Floxuridine
CHEBI:CHEBI_60761
Definition
A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Chemical Information
- Molecular Formula
- C9H11FN2O5
- Molecular Mass
- 246.19240
- Charge
- 0
- SMILES
- OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
- InChI
- InChI=1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
- InChIKey
- ODKNJVUHOIMIIZ-RRKCRQDMSA-N
Alternative Names
- 1-(2-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil
- 1-beta-D-2'-Deoxyribofuranosyl-5-flurouracil
- 1beta-D-2'-Deoxyribofuranosyl-5-flurouracil
- 2'-Deoxy-5-fluorouridine
- 5-Fluoro-2-desoxyuridine
- 5-fluoro-2'-deoxyuridine
- 5-fluoro-2'-deoxyuridine
- 5-Fluorodeoxyuridine
- 5-Fluorouracil 2'-deoxyriboside
- 5-Fluorouracil deoxyriboside
- 5FDU
- beta-5-Fluoro-2'-deoxyuridine
- Deoxyfluorouridine
- FdU
- floxiridina
- Floxuridin
- floxuridine
- Floxuridine
- floxuridinum
- Fluorodeoxyuridine
- Fluoruridine deoxyribose
- Fluoruridine Deoxyribose
Treatment Applications
-
liver fibrosarcomaView Disease →
DOID:8022
-
periampullary adenocarcinomaView Disease →
DOID:8110
-
postcricoid region cancerView Disease →
DOID:8660
-
liver lymphomaView Disease →
DOID:901
-
liver fibromaView Disease →
DOID:907
-
liver leiomyomaView Disease →
DOID:917
-
gastrointestinal system benign neoplasmView Disease →
DOID:0050624
-
gastrointestinal carcinomaView Disease →
DOID:0050922
-
duodenum adenomaView Disease →
DOID:0050927
-
pharynx cancerView Disease →
DOID:0060119
-
hepatoid adenocarcinomaView Disease →
DOID:0060534
-
childhood hepatocellular carcinomaView Disease →
DOID:0070322
-
adult hepatocellular carcinomaView Disease →
DOID:0070328
-
hepatobiliary system cancerView Disease →
DOID:0080355
-
gastroesophageal cancerView Disease →
DOID:0080374
-
ampulla of Vater benign neoplasmView Disease →
DOID:10022
-
jejunal cancerView Disease →
DOID:13499
-
duodenal benign neoplasmView Disease →
DOID:1737
-
hepatobiliary benign neoplasmView Disease →
DOID:3117
-
gastrointestinal system cancerView Disease →
DOID:3119
-
fibrolamellar carcinomaView Disease →
DOID:5015
-
retroperitoneal cancerView Disease →
DOID:5875
-
hepatocellular carcinomaView Disease →
DOID:684
-
oral cavity cancerView Disease →
DOID:8618
-
familial hepatic adenomaView Disease →
DOID:0111366
-
ampulla of Vater cancerView Disease →
DOID:10020
-
duodenum cancerView Disease →
DOID:10021
-
obsolete recurrent duodenal cancerView Disease →
DOID:10815
-
duodenum adenocarcinomaView Disease →
DOID:10816
-
obsolete liver metastasisView Disease →
DOID:12722
-
malignant visceral pleura tumorView Disease →
DOID:14033
-
esophageal cancerView Disease →
DOID:5041
-
hepatic flexure cancerView Disease →
DOID:260
-
liver angiosarcomaView Disease →
DOID:268
-
liver sarcomaView Disease →
DOID:270
-
hemangioma of liverView Disease →
DOID:271
-
jejunal neoplasmView Disease →
DOID:3218
-
gallbladder adenocarcinomaView Disease →
DOID:3500
-
liver cancerView Disease →
DOID:3571
-
liver rhabdomyosarcomaView Disease →
DOID:4047
-
gastrointestinal adenomaView Disease →
DOID:4147
-
malignant adenofibromaView Disease →
DOID:4422
-
gallbladder angiosarcomaView Disease →
DOID:4513
-
obsolete peritoneal neoplasmView Disease →
DOID:4884
-
sclerosing hepatic carcinomaView Disease →
DOID:5026
-
gastric leiomyosarcomaView Disease →
DOID:5280
-
liver leiomyosarcomaView Disease →
DOID:5296
-
mixed hepatoblastomaView Disease →
DOID:5789
-
gastric diffuse adenocarcinomaView Disease →
DOID:6217
-
hepatoblastomaView Disease →
DOID:687
-
gastric cardia adenocarcinomaView Disease →
DOID:6271
-
hepatic osteogenic sarcomaView Disease →
DOID:6370
-
gastric tubular adenocarcinomaView Disease →
DOID:6595
-
liver carcinomaView Disease →
DOID:686
-
adenomatoid tumorView Disease →
DOID:746
-
duodenal gastrinomaView Disease →
DOID:7959
Drug Classification
-
pyrimidine 2'-deoxyribonucleosideView Class →
CHEBI:19255
-
nucleoside analogueView Class →
CHEBI:60783
-
organofluorine compoundView Class →
CHEBI:37143
-
t254880
-
t254986
-
t255221
-
t255696
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Floxuridine
- DRON_00010000
- 4488
- core#notation
- CHEBI:60761
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Floxuridine
- DRON_00010000
- 4488
- oboInOwl#id
- CHEBI:60761
- core#notation
- CHEBI:60761
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_132992
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_5245
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_112961
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect29879
- owl#annotatedSource
- t256079
- owl#someValuesFrom
- t3011168