge
- 0
- SMILES
- [H][C@@]12N3CC[C@@]11c4cc(c(OC)cc4N(C)[C@@]1([H])[C@](O)([C@H](OC(C)=O)[C@]2(CC)C=CC3)C(=O)OC)[C@]1(C[C@@H]2CN(CCc3c1[nH]c1ccccc31)C[C@](O)(CC)C2)C(=O)OC
- InChI
- InChI=1S/C46H58N4O9/c1-8-42(54)23-28-24-45(40(52)57-6,36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2,37(44)50)39(59-27(3)51)46(38,55)41(53)58-7/h10-14,16,21-22,28,37-39,47,54-55H,8-9,15,17-20,23-26H2,1-7H3/t28-,37+,38-,39-,42+,43-,44-,45+,46+/m1/s1
- InChIKey
- JXLYSJRDGCGARV-XQKSVPLYSA-N
Alternative Names
- (+)-vinblastine
- (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE
- vinblastina
- vinblastine
- vinblastinum
- vincaleukoblastine
- VLB
Treatment Applications
-
obsolete balloon cell nevusView Disease →
DOID:7469
-
central epithelioid sarcomaView Disease →
DOID:7492
-
sarcomatosis of the meningesView Disease →
DOID:7613
-
meninges sarcomaView Disease →
DOID:7614
-
neonatal leukemiaView Disease →
DOID:7756
-
adult epithelioid sarcomaView Disease →
DOID:8282
-
congenital granular cell tumorView Disease →
DOID:8303
-
Hodgkin's paragranulomaView Disease →
DOID:8642
-
myeloid sarcomaView Disease →
DOID:8683
-
subacute monocytic leukemiaView Disease →
DOID:8696
-
adult T-cell leukemia/lymphomaView Disease →
DOID:0050523
-
vulvar benign neoplasmView Disease →
DOID:0060109
-
parameningeal embryonal rhabdomyosarcomaView Disease →
DOID:0060338
-
Phelan-McDermid syndromeView Disease →
DOID:0080354
-
severe congenital neutropenia 1View Disease →
DOID:0080625
-
nasal type extranodal NK/T-cell lymphomaView Disease →
DOID:0080797
-
Tukel syndromeView Disease →
DOID:0081021
-
DICER1 syndromeView Disease →
DOID:0081063
-
hematologic cancerView Disease →
DOID:2531
-
chronic myeloid leukemiaView Disease →
DOID:8552
-
acute monocytic leukemiaView Disease →
DOID:8864
-
cone-rod dystrophy 19View Disease →
DOID:0111025
-
lymphoid leukemiaView Disease →
DOID:1037
-
obsolete lymphoid leukemiaView Disease →
DOID:10747
-
labium majus cancerView Disease →
DOID:11905
-
labia minora cancerView Disease →
DOID:1243
-
obsolete classic Kaposi's sarcomaView Disease →
DOID:12763
-
central nervous system leukemiaView Disease →
DOID:12969
-
hemangioblastomaView Disease →
DOID:5241
-
pancreas lymphomaView Disease →
DOID:1792
-
vulvar squamous papillomaView Disease →
DOID:2071
-
vulvar sarcomaView Disease →
DOID:2096
-
obsolete megakaryocytic tumorView Disease →
DOID:2225
-
choroid plexus papillomaView Disease →
DOID:2626
-
hemangiopericytomaView Disease →
DOID:264
-
obsolete leukemoid reactionView Disease →
DOID:3166
-
pleomorphic rhabdomyosarcomaView Disease →
DOID:3250
-
subacute leukemiaView Disease →
DOID:3264
-
choroid plexus cancerView Disease →
DOID:3540
-
adult choroid plexus cancerView Disease →
DOID:3542
-
hemangiopericytic tumorView Disease →
DOID:3850
-
ectomesenchymomaView Disease →
DOID:4055
-
obsolete relapsed angiosarcomaView Disease →
DOID:4502
-
conventional angiosarcomaView Disease →
DOID:4512
-
classic pulmonary blastomaView Disease →
DOID:4767
-
basophilic adenocarcinomaView Disease →
DOID:4915
-
meninges hemangiopericytomaView Disease →
DOID:4957
-
hobnail hemangiomaView Disease →
DOID:505
-
retinal hemangioblastomaView Disease →
DOID:5240
-
spindle cell synovial sarcomaView Disease →
DOID:5487
-
macrotrabecular hepatoblastomaView Disease →
DOID:5798
-
cerebellar angioblastomaView Disease →
DOID:6500
-
obsolete skin lymphomaView Disease →
DOID:6761
-
peripheral epithelioid sarcomaView Disease →
DOID:6988
-
obsolete atypical vulvar nevusView Disease →
DOID:7075
-
childhood epithelioid sarcomaView Disease →
DOID:7095
Drug Classification
-
t158868
-
t158878
-
t159159
-
methyl esterView Class →
CHEBI:25248
-
tertiary alcoholView Class →
CHEBI:26878
-
organic heterotetracyclic compoundView Class →
CHEBI:38163
-
tertiary amino compoundView Class →
CHEBI:50996
-
organic heteropentacyclic compoundView Class →
CHEBI:38164
-
acetate esterView Class →
CHEBI:47622
-
vinca alkaloidView Class →
CHEBI:27288
-
indole alkaloid fundamental parentView Class →
CHEBI:38482
-
t158860
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- core#notation
- CHEBI:27375
- DRON_00010000
- 11198
- oboInOwl#hasDbXref
- Wikipedia:Vinblastine
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- core#notation
- CHEBI:27375
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 11198
- oboInOwl#hasDbXref
- Wikipedia:Vinblastine
- oboInOwl#hasAlternativeId
- CHEBI:9983
- oboInOwl#id
- CHEBI:27375
- listing_expiration_date
- 20241231
- dosage_form
- POWDER
- marketing_start_date
- 19820512
- active_ingredient_strength
- 200 g/200g
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- package_marketing_start_date
- 12-MAY-82
- labeler_name
- Minakem High Potent SA
- generic_name
- Vinblastine Sulphate
- product_ndc
- 48954-588
- spl_id
- 0bb93c0e-30be-7185-e063-6294a90a5ba1
- active_ingredient_name
- VINBLASTINE SULFATE
- package_ndc
- 48954-588-07
- package_description
- 1 BOTTLE, GLASS in 1 BAG (48954-588-07) / 374.5 g in 1 BOTTLE, GLASS
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_61951
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_8567
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_112683
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_36373
- owl#annotatedSource
- t159166
- owl#someValuesFrom
- t540652
- chebi#has_parent_hydride
- http://purl.obolibrary.org/obo/CHEBI_28445