Discuss This Drug

exemestane

CHEBI:CHEBI_4953

Definition

A 17-oxo steroid that is androsta-1,4-diene-3,17-dione in which the hydrogens at position 6 are replaced by a double bond to a methylene group. A selective inhibitor of the aromatase (oestrogen synthase) system, it is used in the treatment of advanced breast cancer.

Chemical Information

Molecular Formula
C20H24O2
Molecular Mass
296.40340
Charge
0
SMILES
[H][C@@]12CC(=C)C3=CC(=O)C=C[C@]3(C)[C@@]1([H])CC[C@]1(C)C(=O)CC[C@@]21[H]
InChI
InChI=1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1
InChIKey
BFYIZQONLCFLEV-DAELLWKTSA-N

Alternative Names

  • 6-methyleneandrosta-1,4-diene-3,17-dione
  • 6-methylideneandrosta-1,4-diene-3,17-dione
  • exemestane
  • Exemestane
  • exemestano
  • exemestanum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
258494
oboInOwl#hasDbXref
Wikipedia:Exemestane
core#notation
CHEBI:4953

Additional References

Wikipedia:Exemestane

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
258494
oboInOwl#hasDbXref
Wikipedia:Exemestane
oboInOwl#id
CHEBI:4953
core#notation
CHEBI:4953
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50790
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_parent_hydride
http://purl.obolibrary.org/obo/CHEBI_35509
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_5310
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect26485
owl#annotatedSource
t235270
owl#someValuesFrom
t824303
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113802