Floxuridine

CHEBI:CHEBI_60761

Definition

A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.

Chemical Information

Molecular Formula
C9H11FN2O5
Molecular Mass
246.19240
Charge
0
SMILES
OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
InChI
InChI=1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
InChIKey
ODKNJVUHOIMIIZ-RRKCRQDMSA-N

Alternative Names

  • 1-(2-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil
  • 1-beta-D-2'-Deoxyribofuranosyl-5-flurouracil
  • 1beta-D-2'-Deoxyribofuranosyl-5-flurouracil
  • 2'-Deoxy-5-fluorouridine
  • 5-Fluoro-2-desoxyuridine
  • 5-fluoro-2'-deoxyuridine
  • 5-fluoro-2'-deoxyuridine
  • 5-Fluorodeoxyuridine
  • 5-Fluorouracil 2'-deoxyriboside
  • 5-Fluorouracil deoxyriboside
  • 5FDU
  • beta-5-Fluoro-2'-deoxyuridine
  • Deoxyfluorouridine
  • FdU
  • floxiridina
  • Floxuridin
  • floxuridine
  • Floxuridine
  • floxuridinum
  • Fluorodeoxyuridine
  • Fluoruridine deoxyribose
  • Fluoruridine Deoxyribose

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Floxuridine
DRON_00010000
4488
core#notation
CHEBI:60761

Additional References

Wikipedia:Floxuridine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Floxuridine
DRON_00010000
4488
oboInOwl#id
CHEBI:60761
core#notation
CHEBI:60761
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_132992
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_5245
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_112961
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect29879
owl#annotatedSource
t256079
owl#someValuesFrom
t3011168