Discuss This Drug

Floxuridine

CHEBI:CHEBI_60761

Definition

A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.

Chemical Information

Molecular Formula
C9H11FN2O5
Molecular Mass
246.19240
Charge
0
SMILES
OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
InChI
InChI=1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
InChIKey
ODKNJVUHOIMIIZ-RRKCRQDMSA-N

Alternative Names

  • 1-(2-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil
  • 1-beta-D-2'-Deoxyribofuranosyl-5-flurouracil
  • 1beta-D-2'-Deoxyribofuranosyl-5-flurouracil
  • 2'-Deoxy-5-fluorouridine
  • 5-Fluoro-2-desoxyuridine
  • 5-fluoro-2'-deoxyuridine
  • 5-fluoro-2'-deoxyuridine
  • 5-Fluorodeoxyuridine
  • 5-Fluorouracil 2'-deoxyriboside
  • 5-Fluorouracil deoxyriboside
  • 5FDU
  • beta-5-Fluoro-2'-deoxyuridine
  • Deoxyfluorouridine
  • FdU
  • floxiridina
  • Floxuridin
  • floxuridine
  • Floxuridine
  • floxuridinum
  • Fluorodeoxyuridine
  • Fluoruridine deoxyribose
  • Fluoruridine Deoxyribose

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:60761
oboInOwl#hasDbXref
Wikipedia:Floxuridine
DRON_00010000
4488

Additional References

Wikipedia:Floxuridine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:60761
active_ingredient_strength
100 mg/mL
nui
M0006020
pharm_class_epc
Antimetabolite [EPC]
pharm_class
Deoxyuridine [CS]
pharm_class_cs
Deoxyuridine [CS]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Floxuridine
DRON_00010000
4488
oboInOwl#id
CHEBI:60761
generic_name
FLOXURIDINE
brand_name
Floxuridine
brand_name_base
Floxuridine
rxcui
310351
product_type
HUMAN PRESCRIPTION DRUG
listing_expiration_date
20241231
marketing_category
ANDA
labeler_name
JND Therapeutics, Inc.
manufacturer_name
JND Therapeutics, Inc.
dosage_form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
marketing_start_date
20010315
package_marketing_start_date
20010315
route
INTRA-ARTERIAL
product_ndc
0143-9270
application_number
ANDA075837
spl_id
0ee8505b-6680-410d-94bf-d55558a8c0e8
active_ingredient_name
FLOXURIDINE
package_ndc
0143-9270-01
package_description
1 VIAL in 1 BOX, UNIT-DOSE (0143-9270-01) / 5 mL in 1 VIAL
unii
039LU44I5M
spl_set_id
e3c2e3e7-bc83-465d-b615-3ad56580b3a7
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_132992
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
has_treatment
http://purl.obolibrary.org/obo/DOID_5245
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_112961
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect29879
owl#annotatedSource
t256079
owl#someValuesFrom
t3011168